Results 131 to 140 of about 55,791 (279)

Three-Dimensional Trilineage Differentiation Conditions for Human Induced Pluripotent Stem Cells

open access: yesBioengineering
Human induced pluripotent stem cells (hiPSCs) hold great potential for regenerative medicine. However, optimizing their differentiation into specific lineages within three-dimensional (3D) scaffold-based culture systems that mimic in vivo environments ...
Md Sharifur Rahman   +7 more
doaj   +1 more source

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang   +11 more
wiley   +1 more source

Ethanol Induces Craniofacial Defects in Bmp Mutants Independent of nkx2.3 by Elevating Cranial Neural Crest Cell Apoptosis

open access: yesBiomedicines
Background: Craniofacial malformations lie at the heart of fetal alcohol spectrum disorders (FASDs). While there is growing evidence for a genetic component in FASDs, little is known of the cellular mechanisms underlying these ethanol-sensitive loci in ...
Hieu D. L. Vo, C. Ben Lovely
doaj   +1 more source

A perspective from the Mesozoic: Evolutionary changes of the mammalian skull and their influence on feeding efficiency and high‐frequency hearing

open access: yesThe Anatomical Record, Volume 309, Issue 9, Page 2315-2330, September 2026.
Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

open access: yesInterdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He   +3 more
wiley   +1 more source

Regulation of lung endoderm progenitor cell behavior by miR302/367

open access: yes, 2011
The temporal and spatial control of organ-specific endoderm progenitor development is poorly understood. miRNAs affect cell function by regulating programmatic changes in protein expression levels.
Feiyan Liu   +6 more
core   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song   +4 more
wiley   +1 more source

A Label‐Free Ultraviolet Photoacoustic Microscopy Enables Nuclear Imaging and Toxicity Assessment in an Intact Brain Organoid

open access: yesSmall, Volume 22, Issue 51, 11 September 2026.
Ultraviolet photoacoustic microscopy enables label‐free visualization of nuclear morphology in intact human brain organoids. By exploiting endogenous nucleic acid absorption at 266 nm, this approach resolves individual nuclei without staining or sectioning.
Hyunjun Kye   +5 more
wiley   +1 more source

Developmental Fates of Progenitor/Undifferentiated Cells With Histone Trimethylation Tags in the Stony Coral, Acropora tenuis

open access: yesDevelopment, Growth &Differentiation, Volume 68, Issue 7, September 2026.
In the stony coral, Acropora tenuis, embryos and larvae have progenitor/undifferentiated cells. Undifferentiated‐like cells differentiate into the pharyngeal stomodeum at an early larval stage, and nerve progenitors possess the dual potential to differentiate into nerve cells and vacuolated hyaline cells, depending on the oral‐aboral position ...
Kaz Kawamura   +2 more
wiley   +1 more source

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