Results 121 to 130 of about 10,232 (247)

Genetically Engineered Phages: a Review of Advances over the Last Decade [PDF]

, 2016
Summary: Soon after their discovery in the early 20th century, bacteriophages were recognized to have great potential as antimicrobial agents, a potential that has yet to be fully realized.
Alberts B, Bruynoghe R, CDC, Chan LY, d'Herelle F, d'Hérelle F, d'Hérelle F, Dever LA, Górski A, Lodish H, Makarova KS, Miyake H, Murphy MP, Rose T, Summers WC, Vaara M, Weber-Dabrowska B, WHO   +17 more
core   +1 more source

Dual glycosylation of wall teichoic acid modulates the O‐antigen pattern and virulence in serovar 4b Listeria monocytogenes

mLife, Volume 4, Issue 6, Page 638-650, December 2025.
Abstract Among the 14 serovars of Listeria monocytogenes (Lm), serovar 4b strains are the most predominant isolates linked to human listeriosis outbreaks‐a phenotype associated with their unique wall teichoic acid (WTA) decorated with galactose (Gal) and glucose (Glu).
Hao Yao, Yuting Wang, Ruochen Wang, Zhengnan Dong, Zhenhua Wu, Luyong Wang, Yuelan Yin, Xin'an Jiao   +7 more
wiley   +1 more source

LysJEP8: A promising novel endolysin for combating multidrug‐resistant Gram‐negative bacteria

Microbial Biotechnology
Antimicrobial resistance (AMR) is an escalating global health crisis, driven by the overuse and misuse of antibiotics. Multidrug‐resistant Gram‐negative bacteria, such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, are ...
J. Carratalá, N. Ferrer-Miralles, E. Garcia-Fruitós, A. Arís   +3 more
semanticscholar   +1 more source

Listeria bacteriophage peptidoglycan hydrolases feature high thermoresistance and reveal increased activity after divalent metal cation substitution [PDF]

, 2018
The ability of the bacteriophage-encoded peptidoglycan hydrolases (endolysins) to destroy Gram-positive bacteria from without makes these enzymes promising antimicrobials.
Loessner, Martin, Schmelcher, Mathias, Waldherr, Florian   +2 more
core  

SNAC‐Tag Integration Into NPN Platform Facilitates Efficient Purification of Recombinant Proteins From Nicotiana benthamiana

Plant Biotechnology Journal, Volume 24, Issue 1, Page 87-89, January 2026.
Hui‐Xin Meng, Hai‐Ping Diao, Jin‐Hao Sun, Shi‐Yu Ren, Xue‐Jiao Xu, Yong‐Feng Guo, Shi‐Jian Song   +6 more
wiley   +1 more source

Antibiotic Persister Cells in Acinetobacter baumannii: Overview of Molecular Mechanisms and Removal Strategies

Environmental Microbiology, Volume 27, Issue 11, November 2025.
Antibiotic persister cells in Acinetobacter baumannii: review of the molecular mechanisms involved in this physiology, such as toxin/antitoxin, second messengers, SOS response, PAA or membranes; and elimination strategies such as antibiotics or phages.
Delphine Vergoz, Emmanuelle Dé, Corinne Loutelier‐Bourhis, Stéphane Alexandre   +3 more
wiley   +1 more source

Enhanced antibacterial activity of Acinetobacter baumannii bacteriophage ØABP-01 endolysin (LysABP-01) in combination with colistin

Frontiers in Microbiology, 2016
Endolysins are lytic enzymes produced by bacteriophages with their ability to degrade the cell wall of bacterial hosts. Endolysin (LysABP-01) from A. baumannii bacteriophage ØABP-01 was cloned, overexpressed and characterized.
Rapee Thummeepak, Thawatchai Kitti, Duangkamol Kunthalert, Duangkamol Kunthalert, Sutthirat Sitthisak, Sutthirat Sitthisak   +5 more
doaj   +1 more source

Influence of Lipopolysaccharide-Interacting Peptides Fusion with Endolysin LysECD7 and Fatty Acid Derivatization on the Efficacy against Acinetobacter baumannii Infection In Vitro and In Vivo

Viruses
Acinetobacter baumannii has developed multiple drug resistances, posing a significant threat to antibiotic efficacy. LysECD7, an endolysin derived from phages, could be a promising therapeutic agent against multi-drug resistance A. baumannii.
Xiaowan Li, Wenwen Shangguan, Xiaoqian Yang, Xiaoyue Hu, Yanan Li, Wenjie Zhao, Meiqing Feng, Jun Feng   +7 more
semanticscholar   +1 more source

Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection [PDF]

, 2017
Objectives In the light of increasing drug resistance in Staphylococcus aureus, bacteriophage endolysins [peptidoglycan hydrolases (PGHs)] have been suggested as promising antimicrobial agents.
Becker, Stephen C., Dong, Shengli, Donovan, David M., Eichenseher, Fritz, Eugster, Marcel R., Foster-Frey, Juli, Hanke, Daniela C., Lee, Jean C., Loessner, Martin J., Nelson, Daniel C., Pritchard, David G., Schmelcher, Mathias, Shen, Yang   +12 more
core   +1 more source

Bacteriophage vB_SepP_134 and Endolysin LysSte_134_1 as Potential Staphylococcus-Biofilm-Removing Biological Agents

Viruses
Bacteria of the genus Staphylococcus are significant challenge for medicine, as many species are resistant to multiple antibiotics and some are even to all of the antibiotics we use.
N. Golosova, A. Matveev, Nina V. Tikunova, Y. Khlusevich, Yulia N. Kozlova, Vera V. Morozova, I. Babkin, Tatiana Ushakova, E. Zhirakovskaya, E. A. Panina, E. Ryabchikova, A. Tikunov   +11 more
semanticscholar   +1 more source