Results 1 to 10 of about 919,118 (97)

Construction and Characterization of the Novel Engineered Endolysin ALC005: A New Alternative Antimicrobial Against Riemerella anatipestifer [PDF]

Microorganisms
The increasing serotypic diversity and multidrug resistance of Riemerella anatipestifer pose a serious threat to the poultry industry, necessitating novel antimicrobial agents.
Hongmei Chen, Nansong Jiang, Weiwei Wang, Qizhang Liang, Qiuling Fu, Rongchang Liu, Chunhe Wan, Yu Huang, Guanghua Fu, Longfei Cheng   +9 more
doaj   +2 more sources

Modulation of Endolysin LysECD7 Bactericidal Activity by Different Peptide Tag Fusion

Biomolecules, 2020
The use of recombinant endolysins is a promising approach for antimicrobial therapy capable of counteracting the spread of antibiotic-resistant strains.
Nataliia P. Antonova, Daria V. Vasina, Evgeny O. Rubalsky, Mikhail V. Fursov, Alina S. Savinova, Igor V. Grigoriev, Evgeny V. Usachev, Natalia V. Shevlyagina, Vladimir G. Zhukhovitsky, Vadim U. Balabanyan, Vasiliy D. Potapov, Andrey V. Aleshkin, Valentine V. Makarov, Sergey M. Yudin, Alexander L. Gintsburg, Artem P. Tkachuk, Vladimir A. Gushchin   +16 more
doaj   +3 more sources

Formation of therapeutic phage cocktail and endolysin to highly multi-drug resistant Acinetobacter baumannii: in vitro and in vivo study [PDF]

Iranian Journal of Basic Medical Sciences, 2018
Objective(s): Phage therapy is a potential alternative treatment for infections caused by Acinetobacter baumannii, a significant nosocomial pathogen, which has evolved resistance to almost all conventional antimicrobial drugs in poor hygiene and ...
Hayder Nsaif Jasim, Rand Riadh Hafidh, Ahmed Sahib Abdulamir   +2 more
doaj   +1 more source

2.PHAGE COCKTAILS AGAINST HIGHLY MULTI-DRUG RESISTANT ACINETOBACTER BAUMANII

The Iraqi Journal of Medical Sciences, 2019
Background:Phage therapy is a potential alternative treatment for infections caused by many bacterial species such as Acinetobacter baumannii (A.
Hayder N. Jasim, Ahmad S. Abdul-Ameer
doaj   +6 more sources

Phage Endolysins: Advances in the World of Food Safety

Cells, 2023
As antimicrobial resistance continues to escalate, the exploration of alternative approaches to safeguard food safety becomes more crucial than ever. Phage endolysins are enzymes derived from phages that possess the ability to break down bacterial cell ...
Amina Nazir, Xiaohui Xu, Yuqing Liu, Yibao Chen   +3 more
doaj   +1 more source

PHAGE COCKTAILS AGAINST HIGHLY MULTI-DRUG RESISTANT ACINETOBACTER BAUMANII

The Iraqi Journal of Medical Sciences, 2018
Background:Phage therapy is a potential alternative treatment for infections caused by many bacterial species such as Acinetobacter baumannii (A.
Hayder Jasim, Ahmad Abdul-Ameer
doaj   +1 more source

Lysis-deficient phages as novel therapeutic agents for controlling bacterial infection

BMC Microbiology, 2011
Background Interest in phage therapy has grown over the past decade due to the rapid emergence of antibiotic resistance in bacterial pathogens. However, the use of bacteriophages for therapeutic purposes has raised concerns over the potential for immune ...
Kempashanaiah Nanjundappa, Hariharan Sukumar, Rajagopalan Sanjeev, Sundarrajan Sudarson, Paul Vivek, Padmanabhan Sriram, Sriram Bharathi, Ramachandran Janakiraman   +7 more
doaj   +1 more source

Endolysin Expression, Purification and Activity Determination by Zymography

Bio-Protocol, 2014
Endolysins are peptidoglycan-degrading (muralytic) enzymes produced by many bacteriophages for cell lysis of the host bacterium. The enzymatic activity of muralytic enzymes can be assayed qualitatively using a zymogram containing incorporated ...
Alexander Westbye, Paul Fogg, John Beatty   +2 more
doaj   +1 more source

A bacteriophage endolysin that eliminates intracellular streptococci

eLife, 2016
PlyC, a bacteriophage-encoded endolysin, lyses Streptococcus pyogenes (Spy) on contact. Here, we demonstrate that PlyC is a potent agent for controlling intracellular Spy that often underlies refractory infections.
Yang Shen, Marilia Barros, Tarek Vennemann, D Travis Gallagher, Yizhou Yin, Sara B Linden, Ryan D Heselpoth, Dennis J Spencer, David M Donovan, John Moult, Vincent A Fischetti, Frank Heinrich, Mathias Lösche, Daniel C Nelson   +13 more
doaj   +1 more source

Saccharomyces cerevisiae secretion of recombinant bacteriophage endolysin LysKB317 inhibits Limosilactobacillus fermentum in corn mash fermentation [PDF]

Biofuel Research Journal
This study investigated the secretion of endolysin LysKB317 integrated into the HO locus of Saccharomyces cerevisiae strain NRRL Y-2034 to enable the yeast to simultaneously perform ethanol fermentation and control bacterial contaminants frequently ...
Shao-Yeh Lu, Maulik Patel, Ronald Hector, Michael Bowman, Christopher Skory   +4 more
doaj   +1 more source