Yersinia enterocolitica-Specific Infection by Bacteriophages TG1 and ϕR1-RT Is Dependent on Temperature-Regulated Expression of the Phage Host Receptor OmpF [PDF]
, 2016 Bacteriophages present huge potential both as a resource for developing novel tools for bacterial diagnostics and for use in phage therapy. This potential is also valid for bacteriophages specific for Yersinia enterocolitica. To increase our knowledge of
Chen, Shu +14 more
core +1 more source
Developing Innolysins against Campylobacter jejuni using a novel prophage receptor-binding protein [PDF]
, 2021 Campylobacter contaminated poultry remains the major cause of foodborne gastroenteritis worldwide, calling for novel antibacterials. We previously developed the concept of Innolysin composed of an endolysin fused to a phage receptor binding protein (RBP)
Briers, Yves +9 more
core +2 more sources
Novel approaches to combat bacterial biofilms. [PDF]
, 2014 International audienceBiofilms formed by pathogenic bacteria and fungi are associated with a wide range of diseases, from device-related infections (such as catheters or prosthetic joints) to chronic infections occurring on native tissues (such as lung ...
Beloin, Christophe +3 more
core +5 more sources
Cellular and Enzymatic Determinants Impacting the Exolytic Action of an Anti-Staphylococcal Enzybiotic [PDF]
, 2023 Bacteriophage endolysins are bacteriolytic enzymes that have been explored as potential weapons to fight antibiotic-resistant bacteria. Despite several studies support the application of endolysins as enzybiotics, detailed knowledge on cellular and ...
Gouveia, Ana +3 more
core +1 more source
Characterization and genome sequencing of a Citrobacter freundii phage CfP1 harboring a lysin active against multidrug-resistant isolates [PDF]
, 2016 Citrobacter spp., although frequently ignored, is emerging as an important nosocomial bacterium able to cause various superficial and systemic life-threatening infections.
AE Darling +59 more
core +3 more sources
Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation
Microbial Biotechnology, Volume 19, Issue 4, April 2026.Bacterial membrane vesicle biomedical applications. ABSTRACT Bacterial Extracellular Vesicles (bEVs) are lipid (single‐ or double‐bilayer) nanostructures secreted by virtually all bacteria that play fundamental roles in intercellular communication and have emerged as powerful, multifunctional tools in biomedicine. Their intrinsic ability to encapsulate
Alejandro Arce‐Rodríguez +2 more
wiley +1 more source
Bacteriophage Therapy: Current Strategies and Future Perspectives
MedComm, Volume 7, Issue 3, March 2026.This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou +7 more
wiley +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.ABSTRACT In the U.S., bovine milk is processed using thermal pasteurization to ensure microbial safety. However, this process alters the structure of heat‐sensitive bioactive proteins associated with the functional benefits of raw milk, including antimicrobial, immunomodulatory, and antioxidant proteins.
Rudy Sykora +5 more
wiley +1 more source
A new phage endolysin as a powerful tool to detect and kill Paenibacillus larvae [PDF]
, 2016 American foulbrood (AFB) is an infection caused by Paenibacillus larvae (P. larvae), a Gram-positive spore forming bacteria. This disease occurs in honeybee larvae, when spores germinate and proliferate in their midgut and subsequently penetrate into the
Azeredo, Joana +3 more
core
Guidelines to reach high-quality purified recombinant proteins [PDF]
, 2018 The final goal in recombinant protein production is to obtain high-quality pure protein samples. Indeed, the successful downstream application of a recombinant protein depends on its quality.
Domingues, Lucília +1 more
core +1 more source