Results 11 to 20 of about 127,260 (361)

Study of ER, PR and VEGF Expression in Endometrial Epithelial Neoplasms and its Association with Histological Stage and Grade of Endometrial Carcinoma [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Introduction: Exogenous or endogenous oestrogen induces hyperplastic endometrium which presents with abnormal uterine bleeding. Atypical endometrial hyperplasia is the precursor for endometrial carcinoma. In case of invasive carcinoma, oestrogen Receptor
SK Samim Rahaman   +3 more
doaj   +1 more source

lncRNA-ZFAS1 promotes the progression of endometrial carcinoma by targeting miR-34b to regulate VEGFA expression

open access: yesOpen Medicine, 2021
Zinc finger nuclear transcription factor, X-box binding 1-type containing 1 antisense RNA 1 (ZFAS1) functions as an oncogenic long noncoding RNA (lncRNA) to promote proliferation and metastasis of endometrial carcinoma cell; however, the underlying ...
Zhu Hongli, Cheng Qihui, Cai Hong
doaj   +1 more source

Livin/BIRC7 gene expression as a possible diagnostic biomarker for endometrial hyperplasia and carcinoma

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family which are implicated in development of cancer through the inhibition of apoptosis process.
Basma K. Elmekkawy   +4 more
doaj   +1 more source

A first-in-class POLRMT specific inhibitor IMT1 suppresses endometrial carcinoma cell growth

open access: yesCell Death and Disease, 2023
Exploring novel molecularly-targeted therapies for endometrial carcinoma is important. The current study explored the potential anti-endometrial carcinoma activity by a first-in-class POLRMT (RNA polymerase mitochondrial) inhibitor IMT1.
Shu-ping Li   +4 more
doaj   +1 more source

The Expression and Clinical Significance of Sphingosine Kinase 1 and Vascular Endothelial Growth Factor in Endometrial Carcinoma

open access: yesEmergency Medicine International, 2022
The aim of the study is to investigate the expression of sphingosine kinase 1 (SPHK1) and vascular endothelial growth factor (VEGF) in patients with endometrial carcinoma and its clinical significance. The tissues of 86 cases of patients with endometrial
Hong Yu   +6 more
doaj   +1 more source

A Potential Invasion-Promoting Role for Ezrin in Endometrial Carcinoma [PDF]

open access: yesResearch in Oncology, 2020
Background:Ezrin is a cell membrane-cytoskeleton linker that is essential to maintain the normal cell shape and the integrity of cell-cell adhesion. Overexpression of ezrin is correlated with poor prognosis in several malignancies.
Ahmed R. H. Ahmed   +3 more
doaj   +1 more source

Endometrial blood vessel morphometry in patients presenting with abnormal uterine bleeding

open access: yesIndian Journal of Pathology and Microbiology, 2022
Background: Abnormal uterine bleeding (AUB) is one of the most common problems encountered in gynecological practice. Various benign and malignant disorders of the endometrial tissue show vascular changes such as congestion, dilatation, and vessel wall ...
Neha M Bhosale   +3 more
doaj   +1 more source

Immunohistochemical study of Ki-67 in Hyperplastic and Endometrium Carcinoma: A Comparative Study [PDF]

open access: yesArchives of Razi Institute, 2022
Endometrial hyperplasia is defined as a common clinical disorder caused by the increased levels of estrogens with low levels of progesterone; therefore, this hormonal imbalance leads to an increase in the proliferation rate of the endometrial cells ...
R Ghalib Farhood, I Abd Ali Al-Humairi
doaj   +1 more source

Programmed death ligand 1 expression levels, clinicopathologic features, and survival in surgically resected sarcomatoid lung carcinoma [PDF]

open access: yesAsia Pac J Clin Oncol 2020 1 9, 2020
Aim: To determine the programmed death ligand-1 (PD-L1) expression rates in sarcomatoid lung carcinomas and to compare clinicopathologic features and survival rates of PD-L1-positive and negative patients. Methods: PD-L1 expression was evaluated in 65 surgically resected sarcomatoid carcinomas.
arxiv   +1 more source

Risk of atypical hyperplasia and endometrial carcinoma after initial diagnosis of non-atypical endometrial hyperplasia: A long-term follow-up study

open access: yesPLoS ONE, 2022
Objectives The strong association between atypical endometrial hyperplasia and endometrial carcinoma is well established, but data on the risk of atypical hyperplasia and carcinoma in Danish women with non-atypical endometrial hyperplasia are almost non ...
Clara M. Prip   +4 more
doaj   +3 more sources

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