Results 111 to 120 of about 55,791 (279)

Paradoxical Role of DNA Methylation in Activation of FoxA2 Gene Expression during Endoderm Development*

open access: yesJournal of Biological Chemistry, 2014
Background: The transcription factor FoxA2 is a key mediator of endoderm development and pancreas gene expression. Results: DNA methylation is paradoxically associated with active expression of the FoxA2 gene. Conclusion: Developmental control genes such
Keren Bahar Halpern, Tal Vana, M. Walker
semanticscholar   +1 more source

Anatomy and Histology of the Midgut of Atopozelus opsimus (Heteroptera: Reduviidae)

open access: yesActa Zoologica, EarlyView.
ABSTRACT Atopozelus opsimus Elkins, 1954 (Heteroptera: Reduviidae) preys on forest and agricultural pests but also feeds on extrafloral nectar; however, its alimentary canal is poorly understood. The aim was to describe the anatomy and histology of the A. opsimus midgut. The alimentary canal of female and male A.
Bruna Silva Lisboa   +6 more
wiley   +1 more source

Endoderm patterning in Xenopus laevis

open access: yes, 2004
The endoderm is the inner germ layer of the vertebrate embryo from which the respiratory and digestive systems are derived. These include organs such as the liver, pancreas, stomach, lungs and intestine.
Costa, R
core  

Xsox17α and -β Mediate Endoderm Formation in Xenopus [PDF]

open access: yes, 1997
We have isolated two Xenopus relatives of murine Sox17 expressed in gastrula presumptive endoderm. Xsox17α and -β expression can be induced in animal caps by activin, but not by FGF. Ectopic expression of these genes in animal caps induces the expression
Clements, Debbie   +4 more
core   +1 more source

Heterodimers reign in the embryo

open access: yeseLife, 2017
Experiments by three independent groups on zebrafish have clarified the role of two signaling factors, Nodal and Gdf3, during the early stages of ...
Benjamin Tajer, Mary C Mullins
doaj   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

open access: yesCell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang   +5 more
wiley   +1 more source

Sensing oxygen inside and out

open access: yeseLife, 2017
Neuroendocrine cells act as oxygen sensors in animals from fish to humans, but the evolutionary origins of these cells are only just becoming clear.
Maria R Stupnikov, Wellington V Cardoso
doaj   +1 more source

Human iPSC‐Derived Vascularised Lung Organoids for Modelling COPD and Pulmonary Hypertension

open access: yesCell Proliferation, EarlyView.
Vascularised lung organoids (vLOs) that faithfully mimic human lung tissue architecture and disease pathology are critical for advancing pulmonary research but remain challenging to generate. Here, we developed a robust self‐organisation protocol to produce vLOs with cellular heterogeneity and functional vasculature. The engineered blood vessels within
Simin Jiang   +14 more
wiley   +1 more source

Endoderm development - from patterning to organogenesis

open access: yes
Although the ectoderm and mesoderm have been the focus of intensive work in the recent era of studies on the molecular control of vertebrate development, the endoderm has received less attention.
Melton, D. A., Grapin-Botton, A.
core   +1 more source

20th Anniversary of human‐induced pluripotent stem cells and the role of microscopy

open access: yesJournal of Microscopy, EarlyView.
Abstract It has been 20 years since the pioneering work of Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University led to the first successful generation of induced pluripotent stem cells (iPSCs) from mouse embryonic and adult fibroblast cells. iPSCs have the capacity to differentiate into any type of cell in the human body, and as such, they have ...
Philomena Hallford   +3 more
wiley   +1 more source

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