Results 51 to 60 of about 38,327 (229)

Exosome‐Based Theranostic for Gastrointestinal Cancer: Advances in Biomarker Discovery and Therapeutic Engineering

Small Methods, EarlyView.
This review explores the dual roles of exosomes in gastrointestinal (GI) cancers as diagnostic biomarkers and therapeutic agents. It highlights advancements in exosomal miRNAs, lncRNAs, circRNAs, and proteins for cancer detection and prognosis. The study also examines engineering strategies for exosome‐based drug delivery systems, their potential to ...
Mohit J. Mehta, Dongjun Shin, Hyun Sung Park, Jun Su An, Seong Il Lim, Hyun Jin Kim, Seungpyo Hong, Jiyoon Bu   +7 more
wiley   +1 more source

Study of endometrium by trans-vaginal sonography and it’s correlation with histopathology in perimenopausal women with abnormal uterine bleeding [PDF]

, 2021
Background: Objectives of the study were to study the endometrial patterns in cases of abnormal uterine bleeding (AUB) and anatomical (structural) lesions of uterus using transvaginal sonography (TVS) and endometrial histopathology and to determine the ...
Chaturvedi, Shuchi, Saravade, Vandana R.
core   +2 more sources

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Co‐existing monophasic teratoma and uterine adenocarcinoma in a female dog [PDF]

, 2019
Ovarian teratomas are occasionally reported in dogs; the rarest type is the monophasic teratoma,composed of tissues originating from only one germ layer. Canine endometrial adenocarcinomas are also rare in dogs and mainly affect geriatric females.
Catarino, J.C, Faim, S., Freire, A., Neves, T., Orge, L., Payan-Carreira, R., Pires, M.A., Seixas, F., Vilhena, H.   +8 more
core   +2 more sources

Histological and immunohistochemical evaluation of leiomyoma and endometrial tissue in patients with uterine leiomyoma and endometrial hyperplasia [PDF]

Морфологія, 2014
Background. Uterine leiomyoma and endometrial hyperplasia are commonly found disorders because of quite similar pathogenic pathways associated with action of sex steroids such as estradiol and progesterone.
Potapov V.A., Donskaya Yu.V., Medvedev M.V.   +2 more
doaj  

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

Scientific Reports, 2021
In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but
Vei Mah, Yahya Elshimali, Alison Chu, Neda A. Moatamed, Jamar P. Uzzell, Jessica Tsui, Stephen Schettler, Hania Shakeri, Madhuri Wadehra   +8 more
doaj   +1 more source

Deep Phenotyping of Pathology‐Confirmed Benign Lesions in PTEN Hamartoma Tumor Syndrome Patients

Clinical Genetics, EarlyView.
Gastrointestinal, skin, thyroid, and vascular lesions are frequently present in PTEN Hamartoma Tumor Syndrome patients with little to no difference between sexes or by index status. Early‐onset lipomas (< 20 years) may be useful for early recognition of patients, and uterine polyps should be considered for inclusion as a PHTS‐related lesion.
Ane J. Schei‐Andersen, Janneke H. M. Schuurs‐Hoeijmakers, Rachel van der Post, Arjen R. Mensenkamp, Jolanda Schieving, PTEN Study Group, Muriel A. Adank, Mirjam de Jong, Marjolijn C.J. Jongemans, Liselotte P. van Hest, Yvette van Ierland, Edward M. Leter, Maartje Nielsen, Janet R. Vos, Nicoline Hoogerbrugge   +14 more
wiley   +1 more source

The Diagnostic Accuracy of Endometrial Sampling in Endometrial Hyperplasia

Gynecology Obstetrics & Reproductive Medicine, 2017
Objective: Endometrial hyperplasia is a premalignant lesion characterized with hyperplastic changes in endometrial gland and stromal structures. Its incidence is not exactly known. This study evaluated the accuracy of endometrial sampling of the patients
Serdar Başaranoğlu, Elif Ağaçayak, Şafak Hatırnaz, Ayşegül Deregözü, Mustafa Acet, Ebru Yüce, Talip Karaçor, Mehmet Sait İçen, Mehmet Sıddık Evsen, Talip Gül   +9 more
doaj   +1 more source

Evaluation of Diagnostic Accuracy of Directly Sampled Endometrial Cytology Using ThinPrep for Endometrial Malignancies: Comparison With Existing Endometrial Liquid‐Based Cytology

Cytopathology, EarlyView.
This study evaluated the diagnostic accuracy of directly sampled endometrial cytology using ThinPrep with a novel preparation method for detecting endometrial malignancies. The method yielded high‐quality cytology samples, and examiners with minimal experience demonstrated high diagnostic accuracy using the Yokohama System, supporting its global ...
Rie Ikemoto, Ken Tanikawa, Morio Ijichi, Miyoko Miyakawa, Kenji Yanoh, Jun Watanabe, Yutaka Nakamura, Ken Maruyama, Tadao K. Kobayashi, Hideaki Hirai, Noriyuki Furuta, Yasuo Hirai   +11 more
wiley   +1 more source