Results 21 to 30 of about 210,178 (195)

LncRNA SNHG4 Modulates EMT Signal and Antitumor Effects in Endometrial Cancer through Transcription Factor SP-1

Biomedicines, 2023
Long non-coding RNAs (lncRNAs) are implicated in the initiation and progression of a variety of tumors, including endometrial cancer. However, the mechanisms of lncRNA in endometrial cancer formation and progression remain largely unknown. In this study,
Lee Kyung Kim, Sun-Ae Park, Eun Ji Nam, Young Tae Kim, Tae-Hwe Heo, Hee Jung Kim   +5 more
doaj   +1 more source

Association between diabetes, diabetes treatment and risk of developing endometrial cancer. [PDF]

, 2014
BackgroundA growing body of evidence suggests that diabetes is a risk factor for endometrial cancer incidence. However, most of these studies used case-control study designs and did not adjust for obesity, an established risk factor for endometrial ...
Beresford, S, Chen, C, Chlebowski, R, Garcia, L, Kuller, L, Luo, J, Margolis, KL, Regier, M, Wactawski-Wende, J   +8 more
core   +2 more sources

Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]

, 2020
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna, Chen, Joseph C, Giudice, Linda C, Greenblatt, Ruth M, Houshdaran, Sahar, Irwin, Juan C, Smith-McCune, Karen, Vallvé-Juanico, Júlia, Vo, Kim Chi   +8 more
core   +2 more sources

Endometrial cancer with concomitant endometriosis is highly associated with ovarian endometrioid carcinoma: a retrospective cohort study

BMC Women's Health, 2022
Background Endometriosis is assumed to be involved in ovarian cancer development, which is called endometriosis-associated ovarian cancer (EAOC). Uterine endometrial cells may be the cell of origin of EAOC. Accumulated carcinogenic changes in the uterine
Aya Ishizaka, Ayumi Taguchi, Tetsushi Tsuruga, Marie Maruyama, Akira Kawata, Yuichiro Miyamoto, Michihiro Tanikawa, Masako Ikemura, Kenbun Sone, Mayuyo Mori, Kaori Koga, Tetsuo Ushiku, Katsutoshi Oda, Yutaka Osuga   +13 more
doaj   +1 more source

Mutations and amplification of oncogenes in endometrial cancer [PDF]

, 1999
Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
An, Han-Xiang, Beckmann, Matthias W., Bender, Hans G., Cho, Yong-Jig, Hantschmann, Peer, Niederacher, Dieter   +5 more
core   +1 more source

Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]

, 2020
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal, Ayhan, Chiarelli, Di Palma, Fukunaga, Giampaolino, Heatley, Horita, Houghton, Jiang, Kuwashima, Lin, Longacre, Lu, Ma, Mazur, McAlpine, McCluggage, McCluggage, Moher, Nei, Nomura, Nomura, Němejcová, Ohishi, Ota, Raffone, Raffone, Raffone, Raffone, Raffone, Raffone, Ramos, Stelloo, Strickland, Takahashi, Talhouk, Terada, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Young, Zhang   +46 more
core   +1 more source

ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

Scientific Reports, 2021
In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but
Vei Mah, Yahya Elshimali, Alison Chu, Neda A. Moatamed, Jamar P. Uzzell, Jessica Tsui, Stephen Schettler, Hania Shakeri, Madhuri Wadehra   +8 more
doaj   +1 more source

Endometrial cancer following endometrial resection [PDF]

Gynecological Surgery, 2007
Endometrial ablation has emerged as a viable alternative to hysterectomy in the treatment of medically intractable dysfunctional uterine bleeding. However, this procedure cannot guarantee complete removal of the entire endometrium. Cases of endometrial cancer after endometrial ablation have been reported in the literature.
Giorgia Gaia, Revaz Botchorishvili, Michel Canis, Benoit Rabischong, Kris Jardon, Juan Real Escalona, Guy Lesec, Frederic Penault-Llorca, Pierre Dechelotte, Jean Luc Pouly, Gérard Mage   +10 more
openaire   +1 more source

Relationship between duration of breast feeding and endometrial cancer: a case-control study [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: Endometrial cancer is the most common gynecologic malignancy in developed countries. The incidence of endometrial cancer is increasing in Iran. The risk of endometrial cancer is related to estrogen levels that breastfeeding reduces it. This
Zohreh Yeganeh, Zohreh Sheikhan, Parastoo Hajian, Taraneh Esteki, Malihe Nasiri, Nahid Khodakarami   +5 more
doaj   +1 more source

Οutcomes for patients who are diagnosed with breast and endometrial cancer [PDF]

, 2013
The present study sought to determine the survival outcomes for women diagnosed with breast and endometrial cancer. Using SEER data, a population-based cohort study of women diagnosed with breast and endometrial cancer was conducted.
Margenthaler, Julie A, Martin-Dunlap, Tonya M, Wachtel, Mitchell S   +2 more
core   +2 more sources