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Bacteriophage endolysins — current state of research and applications
Current Opinion in Microbiology, 2005Endolysins are phage-encoded enzymes that break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. Their action is tightly regulated by holins, by membrane arrest, and by conversion from their inactive to active state. Recent research has not only revealed the unexpected diversity of these highly specific hydrolases but
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Endolysin from Giant Bacteriophage Disrupts B. anthracis
Microbe Magazine, 2014The endolysin enzyme from a giant but mostly temperate bacteriophage, recovered from a zebra carcass as well as a nearby soil sample in Etosha National Park in Namibia, Africa, is effective in disrupting Bacillus anthracis and other Bacillus species, according to Holly Ganz at the University of California, Davis, Jochen Klumpp of ETH Zurich in Zurich ...
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Novel endolysin (for gram negative pathogens)
2012The present invention relates to a polypeptide with endolysin activity comprising an amino acid sequence according to SEQ ID No. 1 and fragments or derivatives thereof, or fusion proteins derived thereof. Moreover, the present invention relates to nucleic acid molecules encoding said polypeptide or fusion protein, vectors comprising said nucleic acid ...
Azeredo, Joana +4 more
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Endolysins for food biopreservation
Trabajo presentado en el Bacteriophage Meeting, celebrado en China en noviembre de ...openaire +1 more source