Results 101 to 110 of about 340,092 (249)
Expression of Cyclin D1 in Hyperplastic and Neoplastic Endometrial Lesions
Objective: To observe and evaluate the expression of Cyclin D1 in hyperplastic and neoplastic endometrial lesions. Methodology: This .retrospective analytical study was conducted at BMSI, JPMC over a five year period i.e.
Summayya Shawana +2 more
doaj
p21-Activated Kinases 1, 2 and 4 in Endometrial Cancers: Effects on Clinical Outcomes and Cell Proliferation [PDF]
p21-activated kinases (Paks) are serine/threonine protein kinases involved in biological events linked to malignant tumor progression. In this study, expression of Pak1, p-Pak2 Ser20, Pak4, pPak4 Ser474 in 21 normal endometrium, 16 hyperplastic ...
Chan, HY +9 more
core +1 more source
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani +3 more
wiley +1 more source
ENDOMETRIUM AND HORMONAL REPLACEMENT THERAPY
BACKGROUND Estrogen induces endometrial stimulation and increases the risk for endometrial hyperplasia and endometrial cancer. Added progestin diminishes endometrial stimulation.The risk for endometrial hyperplasia with hormonal replacement therapy (HRT)
Branka Žegura
doaj
Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li +13 more
wiley +1 more source
Cysteine-10 on 17 β-Hydroxysteroid dehydrogenase 1 has stabilizing interactions in the cofactor binding region and renders sensitivity to sulfhydryl modifying chemicals [PDF]
17 β-Hydroxysteroid dehydrogenase type 1 (17 β -HSD1) catalyzes the conversion of estrone to the potent estrogen estradiol. 17 β -HSD1 is highly expressed in breast and ovary tissues and represents a prognostic marker for the tumor progression and ...
Atanasov, Atanas G. +3 more
core +3 more sources
The role of biomarkers in endometrial cancer and hyperplasia: a literature review
Introduction: Endometrial cancer is the most common gynaecological cancer and its incidence is rising due to increasing obesity rates. We are also seeing an increasing trend of young women diagnosed with either endometrial cancer or its precancerous ...
Suzanna Hutt +5 more
semanticscholar +1 more source
ABSTRACT Background Atypical glandular cells (AGC) in cervical cytology, as defined by the Bethesda System, indicate nuclear atypia beyond reactive changes but without definitive features of malignancy. Although clinically significant because it prompts follow‐up procedures, no quantitative threshold exists for AGC diagnosis.
Havva Gokce Terzioglu +2 more
wiley +1 more source
Association of Endometrial Hyperplasia with Some Risk Factors
BACKGROUND AND OBJECTIVE: Endometrial cancer is one of the most common invasive gynecologic malignancies. Abnormal uterine bleeding (AUB) is the most common symptom in endometrial hyperplasia. Women with AUB are examined with dilation and curettage (D;C)
R Faraji,, N Esmailpour, B Behfar
doaj
Hypoxic damage and neovascularization of endometrium in endometrial hyperplasia [PDF]
E.A. Kazachkova, E.L. Kazachkov, A.V. Zatvornitskaya, E.E. Voropaeva South Ural State Medical University, Chelyabinsk, Russian Federation Aim: to assess the effects of hypoxic damage and neovascularization of endometrium in ...
E.A. Kazachkova +3 more
doaj

