Results 101 to 110 of about 52,210 (255)

BCR–ABL1 Drives Transcriptional Reprogramming of Chronic Myeloid Leukemia Cells for Immune Evasion Through C/EBPβ

MedComm, Volume 7, Issue 5, May 2026.
There is global immunosuppression during CML initiation and progression, which is directly driven by BCR–ABL1 expressing CML cells. On one hand, the BCR–ABL1 oncogene drives the differentiation of leukemia cells toward the neutrophil lineage. On the other hand, the oncogene also transcriptionally activates master immune regulators, including arginase ...
Xiaocui Lu, Hui Fang, Yuan Liu, Chang Liu, Xuexiu Fang, Atsuko Matsunaga, Stephanie F. Mori, Ting Zhang, Gavin Wang, George I. Zhou, Miao Yu, Haocheng Ding, Jorge Cortes, Bo Cheng, Tianxiang Hu   +14 more
wiley   +1 more source

Multiple groups of endogenous epsilon-like retroviruses conserved across primates [PDF]

, 2014
Several types of cancer in fish are caused by retroviruses, including those responsible for major outbreaks of disease, such as walleye dermal sarcoma virus and salmon swim bladder sarcoma virus. These viruses form a phylogenetic group often described as
Altschul, Arnaud, Arnold, Baillie, Bannert, Basta, Betancur-R, Brown, Chen, Coffin, Creevey, Gifford, Guindon, Herniou, Jensen-Seaman, Jurka, K. Brown, Katoh, Katzourakis, Keightley, Kent, Krupp, Lepa, Masahito, McCarthy, Meredith, Nellaker, Oja, Paul, Perelman, Polavarapu, R. D. Emes, R. E. Tarlinton, Rice, Rovnak, Shen, Sinzelle, Slater, Smith, Statistics and Information Service, Fisheries and Aquaculture Department, Stocking, Tristem, VanDeValk   +42 more
core   +2 more sources

Xenotransplantation at a Crossroads: Breakthroughs, Challenges, and the Path Forward

Organ Medicine, EarlyView.
Xiaoyu Gan, Jizhang Yu, Jie Wu, Junjie Zong   +3 more
wiley   +1 more source

Upregulation of sphingomyelin and ABCA8 in response to TDP‐43 pathology in amyotrophic lateral sclerosis brain

Brain Pathology, Volume 36, Issue 3, May 2026.
Increases in sphingomyelin in response to TDP‐43 pathology in the disease‐affected motor cortex of amyotrophic lateral sclerosis (ALS) brain. Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by the degeneration of motor neurons and the presence of TAR DNA‐binding protein 43 (TDP‐43 ...
Finula I. Isik, Russell Pickford, Nicolas Dzamko, Kerry‐Anne Rye, Woojin Scott Kim   +4 more
wiley   +1 more source

Evolution and phylogeny of insect endogenous retroviruses

BMC Evolutionary Biology, 2001
Background The genome of invertebrates is rich in retroelements which are structurally reminiscent of the retroviruses of vertebrates. Those containing three open reading frames (ORFs), including an env-like gene, may well be considered as endogenous ...
Pélisson Alain, Terzian Christophe, Bucheton Alain   +2 more
doaj   +1 more source

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles [PDF]

, 1996
Notch is a highly conserved transmembrane protein that is involved in cell fate decisions and is found in organisms ranging from Drosophila to humans. A human homologue of Notch, TAN1, was initially identified at the chromosomal breakpoint of a subset of
Aster, Jon C., Baltimore, David, Hasserjian, Robert P., Pear, Warren S., Scott, Martin L., Sklar, Jeffrey, Soffer, Benny   +6 more
core  

Human endogenous retroviruses [PDF]

APMIS, 2016
Erik, Larsson, Elling, Ulvestad
openaire   +2 more sources

Placental Development and Endogenous Retroviruses

Uirusu, 2016
A placenta as we know now is a relatively new invention in mammals. Data accumulated indicates that a major cell type of the placenta is trophoblast, in which elevated expression of genes derived from various endogenous retroviruses (ERVs) as well as LTR retrotransposons is seen.
Kazuhiko, Imakawa, So, Nakagawa, Kazuya, Kusama   +2 more
openaire   +3 more sources

Transcriptome Analyses of Tumor-Adjacent Somatic Tissues Reveal Genes Co-Expressed with Transposable Elements [PDF]

, 2019
Background: Despite the long-held assumption that transposons are normally only expressed in the germ-line, recent evidence shows that transcripts of transposable element (TE) sequences are frequently found in the somatic cells.
Alberto, Adrian, Chung, Micky, Churchill, Daphnie, Clymer, Cody, Han, Mira V., Jonaid, G. M., Navarro Leija, Omar, Quinton, Sophia, Ross, Austin, Sexton, Corinne E.   +9 more
core   +2 more sources

Persistence pays: how viruses promote host group survival. [PDF]

, 2009
Recently, we have realized that viruses numerically dominate all life. Although viruses are known to affect host survival in populations, this has not been previously evaluated in the context of host group selection.
Villarreal, Luis P
core