Results 101 to 110 of about 445,067 (194)

Endogenous retroviruses in primates [PDF]

open access: yes, 2015
Numerous endogenous retroviruses (ERVs) are found in all mammalian genomes and represent retroviruses which have, by chance, integrated into the germline and are transmitted vertically from parents to offspring.
Brown, Katherine
core  

Artificial Intelligence in Xenotransplantation: A Prioritized Roadmap for Early Clinical Translation, Opportunities and Challenges

open access: yesXenotransplantation, Volume 33, Issue 5, September/October 2026.
ABSTRACT Xenotransplantation represents a potential solution to the persistent global organ shortage, yet its clinical application remains stalled by complex immunologic responses, coagulation dysregulation, species‐specific biology, and infectious risks.
Kasra Shirini   +7 more
wiley   +1 more source

Beyond pathogens: the intriguing genetic legacy of endogenous retroviruses in host physiology

open access: yesFrontiers in Cellular and Infection Microbiology
The notion that viruses played a crucial role in the evolution of life is not a new concept. However, more recent insights suggest that this perception might be even more expansive, highlighting the ongoing impact of viruses on host evolution. Endogenous
Amanda Lopes da Silva   +8 more
doaj   +1 more source

Endogenous retroviruses and cancer

open access: yes, 2010
Endogenous retroviruses (ERVs) abound in avian and mammalian genomes, including humans, as a result of germline infections by exogenous retroviruses. Most ERVs are defective for production of infectious virus.
Sanchita Bhadra   +9 more
core   +1 more source

Role of endogenous retroviruses in murine SLE

open access: yes, 2010
Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by B cell hyperactivity leading to the production of various autoantibodies and subsequent development of glomerulonephritis, i.e. lupus nephritis.
Baudino, Lucie Clementine   +9 more
core   +1 more source

Characterising and Mapping Porcine Endogenous Retroviruses (PERVs) [PDF]

open access: yes, 2001
The initial focus of this PhD project was on comparative gene mapping. Comparative gene mapping is facilitated by consensus PCR primers which amplify homologous gene fragments in many species.
Lee, Jun Heon
core  

Endogenous retroviruses in primates [PDF]

open access: yes
Numerous endogenous retroviruses (ERVs) are found in all mammalian genomes and represent retroviruses which have, by chance, integrated into the germline and are transmitted vertically from parents to offspring.
Brown, Katherine
core   +2 more sources

Cell entry and exit of porcine endogenous retrovirus A: receptors and release inhibitor [PDF]

open access: yes, 2010
Following the discovery that porcine endogenous retrovirus (PERV) can infect human cells, the potential risk of a zoonotic infection by PERV has been a major obstacle in the xenotransplantation field.
Mattiuzzo, G.
core  

Interplay between endogenous and exogenous human retroviruses

open access: yes, 2023
In humans, retroviruses thrive more as symbionts than as parasites. Apart from the only two modern exogenous human retroviruses (human T-cell lymphotropic and immunodeficiency viruses; HTLV and HIV, respectively), ~8% of the human genome is occupied by ...
Kyriakou, E., Magiorkinis, G.
core  

Porcine endogenous retroviruses in xenotransplantation

open access: yesNephrology Dialysis Transplantation
ABSTRACT Xenotransplantation using pig cells, tissues or organs is under development to alleviate the shortage of human donor organs. Meanwhile, remarkably long survival times of pig organs in non-human primates have been reported, as well as the functionality of pig kidneys and hearts in brain-dead humans.
openaire   +2 more sources

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