Results 81 to 90 of about 55,791 (279)
Genes & Development, 2015 Wamaitha et al. demonstrate that the transcription factor Gata6 can initiate reprograming of multiple cell types to induced extraembryonic endoderm cells.
Sissy E. Wamaitha +8 more
semanticscholar +1 more source
Mechanical Coupling between Endoderm Invagination and Axis Extension in Drosophila
PLoS Biology, 2015 How genetic programs generate cell-intrinsic forces to shape embryos is actively studied, but less so how tissue-scale physical forces impact morphogenesis. Here we address the role of the latter during axis extension, using Drosophila germband extension
C. Lye +6 more
semanticscholar +1 more source
Developmental Dynamics, EarlyView.Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin +5 more
wiley +1 more source
Insight into Nephrocan function in mouse endoderm patterning [PDF]
, 2021 Endoderm-derived organs as the liver and pancreas are potential targets for regenerative therapies, and so there is great interest in understanding the pathways that regulate the induction and specification of this germ layer. Currently, the knowledge of
Addeo, Martina
core +1 more source
Secretopathies emerge as a new class of neurocristopathies
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira +3 more
wiley +1 more source
Wnt signaling specifies and patterns intestinal endoderm
, 2011 Wnt signaling has been implicated in many developmental processes, but its role in early endoderm development is not well understood. Wnt signaling is active in posterior endoderm as early as E7.5.
Maehr, Rene +7 more
core +1 more source
Lung Endoderm Morphogenesis: Gasping for Form and Function
Annual Review of Cell and Developmental Biology, 2015 The respiratory endoderm develops from a small cluster of cells located on the ventral anterior foregut. This population of progenitors generates the myriad epithelial lineages required for proper lung function in adults through a complex and delicately ...
D. Swarr, E. Morrisey
semanticscholar +1 more source
Zebrafish inversin mutants develop scoliosis in the absence of laterality defects
Developmental Dynamics, EarlyView.Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick +3 more
wiley +1 more source
Fgf signaling negatively regulates Nodal-dependent endoderm induction in zebrafish [PDF]
, 2006 In zebrafish development, Nodal signaling is critical for the induction of endoderm and mesoderm. Three transcription factors downstream of Nodal, Bonnie and Clyde (Bon), Faust (Fau)/Gata5 and Casanova (Cas), are required for endoderm induction. However,
Mizoguchi, Takamasa +3 more
core +1 more source
Vertebrate Endoderm Development and Organ Formation
Annual Review of Cell and Developmental Biology, 2009 The endoderm germ layer contributes to the respiratory and gastrointestinal tracts, and all of their associated organs. Over the past decade, studies in vertebrate model organisms; including frog, fish, chick, and mouse; have greatly enhanced our ...
A. Zorn, James M. Wells
semanticscholar +1 more source