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Detecting endometrial cancer [PDF]
The Obstetrician & Gynaecologist, 2021 Key content Endometrial cancer (EC) is the most common gynaecological cancer in the UK. Ninety percent of women with EC present with postmenopausal bleeding (PMB), but less than 10% of women with PMB have a sinister underlying cause. National Institute for Health and Care Excellence guidance advises that symptomatic postmenopausal women undergo ...
Eleanor R Jones +3 more
openaire +2 more sources
Reproductive Factors and Endometrial Cancer Risk Among Women
JAMA Network Open, 2023 Key Points Question Are reproductive factors and endometrial cancer risk associated among individuals in East Asia? Findings In this pooled cohort study of 332 625 women including 1005 endometrial cancer cases from 13 Asian cohort studies, late menarche,
R. Katagiri +36 more
semanticscholar +1 more source
Immunotherapy in endometrial cancer
International Journal of Gynecological Cancer, 2023 The Cancer Genome Atlas (TCGA) endometrial cancer data expanded our knowledge about the role of different immunotherapeutic approaches based on molecular subtypes.
Haider Mahdi +2 more
semanticscholar +1 more source
The Lancet, 2005 Each year, endometrial cancer develops in about 142,000 women worldwide, and an estimated 42,000 women die from this cancer. The typical age-incidence curve for endometrial cancer shows that most cases are diagnosed after the menopause, with the highest incidence around the seventh decade of life. The appearance of symptoms early in the course explains
Amant, Frédéric +5 more
openaire +6 more sources
International Journal of Gynecological Cancer, 2022 Background The endometrial cancer molecular classification has been integrated into the 2020 World Health Organization (WHO) diagnostic classification and European treatment guidelines, and provides direction towards more effective and less toxic ...
Rainbo Research +2 more
semanticscholar +1 more source
Cancer, 2021 Endometrial cancers (ECs) with somatic mutations in DNA polymerase epsilon (POLE) are characterized by unfavorable pathological features, which prompt adjuvant treatment.
J. McAlpine +22 more
semanticscholar +1 more source
Endometrial hyperplasia as a risk factor of endometrial cancer
Archives of Gynecology and Obstetrics, 2022 Endometrial hyperplasia (EH) is the precursor lesion for endometrioid adenocarcinoma of the endometrium (EC), which represents the most common malignancy of the female reproductive tract in industrialized countries. The most important risk factor for the
Lisa K. Nees +6 more
semanticscholar +1 more source
Pre-eclampsia during pregnancy and risk of endometrial cancer: a systematic review and meta-analysis
BMC Women's Health, 2023 Background Pre-eclampsia may be associated with the development of endometrial cancer; however, previous findings have been conflicting. Objectives To investigate if pre-eclampsia is associated with an increased risk of endometrial cancer.
H Jordao +5 more
doaj +1 more source
Endometrial Cancer in Reproductive Age: Fertility-Sparing Approach and Reproductive Outcomes
Cancers, 2022 Simple Summary In this paper we addressed the challenges encountered by women diagnosed with endometrial cancers during their reproductive years. Depending on the genetic profile of the endometrial cancer, these young patients may benefit from fertility ...
L. Mutlu +5 more
semanticscholar +1 more source
Current and Emerging Prognostic Biomarkers in Endometrial Cancer
Frontiers in Oncology, 2022 Endometrial cancer is the most common gynaecological malignancy in high income countries and its incidence is rising. Whilst most women with endometrial cancer are diagnosed with highly curable disease and have good outcomes, a significant minority ...
K. Njoku, Chloe E. Barr, E. Crosbie
semanticscholar +1 more source