Lysis-deficient phages as novel therapeutic agents for controlling bacterial infection [PDF]
BMC Microbiology, 2011 Background Interest in phage therapy has grown over the past decade due to the rapid emergence of antibiotic resistance in bacterial pathogens. However, the use of bacteriophages for therapeutic purposes has raised concerns over the potential for immune ...
Kempashanaiah Nanjundappa +7 more
doaj +4 more sources
Modulation of Endolysin LysECD7 Bactericidal Activity by Different Peptide Tag Fusion
Biomolecules, 2020 The use of recombinant endolysins is a promising approach for antimicrobial therapy capable of counteracting the spread of antibiotic-resistant strains.
Nataliia P. Antonova +16 more
doaj +3 more sources
Formation of therapeutic phage cocktail and endolysin to highly multi-drug resistant Acinetobacter baumannii: in vitro and in vivo study [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Phage therapy is a potential alternative treatment for infections caused by Acinetobacter baumannii, a significant nosocomial pathogen, which has evolved resistance to almost all conventional antimicrobial drugs in poor hygiene and ...
Hayder Nsaif Jasim +2 more
doaj +1 more source
Phage Endolysins: Advances in the World of Food Safety
Cells, 2023 As antimicrobial resistance continues to escalate, the exploration of alternative approaches to safeguard food safety becomes more crucial than ever. Phage endolysins are enzymes derived from phages that possess the ability to break down bacterial cell ...
Amina Nazir +3 more
doaj +1 more source
2.PHAGE COCKTAILS AGAINST HIGHLY MULTI-DRUG RESISTANT ACINETOBACTER BAUMANII
The Iraqi Journal of Medical Sciences, 2019 Background:Phage therapy is a potential alternative treatment for infections caused by many bacterial species such as Acinetobacter baumannii (A.
Hayder N. Jasim, Ahmad S. Abdul-Ameer
doaj +6 more sources
Phage-derived peptidoglycan degrading enzymes: challenges and future prospects for in vivo therapy [PDF]
, 2018 Peptidoglycan degrading enzymes are of increasing interest as antibacterial agents, especially against multi-drug resistant pathogens. Herein we present a review about the biological features of virion-associated lysins and endolysins, phage-derived ...
Azeredo, Joana +2 more
core +2 more sources
PHAGE COCKTAILS AGAINST HIGHLY MULTI-DRUG RESISTANT ACINETOBACTER BAUMANII
The Iraqi Journal of Medical Sciences, 2018 Background:Phage therapy is a potential alternative treatment for infections caused by many bacterial species such as Acinetobacter baumannii (A.
Hayder Jasim, Ahmad Abdul-Ameer
doaj +1 more source
Engineered endolysin-based "artilysins" to combat multidrug-resistant gram-negative pathogens [PDF]
, 2014 The global threat to public health posed by emerging multidrug-resistant bacteria in the past few years necessitates the development of novel approaches to combat bacterial infections.
Brenner +40 more
core +4 more sources
Prophage-triggered membrane vesicle formation through peptidoglycan damage in Bacillus subtilis [PDF]
, 2017 Bacteria release membrane vesicles (MVs) that play important roles in various biological processes. However, the mechanisms of MV formation in Gram-positive bacteria are unclear, as these cells possess a single cytoplasmic membrane that is surrounded by ...
Cárcamo-Oyarce Gerardo +11 more
core +1 more source
Structure and activity of ChiX, a peptidoglycan hydrolase required for chitinase secretion by Serratia marcescens [PDF]
, 2018 The Gram‐negative bacterium Serratia marcescens secretes a number of proteins that are involved in extracellular chitin degradation. This so‐called chitinolytic machinery includes three types of chitinase enzymes and a lytic polysaccharide monooxygenase.
Adam Lodge +48 more
core +2 more sources