Results 161 to 170 of about 10,232 (247)

Inhaled endolysin therapy for bacterial infections

, 2023
Antimicrobial peptides and proteins (APPs) are becoming increasingly important in targeting multidrug-resistant (MDR) bacteria. Inhalation delivery of these agents can be an effective treatment of respiratory infections owing to the high local drug concentration in the lungs.
openaire   +1 more source

Exploring the therapeutic potential of endolysin CD27L_EAD against Clostridioides difficile infection.

International Journal of Antimicrobial Agents
Clostridioides difficile has emerged as a major cause of life-threatening diarrheal disease. Conventional antibiotics used in current standards of care exacerbate the emergence of antibiotic-resistant strains and pose a risk of recurrent C.
Youngjin Cho, Kyungah Park, Jeongseok Park, Jieun An, Heejoon Myung, Hyunjin Yoon   +5 more
semanticscholar   +1 more source

Endolysins are hidden out there

, 2018
Trabajo presentado en el 2nd International Symposium on Antimicrobial Hydrolytic Enzymes, celebrado en Nueva York (Estados Unidos), del 6 al 8 de noviembre de 2018 Peer ...
Gutiérrez, Diana, Weiss Nielsen, Martin, García Suárez, María Pilar, Martínez, Manuel, Rodríguez González, Ana   +4 more
openaire   +1 more source

Molecular Dissection of Phage Endolysin [PDF]

Journal of Biological Chemistry, 2014
Amol Arunrao Pohane, Himanshu Joshi, Vikas Jain   +2 more
openaire   +1 more source

Functional and structural in silico characterization of endolysins encoded by the novel lytic coliphage ASEC2201 isolated from a wastewater treatment plant

Cleaner Water
Background: The increasing prevalence of multidrug-resistant (MDR) Escherichia coli in environmental and clinical settings necessitates alternative antibacterial strategies beyond conventional antibiotics.
Sudhaker Padmesh, Humaira Saeed, Aditi Singh, Manodeep Sen   +3 more
doaj   +1 more source

A new phage endolysin as a powerful tool to detect and kill Paenibacillus larvae [PDF]

, 2016
American foulbrood (AFB) is an infection caused by Paenibacillus larvae (P. larvae), a Gram-positive spore forming bacteria. This disease occurs in honeybee larvae, when spores germinate and proliferate in their midgut and subsequently penetrate into the
Azeredo, Joana, Melo, Luís Daniel Rodrigues, Oliveira, Ana Cristina Afonso, Santos, Sílvio Roberto Branco   +3 more
core  

Genome sequence of the temperate bacteriophage PH10 from Streptococcus oralis [PDF]

, 2018
Exponential growing cultures of Streptococcus oralis strain OMZ 1038, isolated from human supragingival dental plaque, were found to release a bacteriophage (designated PH10) upon treatment with mitomycin C. The complete genome sequence of phage PH10 was
van der Ploeg, Jan
core  

The PlySs9 endolysin and its amidase subdomain reveal potential roles in the treatment of Gram-positive bovine mastitis [PDF]

, 2019
Lavigne, Rob, Linden, Sara B, Meyer, Evelyne, Nelson, Daniel C, Vander Elst, Niels   +4 more
core   +1 more source

Clinical implementation of endolysins targeting gram-positive bacteria points toward a combination strategy with standard-of-care antibiotics: a selective review. [PDF]

Eur J Med Res
Vander Elst N.
europepmc   +1 more source

Recent Advances in Endolysin Engineering. [PDF]

Antibiotics (Basel)
Aitken M, Abeysekera G, Billington C, Dobson RCJ.   +3 more
europepmc   +1 more source