Results 71 to 80 of about 4,742,503 (345)

Ninjurin 2 rs118050317 gene polymorphism and endometrial cancer risk

Cancer Cell International, 2020
Endometrial cancer is one of the most common female reproductive system tumors. Ninjurin2 (NINJ2) is a new adhesion factor. As a vascular susceptibility gene, it is highly expressed in other cancers and promotes the growth of cancer cells.
Yimin Cheng, Liting Yang, Guangyao Shi, Peng Chen, Liang Li, Hangrong Fang, Chao Chen   +6 more
semanticscholar   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

Diagnostic accuracy of sonohysterography vs hysteroscopy in benign uterine endocavitary findings [PDF]

, 2015
OBJECTIVE: To compare diagnostic accuracy of sonohysterography vs hysteroscopy in patients with benign uterine endocavitary findings. PATIENTS AND METHODS: This retrospective study evaluated 202 patients submitted to sonohysterography after transvaginal ...
Bianchi, Paola, Caserta, Donatella, Catalano, Angelica, Cozza, Giuliana, DI PROPERZIO, Matilde, Frega, Antonio, Gentile, M, Manzara, F, Marziani, Rosalia, Milazzo, Gn, Schimberni, Mauro, Torcia, Francesco, Zinna, M   +12 more
core  

Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]

, 2009
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Hembree JR, Huynh H, Munetoshi Kanayama, Ohtsuki T, Ohtsuki T, Pierro E, Sakae Takeuchi, Shiraga M, Sumio Takahashi, Takaoka M, Tetsuya Maekawa   +10 more
core   +1 more source

CircRNA WHSC1 targets the miR‐646/NPM1 pathway to promote the development of endometrial cancer

Journal of Cellular and Molecular Medicine, 2020
Circular RNAs (circRNAs) play important roles in human cancer progression. Their high stability and tissue specificity make circRNAs important molecular targets for clinical diagnosis, treatment and prognosis.
Yao Liu, Shuo Chen, Z. Zong, X. Guan, Yang Zhao   +4 more
semanticscholar   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Glucocorticoid receptor expression in 20 solid tumor types using immunohistochemistry assay. [PDF]

, 2017
BackgroundGlucocorticoid receptor (GR) activity plays a role in many aspects of human physiology and may play a crucial role in chemotherapy resistance in a wide variety of solid tumors.
Block, Thaddeus S, Lynch, Frank J, Munster, Pamela N, Murphy, Tiffany I, Nguyen, Dat P   +4 more
core   +2 more sources

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Advanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley   +7 more
wiley   +1 more source

Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer

International Journal of Cancer, 2020
Blood lipids have been associated with the development of a range of cancers, including breast, lung and colorectal cancer. For endometrial cancer, observational studies have reported inconsistent associations between blood lipids and cancer risk.
P. Kho, F. Amant, D. Annibali, K. Ashton, J. Attia, P. Auer, M. Beckmann, A. Black, L. Brinton, D. Buchanan, S. Chanock, Chu Chen, Maxine M Chen, Timothy H. T. Cheng, L. Cook, Marta Crous-Bous, K. Czene, I. De Vivo, J. Dennis, T. Dörk, S. Dowdy, A. Dunning, M. Dürst, D. Easton, A. Ekici, P. Fasching, B. Fridley, C. Friedenreich, M. García-Closas, M. Gaudet, G. Giles, E. Goode, Maggie Gorman, C. Haiman, P. Hall, S. Hankinson, A. Hein, P. Hillemanns, S. Hodgson, E. Hoivik, E. Holliday, D. Hunter, Angela Jones, P. Kraft, C. Krakstad, D. Lambrechts, L. Le Marchand, Xiaolin Liang, A. Lindblom, J. Lissowska, J. Long, Lingeng Lu, A. Magliocco, Lynn Martin, M. McEvoy, R. Milne, M. Mints, R. Nassir, G. Otton, C. Palles, Loreall Pooler, Tony Proietto, T. Rebbeck, S. Renner, H. Risch, M. Rübner, I. Runnebaum, C. Sacerdote, G. Sarto, F. Schumacher, R. Scott, V. Setiawan, M. Shah, Xin Sheng, X. Shu, M. Southey, E. Tham, I. Tomlinson, J. Trovik, Constance Turman, J. Tyrer, D. J. Van Den Berg, Zhaoming Wang, N. Wentzensen, Lucy Xia, Y. Xiang, Hannah P. Yang, Herbert Yu, W. Zheng, P. Webb, Deborah J. Thompson, A. Spurdle, Dylan M Glubb, T. O’Mara   +93 more
semanticscholar   +1 more source

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

Advanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source