Results 91 to 100 of about 55,791 (279)

A shining starlet: Nematostella vectensis as a model for developmental, regenerative, and comparative biology

Developmental Dynamics, EarlyView.
Abstract The sea anemone, Nematostella vectensis, has been used as a model organism in developmental biology studies for many years. This estuarine species has the notable capacity to regenerate its full body plan from small pieces throughout life. Nematostella have been described as having a great degree of cellular plasticity.
Patrick A. Lewis, Zachary Horowitz, Michael Shribak, Karen Echeverri   +3 more
wiley   +1 more source

Zebrafish ventral gastrula fate map reveals neural crest progenitor domain

Developmental Dynamics, EarlyView.
Abstract Background Fate maps relate progenitor cell positions to later fates and locations of their progeny, revealing early embryonic organization. Previous zebrafish fate maps identified the origin of germ layers and derivative cell fates, but ventral gastrula progenitor domains were not fully resolved. In particular, the neural crest, a multipotent
Elaine E. Kushkowski, Victoria E. Prince
wiley   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

Spatiotemporal transcriptomics reveals the evolutionary history of the endoderm germ layer

Nature, 2014
The concept of germ layers has been one of the foremost organizing principles in developmental biology, classification, systematics and evolution for 150 years (refs 1, 2, 3).
T. Hashimshony, M. Feder, Michal Levin, B. Hall, I. Yanai   +4 more
semanticscholar   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

Characterisation of a novel in vitro model of definitive endoderm development and a novel definitive endoderm gene marker

, 2012
© 2012 Dr. Hwee Ngee GohThe definitive endoderm, one of the primary germ lineages generated during early development, is the forerunner cell population that contributes to the formation of the gastrointestinal and respiratory tract and their associated ...
GOH, HWEE NGEE
core   +1 more source

Pluripotency factors regulate definitive endoderm specification through eomesodermin.

, 2011
Understanding the molecular mechanisms controlling early cell fate decisions in mammals is a major objective toward the development of robust methods for the differentiation of human pluripotent stem cells into clinically relevant cell types.
Arnold, SJ, Brown, S, Trotter, MW, Robertson, EJ, Vallier, L, Teo, AK, Dunn, NR, Ang, LT, Chng, Z   +8 more
core   +2 more sources

Sodium sulfite can reliably induce chemical hypoxia without toxic effects in the model sea anemone species, Exaiptasia diaphana

Limnology and Oceanography: Methods, EarlyView.
Abstract Climate change is accelerating the deoxygenation of aquatic ecosystems, so understanding its effects on biological processes is increasingly critical. An emerging method for inducing hypoxia during experimentation utilizes sodium sulfite (SSI) to scavenge oxygen; however, it remains unclear if hypoxia‐inducing concentrations of SSI are toxic ...
Zhen Qin, Lorenzo Vassura, Bianca A. Parodi, Elise M. J. Laetz   +3 more
wiley   +1 more source

Stem cell engineering of the endoderm: approaches to controlling endoderm induction and differentiation from embryonic stem cells

, 2008
Embryonic stem (ES) cell technology holds promise for curing innumerable human ailments. However, studies of the endoderm germ layer and its derivatives (liver, pancreas, and lung) are lacking.
Parashurama, Natesh
core   +1 more source

Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition

eLife
During the trunk to tail transition the mammalian embryo builds the outlets for the intestinal and urogenital tracts, lays down the primordia for the hindlimb and external genitalia, and switches from the epiblast/primitive streak (PS) to the tail bud as
Anastasiia Lozovska, Ana Casaca, Ana Novoa, Ying-Yi Kuo, Arnon D Jurberg, Gabriel G Martins, Anna-Katerina Hadjantonakis, Moises Mallo   +7 more
doaj   +1 more source