Results 21 to 30 of about 229,435 (354)

Mutations and amplification of oncogenes in endometrial cancer [PDF]

, 1999
Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
An, Han-Xiang, Beckmann, Matthias W., Bender, Hans G., Cho, Yong-Jig, Hantschmann, Peer, Niederacher, Dieter   +5 more
core   +1 more source

ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

Scientific Reports, 2021
In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but
Vei Mah, Yahya Elshimali, Alison Chu, Neda A. Moatamed, Jamar P. Uzzell, Jessica Tsui, Stephen Schettler, Hania Shakeri, Madhuri Wadehra   +8 more
doaj   +1 more source

Unique Molecular Features in High-Risk Histology Endometrial Cancers [PDF]

, 2019
Endometrial cancer is the most common gynecologic malignancy in the United States and the sixth most common cancer in women worldwide. Fortunately, most women who develop endometrial cancer have low-grade early-stage endometrioid carcinomas, and simple ...
Collins, Kaitlyn, Hawkins, Shannon M., Jones, Devin E., Pandita, Pooja, Wang, Xiyin   +4 more
core   +1 more source

Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]

, 2020
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal, Ayhan, Chiarelli, Di Palma, Fukunaga, Giampaolino, Heatley, Horita, Houghton, Jiang, Kuwashima, Lin, Longacre, Lu, Ma, Mazur, McAlpine, McCluggage, McCluggage, Moher, Nei, Nomura, Nomura, Němejcová, Ohishi, Ota, Raffone, Raffone, Raffone, Raffone, Raffone, Raffone, Ramos, Stelloo, Strickland, Takahashi, Talhouk, Terada, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Young, Zhang   +46 more
core   +1 more source

Prevalence of Co-existing Endometrial Carcinoma in Patients with Preoperative Diagnosis of Endometrial Hyperplasia [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Endometrial hyperplasia has been associated with the presence of concomitant endometrial carcinoma. In this study, patients who were diagnosed with endometrial hyperplasia and had hysterectomy, determination of the incidence of ...
Pinar Kadirogullari, Cemal Resat Atalay, Ozhan Ozdemir, Mustafa Erkan Sari   +3 more
doaj   +1 more source

Οutcomes for patients who are diagnosed with breast and endometrial cancer [PDF]

, 2013
The present study sought to determine the survival outcomes for women diagnosed with breast and endometrial cancer. Using SEER data, a population-based cohort study of women diagnosed with breast and endometrial cancer was conducted.
Margenthaler, Julie A, Martin-Dunlap, Tonya M, Wachtel, Mitchell S   +2 more
core   +2 more sources

Genetics of Endometrial Cancers [PDF]

Obstetrics and Gynecology International, 2010
Endometrial cancers exhibit a different mechanism of tumorigenesis and progression depending on histopathological and clinical types. The most frequently altered gene in estrogen‐dependent endometrioid endometrial carcinoma tumors is PTEN. Microsatellite instability is another important genetic event in this type of tumor. In contrast, p53 mutations or
Miki Morioka, Masaaki Nagatsuka, Tsuyoshi Okuda, Yuditiya Purwosunu, Yuditiya Purwosunu, Masaki Hayashi, Takashi Okai, Akihiko Sekizawa   +7 more
openaire   +3 more sources

Prognostic value of angiogenic markers of endometrial cancer (literature review)

Сибирский онкологический журнал, 2022
Endometrial cancer is the most common cancer of the female reproductive organs. The purpose of the study was to summarize the available data on the role of angiogenic markers in the development, progression and prognosis of endometrial cancer.
N. S. Zolotukhina, L. F. Gulyaeva
doaj   +1 more source

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk. [PDF]

