Transcriptional Regulation of Endogenous Retroviruses and Their Misregulation in Human Diseases
International Journal of Molecular Sciences, 2022 Endogenous retroviruses (ERVs), deriving from exogenous retroviral infections of germ line cells occurred millions of years ago, represent ~8% of human genome.
Qian Zhang +3 more
semanticscholar +1 more source
Endogenous Retroviruses and Placental Evolution, Development, and Diversity
Cells, 2022 The main roles of placentas include physical protection, nutrient and oxygen import, export of gasses and fetal waste products, and endocrinological regulation. In addition to physical protection of the fetus, the placentas must provide immune protection
K. Imakawa +6 more
semanticscholar +1 more source
Origin and Deep Evolution of Human Endogenous Retroviruses in Pan-Primates
Viruses, 2022 Human endogenous retroviruses (HERVs) are viral “fossils” in the human genome that originated from the ancient integration of exogenous retroviruses. Although HERVs have sporadically been reported in nonhuman primate genomes, their deep origination in ...
Yian Li, Guojie Zhang, Jie Cui
semanticscholar +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Xenotransplantation, EarlyView., 2020 Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Complete genome sequences of two feline Leukemia virus subgroup B isolates with novel recombination sites [PDF]
, 2013 It is generally accepted that all primary isolates of feline leukemia virus (FeLV) contain a subgroup A virus (FeLV-A) that is essential for transmission.
Bae +12 more
core +1 more source
PLoS Pathogens, 2007 Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections of the host germline transmitted vertically from generation to generation. It is hypothesized that some ERVs are used by the host as restriction factors to block the infection ...
Frederick Arnaud +14 more
doaj +1 more source
Endogenous retroviruses shape pluripotency specification in mouse embryos
Science AdvancesThe smooth and precise transition from totipotency to pluripotency is a key process in embryonic development, generating pluripotent stem cells capable of forming all cell types.
Sergio de la Rosa +4 more
semanticscholar +1 more source
Multiple groups of endogenous epsilon-like retroviruses conserved across primates [PDF]
, 2014 Several types of cancer in fish are caused by retroviruses, including those responsible for major outbreaks of disease, such as walleye dermal sarcoma virus and salmon swim bladder sarcoma virus. These viruses form a phylogenetic group often described as
Altschul +42 more
core +2 more sources
Morc3 silences endogenous retroviruses by enabling Daxx-mediated histone H3.3 incorporation
Nature Communications, 2021 Endogenous retroviruses (ERVs) comprise a significant portion of mammalian genomes. Although specific ERV loci feature regulatory roles for host gene expression, most ERV integrations are transcriptionally repressed by Setdb1-mediated H3K9me3 and DNA ...
Sophia Groh +10 more
semanticscholar +1 more source
Potential benefits and risks of clinical xenotransplantation [PDF]
, 2012 The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core +2 more sources