Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Equity and efficiency of carbon tax policies in Switzerland with endogenous energy substitution
Swiss Journal of Economics and StatisticsThe costs and speed of the energy transition are closely linked to the elasticity of substitution between fossil fuels and clean energy sources. Yet, despite its central role, this parameter has been treated as exogenous and constant in numerical studies
Matthias Leuthard
doaj +1 more source
From Solow Model to endogenous economic growth – Romania’s reinsertion into civilization? [PDF]
Informatică economică, 2006 This paper evaluates the determinants of growth in GDP per capita in industrialized countries and the lessons for the Romanian economy. How can Romanian economy grow faster?
Dinu MARIN, Cristian SOCOL
doaj
Multinational Corporations and Endogenous Growth: An Eclectic-Paradigmatic Analysis [PDF]
Endogenous growth theory recently originated in economics. Building on this theory, this chapter conceptualizes the phenomenon of endogenous growth in terms of some new ideas developed in the field of international business (IB).
Sergio Castello, Terutomo Ozawa
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Prognostic analysis of 2-5 cm diameter gastric stromal tumors with exogenous or endogenous growth. [PDF]
World J Surg Oncol, 2023 Lin C +7 more
europepmc +1 more source
Proceedings of the Conference on Emerging Economic Issues in a Globalizing World [PDF]
This paper tests the endogenous relationship between FDI and economic growth using a panel dataset for 23 OECD countries for the period 1975-2004. Following the literature, we treat economic growth and FDI as endogenous variables, and estimate a two ...
Alper Duman +2 more
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Analytical method to derive environmental policy effects in an endogenous growth model with leisure. [PDF]
MethodsX, 2022 Hamaguchi Y, Bhuiyan MA, Rahman MK.
europepmc +1 more source
Endogenous Versus Exogenous Growth Facing a Fertility Shock [PDF]
This paper simulates the impact of a permanent fertility shock on economic growth, using endogenous versus exogenous growth OLG models. An endogenous growth model, with education as the engine of growth, dampens the negative impact of a decline in ...
Medeiros, João
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