Results 101 to 110 of about 40,613 (248)

Formation of endoderm on EBs, EPLEBs, EBMs.

open access: yes, 2013
A–F. Scanning electron micrographs of EBs (A, D), EBMs (B, E) and EPLEBs (C, F) on days 2.5 (A–C) and 5 (D–F). Arrowheads mark the boundary of the prospective patch of primitive endoderm on EBs on day 2.5 (A) and the prospective endoderm population ...
Mary Familari (319870)   +6 more
core   +1 more source

Primitive to visceral endoderm maturation is essential for mouse epiblast survival beyond implantation

open access: yesiScience
Summary: The implantation of the mouse blastocyst initiates a complex sequence of tissue remodeling and cell differentiation events required for morphogenesis, during which the extraembryonic primitive endoderm transitions into the visceral endoderm ...
Antonia Weberling   +5 more
doaj   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

Xsox17α and -β Mediate Endoderm Formation in Xenopus

open access: yes, 1997
We have isolated two Xenopus relatives of murine Sox17 expressed in gastrula presumptive endoderm. Xsox17α and -β expression can be induced in animal caps by activin, but not by FGF. Ectopic expression of these genes in animal caps induces the expression
Clements, Debbie   +4 more
core   +1 more source

Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR‐Based β‐Cell Replacement and Treg Immune Modulation Approaches

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5476-5491, July 2026.
ABSTRACT Background Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease marked by the destruction of pancreatic β‐cells, resulting in lifelong dependence on exogenous insulin. Despite advances in insulin delivery and glucose monitoring technologies, patients remain at risk for acute and long‐term complications, underscoring the need for ...
Tzu‐Min Lin   +5 more
wiley   +1 more source

Fgf signaling negatively regulates Nodal-dependent endoderm induction in zebrafish

open access: yes, 2006
In zebrafish development, Nodal signaling is critical for the induction of endoderm and mesoderm. Three transcription factors downstream of Nodal, Bonnie and Clyde (Bon), Faust (Fau)/Gata5 and Casanova (Cas), are required for endoderm induction. However,
Mizoguchi, Takamasa   +3 more
core   +1 more source

The Role of Long Non-Coding RNAs in Human Endoderm Differentiation

open access: yesNon-Coding RNA
The human genome sequencing revealed a vast complexity of transcripts, with over 80% of the genome being transcribed into non-coding RNAs. In particular, long non-coding RNAs (lncRNAs) have emerged as critical regulators of various cellular processes ...
Annanda Lyra Ribeiro   +1 more
doaj   +1 more source

endoderm

open access: yes
Citation: 'endoderm' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10659 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

open access: yesEquine Veterinary Journal, Volume 58, Issue 4, Page 970-980, July 2026.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez   +6 more
wiley   +1 more source

The dental plate on bichir pectoral fins: A unique dermal skeletal element bearing individual odontodes with tooth‐like replacement

open access: yesJournal of Anatomy, Volume 249, Issue 1, Page 127-140, July 2026.
Pectoral fins of bichirs encompass the so‐called dental plates – unique dermal skeletal elements with individual odontodes identical to the oral teeth. Abstract The dermal skeleton appeared early in vertebrate evolution in the form of mineralized skin denticles composed of tooth‐like units—odontodes.
Tomáš Suchánek   +2 more
wiley   +1 more source

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