, 2014
Common variants in the hepatocyte nuclear factor 1 homeobox B (HNF1B) gene are associated with the risk of Type II diabetes and multiple cancers. Evidence to date indicates that cancer risk may be mediated via genetic or epigenetic effects on HNF1B gene ...
Aida K. Dieffenbach, Alexander Hein, Alfons Meindl, Alison M. Dunning, Amanda B. Spurdle, Angel Carracedo, Angela Cox, Angela Jones, Anja Rudolph, Anjali K. Henders, Anne-Lise Børresen-Dale, Annika Lindblom, Anthony J. Swerdlow, Arif B. Ekici, Attila Teoman, Augusto Rojas-Martinez, Bach, Bahcall, Barbara Burwinkel, Berndt, Boris Winterhoff, Brooke L. Fridley, Buchanan, Buchner, Cancer Genome Atlas Research Network, Cancer Genome Atlas Research, N, Carina Walpole, Catherine S. Healey, Cerami, Cuff, Dale R. Nyholt, Deborah J. Thompson, Diether Lambrechts, Douglas F. Easton, Dunham, Edwards, Eeles, Eeles, Eger, Elizabeth Holliday, Ellen L. Goode, Emma Tham, Erika Santos, Felicity A. Lose, Fergus J. Couch, Ferreira, Fiona Bruinsma, Frederic Amant, Frederik Marme, Gao, Garcia-Closas, Garg, Gauderman, Geoffrey Otton, Gerasimos Tzortzatos, Glinsky, Graham G. Giles, Grant W. Montgomery, Grisanzio, Gudmundsson, Harries, Helga B. Salvesen, Henrica M.J. Werner, Hermann Brenner, Higgins, Hiltrud Brauch, Houlston, Howie, Howie, Hughes, Ian Tomlinson, Ingo Runnebaum, Janet E. Olson, Jenny Chang-Claude, Jeroen Depreeuw, Jianjun Liu, Jingmei Li, Jirong Long, Jodie N. Painter, Joe Dennis, John Attia, John L. Hopper, Jonathan P. Tyrer, Jone Trovik, Julian Peto, Julie M. Cunningham, Juliet D. French, Jyotsna Batra, Kaltin Ferguson, Kamila Czene, Katie Ashton, Kimberley Howarth, Kristine M. Hillman, Kyriaki Michailidou, Lazarevich, Leire Moya, Lieve Coenegrachts, Liu, Long, Luis Carvajal-Carmona, Lynn Martin, Ma. Magdalena Echeverry De Polanco, Macintyre, Maggie Gorman, Manjeet K. Bolla, Manuel R. Teixeira, Mark McEvoy, Matthias Dürst, Matthias Ruebner, Matthias W. Beckmann, Matthieu Moisse, McEvoy, McGregor, Melissa C. Southey, Michailidou, Miriam Mints, Mitul Shah, Monica Sans, Nicholas G. Martin, Nicholas Orr, Nicola Johnson, Painter, Pamela Pollock, Paul D.P. Pharoah, Penelope M. Webb, Per Hall, Peter A. Fasching, Peter Hillemanns, Pharoah, Pruim, Qin Wang, Rachel Palmieri Weber, Rodney J. Scott, Sakoda, Sean C. Dowdy, Sergi Castellvi-Bel, Shahana Ahmed, Shao, Shen, Shirley Hodgson, Singh, Spoelstra, Spurdle, Stacey L. Edwards, Stefan P. Renner, Stefanie Schrauwen, Sun, Susanne Kaufmann, Takata, Tavassoli, Teo, Terasawa, Thilo Dörk, Thomas, Timothy Cheng, Tony Proietto, Tormund S. Njolstad, Tracy A. O'Mara, Tsuchiya, Udler, Vessela N. Kristensen, Wei Zheng, Wellcome Trust Case Control Consortium, Xiao-Ou Shu, Yong-Bing Xiang, Zhihua Chen   +165 more
core   +7 more sources

Pathology findings among women with alterations in uterine bleeding patterns in cameroon

Gynecologic Oncology Reports, 2021
Purpose: Endometrial cancer is on the rise in high-income countries but it has not been adequately studied in low-and-middle income countries especially in sub-Saharan Africa (SSA), likely due to scarce pathology facilities. The purpose of this study was
Simon M. Manga, Yuanfan Ye, Jeff M. Szychowski, Kathleen L. Nulah, Calvin Ngalla, Kaitlyn Kincaid, Teresa K.L. Boitano, Alan T. Tita, Isabel Scarinci, Warner K. Huh, Zacharie Sando, Margaret I. Liang   +11 more
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