Results 211 to 220 of about 10,232 (247)

Biological characterization and genomic analysis of the newly discovered mycobacteriophage WST1. [PDF]

BMC Microbiol
Tan X, Zhang X, He Z, Luo Z, An N, Ye K, Ke D, Li Y, Zeng J.   +8 more
europepmc   +1 more source

Engineering an antimicrobial chimeric endolysin that targets the phytopathogen Pseudomonas syringae pv. actinidiae. [PDF]

J Biol Chem
Warring SL, Sisson HM, Randall G, Grimon D, Dams D, Gutiérrez D, Fellner M, Fagerlund RD, Briers Y, Jackson SA, Fineran PC.   +10 more
europepmc   +1 more source

Genome Sequences of Alatato and Audell, two Phages that infect <i>Arthrobacter globiformis</i> and have Different Life Cycles. [PDF]

MicroPubl Biol
Robinson SE, Stanford E, Abraham S, Aguilera R, Anantoji NS, Barillas M, Barstys R, Benson E, Boucher KR, Chacko AM, Chandrakanth N, Chau A, Chen A, Coleman J, Duc LT, Godfrey O, Hoang SN, Kethamreddy M, Kumar N, Le BN, Lin GT, Nguyen KB, Pandit M, Shah KD, Sharma M, Singh S, Smith J, Thomas LV, Varghese A, Wells I, Pollenz RS.   +30 more
europepmc   +1 more source

Articles of Significant Interest in This Issue. [PDF]

Appl Environ Microbiol
europepmc   +1 more source

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Crystal structure of the engineered endolysin mtEC340M

Acta Crystallographica Section F Structural Biology Communications, 2023
Endolysins produced by bacteriophages play essential roles in the release of phage progeny by degrading the peptidoglycan layers of the bacterial cell wall. Bacteriophage-encoded endolysins have emerged as a new class of antibacterial agents to combat surging antibiotic resistance.
Jee-Min Wang, Seung-Hyeon Seok, Won-Su Yoon, Ji-Hun Kim, Min-Duk Seo   +4 more
openaire   +2 more sources

Bacteriophage endolysins: applications for food safety

Current Opinion in Biotechnology, 2016
Bacteriophage endolysins (peptidoglycan hydrolases) have emerged as a new class of antimicrobial agents useful for controlling bacterial infection or other unwanted contaminations in various fields, particularly in the light of the worldwide increasing frequency of drug-resistant pathogens.
Mathias, Schmelcher, Martin J, Loessner
openaire   +2 more sources

Enzymatic property and stabilization mechanism of LysBT1, a novel polyextremotolerant endolysin with a C-terminal S-layer homology domain

Applied and Environmental Microbiology
Phage-encoded endolysins are getting increasing attention because of their potential to serve as alternative antimicrobials to combat antibiotic-resistant bacteria.
Yu Li, Ke Luo, Chaofeng Jiang, Yihao Zhang, Yong Yang, Yi-Wen Yao, Huai Li, Fei Gan, Xiao-Feng Tang, B. Tang   +9 more
semanticscholar   +1 more source

The structure of DLP12 endolysin exhibiting alternate loop conformation and comparative analysis with other endolysins

Proteins: Structure, Function, and Bioinformatics, 2017
AbstractThe lytic enzyme, endolysin, is encoded by bacteriophages (phages) to destroy the peptidoglycan layer of host bacterial cells. The release of phage progenies to start the new infection cycle is dependent on the cell lysis event. Endolysin encoded by DLP12 cryptic prophage is a SAR endolysin which is retained by the bacterium presumably due to ...
Kesavan Babu, Arockiasamy Arulandu, Krishnaswamy Sankaran   +2 more
openaire   +2 more sources

Surface charge of the C-terminal helix is crucial for antibacterial activity of endolysin against Gram-negative bacteria

Journal of Biomedical Sciences
Endolysins are promising alternatives to antibiotics because they can lyse bacterial cells rapidly with a low risk of resistance development, however, their effectiveness against Gram-negative bacteria is hindered by the presence of the outer membrane ...
Joonbeom Kim, S. Son, Eunbyeol Ahn, Hae-Gun Park, Sangryeol Ryu   +4 more
semanticscholar   +1 more source

Activity of GS-linked chimeric endolysin CHAPk-SH3bk against methicillin-resistant Staphylococcus aureus biofilms: an in-vitro, ex-vivo and in-vivo study

npj Biofilms and Microbiomes
The evolution of antibiotic resistance and the propensity of methicillin-resistant Staphylococcus aureus to form biofilms impedes antibiotic therapy, which enkindles the rummage for novel therapeutic agents like bacteriophage endolysins.
Manisha Behera, Priyanka Singh, Anita Kamra Verma, Sachinandan De, S. M. Ghorai   +4 more
semanticscholar   +1 more source