Results 111 to 120 of about 8,598 (217)

Phages Preying on Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis: Past, Present and Future [PDF]

, 2014
Many bacteriophages (phages) have been widely studied due to their major role in virulence evolution of bacterial pathogens. However, less attention has been paid to phages preying on bacteria from the Bacillus cereus group and their contribution to the ...
Ackermann, Ackermann, Afrikian, Ahmed, Annika Gillis, Aronson, Azizbekian, Barsomian, Barylski, Bravo, Brown, Buck, Casjens, Casjens, Ciuca, Clements, Cohen, Coman, Cowles, Delbrück, Dong, Duckworth, D’Herelle, Edintsov, El-Arabi, Farrar, Fouet, Fruciano, Fulmer, Gaal, Green, Griffiths, Grose, He, Heierson, Hendrix, Hendrix, Hulo, Inal, Inal, Jacques Mahillon, Jensen, Jones, Kanda, Kanda, Kanda, Kanda, Kellenberger, Khachatrian, King, Koretskaia, Koretskaia, Koroleva, Landén, Lavigne, Lecadet, Lecadet, Lee, Lemos Monteiro, Lemos Monteiro, Lewis, Liao, Loessner, Mahillon, Maroun, Maughan, Mccloy, Moumen, Nagy, Nakamura, Oksanen, Perlak, Pogosbekova, Priest, Raiga, Rasko, Redondo, Reynolds, Ruhfel, Sansinenea, Serwer, Shin, Sorokin, Sozhamannan, Stamatin, Stamatin, Stamatin, Stepanov, Stiube, Stiube, Sullivan, Swanson, Thorne, Thorne, Thorne, Thorne, Tikhonenko, Tikhonenko, Tikhonenko, Ting, Toschkov, Turnbull, Tyeryar, Verheust, Verheust, Walter, Watanabe, Yelton, Yelton   +108 more
core   +1 more source

Novel endolysin

, 2018
The present invention relates to a polypeptide with endolysin activity and amino acid sequences according to SEQ ID No. 1 and fragments or derivatives thereof. Moreover, the present invention relates to nucleic acid molecules encoding said polypeptide, vectors comprising said nucleic acid molecules and host cells comprising either said nucleic acid ...
Oliveira, Hugo Alexandre Mendes, Azeredo, Joana   +1 more
openaire   +1 more source

Enhanced antibacterial activity of Acinetobacter baumannii bacteriophage ØABP-01 endolysin (LysABP-01) in combination with colistin

Frontiers in Microbiology, 2016
Endolysins are lytic enzymes produced by bacteriophages with their ability to degrade the cell wall of bacterial hosts. Endolysin (LysABP-01) from A. baumannii bacteriophage ØABP-01 was cloned, overexpressed and characterized.
Rapee Thummeepak, Thawatchai Kitti, Duangkamol Kunthalert, Duangkamol Kunthalert, Sutthirat Sitthisak, Sutthirat Sitthisak   +5 more
doaj   +1 more source

Effective Removal of Staphylococcal Biofilms by the Endolysin LysH5

PLoS ONE, 2014
Staphylococcal biofilms are a major concern in both clinical and food settings because they are an important source of contamination. The efficacy of established cleaning procedures is often hindered due to the ability of some antimicrobial compounds to induce biofilm formation, and to the presence of persister cells, a small bacterial subpopulation ...
Diana Gutiérrez, Patricia Ruas-Madiedo, Beatriz Martínez, Ana Rodríguez, Pilar García   +4 more
openaire   +5 more sources

Bacteriophage Endolysins as a Novel Class of Antibacterial Agents

Experimental Biology and Medicine, 2006
Endolysins are double-stranded DNA bacteriophage-encoded peptidoglycan hydrolases produced in phage-infected bacterial cells toward the end of the lytic cycle. They reach the peptidoglycan through membrane lesions formed by holins and cleave it, thus, inducing lysis of the bacterial cell and enabling progeny virions to be released. Endolysins are also
Jan, Borysowski, Beata, Weber-Dabrowska, Andrzej, Górski   +2 more
openaire   +2 more sources

A new phage endolysin as a powerful tool to detect and kill Paenibacillus larvae [PDF]

, 2016
American foulbrood (AFB) is an infection caused by Paenibacillus larvae (P. larvae), a Gram-positive spore forming bacteria. This disease occurs in honeybee larvae, when spores germinate and proliferate in their midgut and subsequently penetrate into the
Azeredo, Joana, Melo, Luís Daniel Rodrigues, Oliveira, Ana Cristina Afonso, Santos, Sílvio Roberto Branco   +3 more
core  

Genetically modified bacteriophages [PDF]

, 2016
Phages or bacteriophages, viruses that infect and replicate inside bacteria, are the most abundant microorganisms on earth. The realization that antibiotic resistance poses a substantial risk to the world’s health and global economy is revitalizing phage
Grigonyte, Aurelija M., Jaramillo, Alfonso, MacDonald, Paul, Sagona, Antonia P.   +3 more
core   +1 more source

Characterization of Clostridium perfringens Phage Endolysin PlyDolk21

Antibiotics
Background: Clostridium perfringens is a significant cause of food poisoning. Broad-spectrum antibiotics, commonly used to control C. perfringens, are becoming less effective due to the rise of antibiotic-resistant strains, necessitating alternative control strategies. Methods: A C.
Suyoung Seo, Bokyung Son, Minsuk Kong
openaire   +2 more sources

Extraction, Purification and Therapeutic Use of Bacteriophage Endolysin against Multi-Drug Resistant Staphylococcus aureus: in-vivo and in-vitro study

Journal of Contemporary Medical Sciences, 2018
Objectives: Isolation of endolysin from Staphylococcus aureus bacteriophages, and administering them systemic In vivo lab animal and measure the therapeutic efficacy as well as evaluation of their biosafety. Method: This study was performed from March
Mohammed R. Ali, Ahmed S. Abdulamir, Shurooq R. Kadhim   +2 more
doaj  

Antibacterial activity of recombinant endolysin LysNOVA-I against growing/non-growing and planktonic/biofilm cultures of Staphylococcus aureus strains

Journal of Global Antimicrobial Resistance
: Objective: Bacteriophage-encoded endolysins have emerged as novel antibacterial strategies against antibiotic-resistant bacteria. We identified a bacteriophage-derived conserved sequence encoding an endolysin specific to Staphylococcus aureus.
Carla Rivero, Melina M.B. Martínez, Nicole G. Picinin, Eduardo G. Martins, Claudio Paolazzi, Alejandra Capozzo, Denise da Silva Oliveira, Johana Becerra, Benedito M. dos Santos, Lucio H.G. de Freitas-Junior, Andrea Balan, Nilton Lincopan, Rita de Cassia Café Ferreira, Luis Carlos de Souza Ferreira, Leticia Verónica Bentancor   +14 more
doaj   +1 more source