Results 21 to 30 of about 208,461 (352)

Endometrial cancer with concomitant endometriosis is highly associated with ovarian endometrioid carcinoma: a retrospective cohort study

open access: yesBMC Women's Health, 2022
Background Endometriosis is assumed to be involved in ovarian cancer development, which is called endometriosis-associated ovarian cancer (EAOC). Uterine endometrial cells may be the cell of origin of EAOC. Accumulated carcinogenic changes in the uterine
Aya Ishizaka   +13 more
doaj   +1 more source

Unravelling the interplay between microbiome, inflammation, metabolic dysregulation and endometrial carcinogenesis [PDF]

open access: yes, 2022
Background Inflammatory and metabolic cues have long been associated with the pathogenesis of endometrial cancer. Increasing evidence implicates the reproductive tract microbiota with health and disease states, however its role in metabolic and ...
Semertzidou, Anysia
core   +1 more source

LncRNA SNHG4 Modulates EMT Signal and Antitumor Effects in Endometrial Cancer through Transcription Factor SP-1

open access: yesBiomedicines, 2023
Long non-coding RNAs (lncRNAs) are implicated in the initiation and progression of a variety of tumors, including endometrial cancer. However, the mechanisms of lncRNA in endometrial cancer formation and progression remain largely unknown. In this study,
Lee Kyung Kim   +5 more
doaj   +1 more source

Relationship between duration of breast feeding and endometrial cancer: a case-control study [PDF]

open access: yesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: Endometrial cancer is the most common gynecologic malignancy in developed countries. The incidence of endometrial cancer is increasing in Iran. The risk of endometrial cancer is related to estrogen levels that breastfeeding reduces it. This
Zohreh Yeganeh   +5 more
doaj   +1 more source

Computer-aided diagnosis in histopathological images of the endometrium using a convolutional neural network and attention mechanisms [PDF]

open access: yesIEEE Journal of Biomedical and Health Informatics, 2020, 26(6): 1664-1676, 2019
Uterine cancer, also known as endometrial cancer, can seriously affect the female reproductive organs, and histopathological image analysis is the gold standard for diagnosing endometrial cancer. However, due to the limited capability of modeling the complicated relationships between histopathological images and their interpretations, these computer ...
arxiv   +1 more source

Metapristone (RU486-derivative) inhibits endometrial cancer cell progress through regulating miR-492/Klf5/Nrf1 axis

open access: yesCancer Cell International, 2021
Background Endometrial cancer is an invasive gynecological cancer prevalent in the world. The pathogenesis of endometrial cancer is related to multiple levels of regulation, referring to oestrogen, tumor-suppressor gene (e.g. PTEN) or microRNAs (e.g. miR-
Yue Chang   +5 more
doaj   +1 more source

Unique Molecular Features in High-Risk Histology Endometrial Cancers [PDF]

open access: yes, 2019
Endometrial cancer is the most common gynecologic malignancy in the United States and the sixth most common cancer in women worldwide. Fortunately, most women who develop endometrial cancer have low-grade early-stage endometrioid carcinomas, and simple ...
Collins, Kaitlyn   +4 more
core   +1 more source

Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk:a Mendelian randomization analysis [PDF]

open access: yes, 2022
Endometrial cancer is the most common gynaecological cancer in high-income countries. Elevated body mass index (BMI) is an established modifiable risk factor for this condition and is estimated to confer a larger effect on endometrial cancer risk than ...
Davey Smith, George   +14 more
core   +3 more sources

Type II transmembrane serine proteases 4 (TMPRSS4) promotes proliferation, invasion and epithelial–mesenchymal transition in endometrial carcinoma cells (HEC1A and Ishikawa) via activation of MAPK and AKT

open access: yesAnimal Cells and Systems, 2021
Endometrial cancer is the most common gynecological cancer in the developed countries. Type II transmembrane serine proteases 4 (TMPRSS4) is a newly discovered transmembrane protein, which may be related to the invasion, metastasis of the tumor and the ...
Huan Xiao   +4 more
doaj   +1 more source

Mutations and amplification of oncogenes in endometrial cancer [PDF]

open access: yes, 1999
Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
An, Han-Xiang   +5 more
core   +1 more source

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