Molecular testing of soft tissue tumors
Abstract Background The diagnosis of soft tissue tumors is challenging, especially when the evaluable material procured is limited. As a result, diagnostic ancillary testing is frequently needed. Moreover, there is a trend in soft tissue pathology toward increasing use of molecular results for tumor classification and prognostication. Hence, diagnosing
Douglas Rottmann+2 more
wiley +1 more source
Correlation of Hypothyroidism and Endometrial Carcinoma
Objective To investigate the relationship between hypothyroidism and endometrial carcinoma, and to explore the relationship of the differentiation degree of endometrial carcinoma, the expression of estrogen receptor (ER) and progesterone receptor (PR) in
LIAO Yuping, YANG Bing
doaj +1 more source
Machine Learning Methods in the Computational Biology of Cancer [PDF]
The objectives of this "perspective" paper are to review some recent advances in sparse feature selection for regression and classification, as well as compressed sensing, and to discuss how these might be used to develop tools to advance personalized cancer therapy.
arxiv +1 more source
Association of endometrioid ovarian carcinoma arising from endometriosis, endometrioid endometrial carcinoma, and high-grade undifferentiated endometrial sarcoma. a case report [PDF]
Endometriosis is a chronic disease that affects women of reproductive age. Malignant transformation in endometriosis is considered to be an unusual event, only occurring in 0.7-0.1% of cases.
Caserta, D.+3 more
core +1 more source
Analysis of lncRNA sequences: FAM3D-AS1, LINC01230, LINC01315 and LINC01468 in endometrial cancer
Background The analysis of long non-coding RNA (lncRNA) in endometrial cancer is a novel field of science. Although numerous lncRNA sequences have been identified until today, their correlation with endometrial cancer is still undetermined.
Jan Bieńkiewicz+7 more
doaj +1 more source
A regression framework for a probabilistic measure of cost-effectiveness [PDF]
To make informed health policy decisions regarding a treatment, we must consider both its cost and its clinical effectiveness. In past work, we introduced the net benefit separation (NBS) as a novel measure of cost-effectiveness. The NBS is a probabilistic measure that characterizes the extent to which a treated patient will be more likely to ...
arxiv
Evaluation of apparent diffusion coefficient in endometrial carcinoma compared to normal endometrium: a retrospective study [PDF]
Background: To determine whether diffusion-weighted imaging (DWI) with measurement of apparent diffusion coefficient (ADC) will help in differentiating endometrial cancer from normal endometrium and to determine whether the grades of endometrial cancer ...
Anand, Rajeev+2 more
core +2 more sources
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause+2 more
wiley +1 more source
Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma
Objective:The aim of the study was to compare mean platelet volume (MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), eosinophil-lymphocyte ratio (ELR), platelet/lymphocyte ratio (PLR) between ...
Serkan Kumbasar+6 more
doaj +1 more source
The effects of androgen therapy on the endometrium of transgender men [PDF]
Individuals who identify themselves as transgender have gender identities that do not match their anatomical sex. Females who identify as male, also known as female-to-male transgender (FTM), may opt to undergo hormonal and surgical treatment in order to
Shah, Anita
core