Results 111 to 120 of about 64,162 (237)

The Role of Long Non-Coding RNAs in Human Endoderm Differentiation

open access: yesNon-Coding RNA
The human genome sequencing revealed a vast complexity of transcripts, with over 80% of the genome being transcribed into non-coding RNAs. In particular, long non-coding RNAs (lncRNAs) have emerged as critical regulators of various cellular processes ...
Annanda Lyra Ribeiro   +1 more
doaj   +1 more source

endoderm

open access: yes
Citation: 'endoderm' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10659 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

Developmental gene regulatory network architecture across 500 million years of echinoderm evolution [PDF]

open access: yes, 2003
Evolutionary change in morphological features must depend on architectural reorganization of developmental gene regulatory networks (GRNs), just as true conservation of morphological features must imply retention of ancestral developmental GRN features ...
Cameron, R. Andrew   +3 more
core  

High‐Grade Immature Teratoma in a 20‐Month‐Old Girl: A Rare Case With Cross‐Midline Presentation and Ovarian Torsion

open access: yesReproductive, Female and Child Health, Volume 5, Issue 2, June 2026.
ABSTRACT Background Immature ovarian teratomas are rare malignant germ cell tumours, particularly in children under 2 years old. Ovarian torsion may further obscure diagnosis by altering adnexal anatomy and radiological interpretation. Case Presentation A 20‐month‐old girl presented with persistent vomiting, abdominal distension, and poor oral intake ...
Jia Chyi Tay   +3 more
wiley   +1 more source

Three-Dimensional Trilineage Differentiation Conditions for Human Induced Pluripotent Stem Cells

open access: yesBioengineering
Human induced pluripotent stem cells (hiPSCs) hold great potential for regenerative medicine. However, optimizing their differentiation into specific lineages within three-dimensional (3D) scaffold-based culture systems that mimic in vivo environments ...
Md Sharifur Rahman   +7 more
doaj   +1 more source

Identification of Common Blood Metabolic Derangements Using Magnetic Resonance Signatures of the Pancreas and Liver

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4162-4175, May 2026.
ABSTRACT Aim To investigate whether common disturbances of glucose and lipid metabolism can be automatically identified from magnetic resonance signatures of the pancreas and liver. Methods In this proof‐of‐principle study, 100 individuals with a history of pancreatitis—a relatively homogeneous population at risk for metabolic derangements—underwent ...
Wandia Kimita   +5 more
wiley   +1 more source

Ethanol Induces Craniofacial Defects in Bmp Mutants Independent of nkx2.3 by Elevating Cranial Neural Crest Cell Apoptosis

open access: yesBiomedicines
Background: Craniofacial malformations lie at the heart of fetal alcohol spectrum disorders (FASDs). While there is growing evidence for a genetic component in FASDs, little is known of the cellular mechanisms underlying these ethanol-sensitive loci in ...
Hieu D. L. Vo, C. Ben Lovely
doaj   +1 more source

Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors. [PDF]

open access: yes, 2019
In vitro gametogenesis is the process of making germline cells from human pluripotent stem cells. The foundation of this model is the quality of the first progenitors called primordial germ cells (PGCs), which in vivo are specified during the peri ...
Aslanyan, Marianna   +11 more
core  

The epithelium of the dorsal marginal zone of Xenopus has organizer properties [PDF]

open access: yes, 1992
We have investigated the properties of the epithelial layer of the dorsal marginal zone (DMZ) of the Xenopus laevis early gastrula and found that it has inductive properties similar to those of the entire Spemann organizer.
Keller, Ray, Shih, John
core  

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