Results 91 to 100 of about 64,162 (237)

Profile of Inflammation-associated genes during Hepatic Differentiation of Human Pluripotent Stem Cells

open access: yesData in Brief, 2015
Expression of genes associated with inflammation was analyzed during differentiation of human pluripotent stem cells (PSCs) to hepatic cells. Messenger RNA transcript profiles of differentiated endoderm (day 5), hepatoblast (day 15) and hepatocyte-like ...
Joseph Ignatius Irudayam   +10 more
doaj   +1 more source

Anatomy and Histology of the Midgut of Atopozelus opsimus (Heteroptera: Reduviidae)

open access: yesActa Zoologica, EarlyView.
ABSTRACT Atopozelus opsimus Elkins, 1954 (Heteroptera: Reduviidae) preys on forest and agricultural pests but also feeds on extrafloral nectar; however, its alimentary canal is poorly understood. The aim was to describe the anatomy and histology of the A. opsimus midgut. The alimentary canal of female and male A.
Bruna Silva Lisboa   +6 more
wiley   +1 more source

Binary specification of nerve cord and notochord cell fates in ascidian embryos [PDF]

open access: yes, 2001
In the ascidian embryo, the nerve cord and notochord of the tail of tadpole larvae originate from the precursor blastomeres for both tissues in the 32-cell-stage embryo. Each fate is separated into two daughter blastomeres at the next cleavage.
Makabe, Kazuhiro W.   +3 more
core  

Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis [PDF]

open access: yes, 2017
This work was supported by British Heart Foundation (BHF Project Grant no PG/13/23/30080 to B.A.A and S.H.), Biotechnology and Biological Sciences Research Council (BB/M001695/1 to S.H.) and the University of Aberdeen (for A.T.L).
Afouda, Boni A   +3 more
core   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

open access: yesCell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang   +11 more
wiley   +1 more source

Heterodimers reign in the embryo

open access: yeseLife, 2017
Experiments by three independent groups on zebrafish have clarified the role of two signaling factors, Nodal and Gdf3, during the early stages of ...
Benjamin Tajer, Mary C Mullins
doaj   +1 more source

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation. [PDF]

open access: yes, 2019
Patient-derived induced pluripotent stem cells (iPSCs) have become a promising resource for exploring genetics of complex diseases, discovering new drugs, and advancing regenerative medicine.
Iacovino, Michelina   +11 more
core  

Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR‐Based β‐Cell Replacement and Treg Immune Modulation Approaches

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease marked by the destruction of pancreatic β‐cells, resulting in lifelong dependence on exogenous insulin. Despite advances in insulin delivery and glucose monitoring technologies, patients remain at risk for acute and long‐term complications, underscoring the need for ...
Tzu‐Min Lin   +5 more
wiley   +1 more source

Sensing oxygen inside and out

open access: yeseLife, 2017
Neuroendocrine cells act as oxygen sensors in animals from fish to humans, but the evolutionary origins of these cells are only just becoming clear.
Maria R Stupnikov, Wellington V Cardoso
doaj   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

open access: yesEquine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez   +6 more
wiley   +1 more source

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