Results 91 to 100 of about 35,905 (266)

Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]

, 2018
Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng, Kommagani, Ramakrishna, Michalski, Stephanie   +2 more
core   +2 more sources

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

A Benign Ovarian Tumour developing an Endometrial Cancer? Sertoliform Ovarian Cystoadenoma getting together with an Endometrioid Adenocarcinoma [PDF]

, 2015
Medicin
Bueno Crespo, Andrés, Garcia Laencina, P.J., Garcia Nicolás, A.B., Isaac Montero, Alejandra, Martinez Más, José, Martínez Cendán, Juan Pedro, Remezal Solano, Manuel   +6 more
core   +2 more sources

63eP Exploring endometrial stromal tumors: Diagnostic dilemmas and treatment paradigm

ESMO Open
N. Singh, Z. Chowdhury, I. Dhal, S. Patne, B. Sansar, R. Jethani   +5 more
openaire   +3 more sources

Mechanistic Insights Into Recurrent Implantation Failure: The Lactate–H3K18la–SLC7A11 Axis Explored via Endometrial Organoid and Blastoid–Endometrial Cell Implantation Models

Cell Proliferation, EarlyView.
Clinical samples first revealed impaired lactate synthesis in RIF patients. Subsequently, using endometrial organoids and a blastoid‐endometrial cell implantation model, we demonstrated that lactate enhances endometrial receptivity via H3K18la‐mediated SLC7A11 activation.
Lingling Dong, Xiaobin Sun, Shiyu An, Jinfeng Xiang, Lingmin Hu, Dan Yao, Jiaqian Chang, Ruizhe Jia, Yang Yang, Shuxian Wang   +9 more
wiley   +1 more source

Uterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression. [PDF]

, 2012
Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive.
Burghard F. Klapp, Elke Winterhager, Gabriela Barrientos, Irene Tirado González, Nancy Freitag, Petra Moschansky, Petra von Kwiatkowski, Sandra M. Blois, Stefan Bauersachs, Teresa Otto, Victor L. J. L. Thijssen, Yan-Ling Wang   +11 more
core   +7 more sources

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Endometrial stromal sarcoma: Retrospective analysis of a tertiary care experience from India

Cancer Research, Statistics, and Treatment, 2020
Background: Endometrial stromal tumors are rare tumors of mesenchymal origin, conventionally classified as low-grade and high-grade tumors based on the mitotic count.
Rajit Rattan, Pragyat Thakur, Ankita Gupta, Raviteja Miriyala, Nagarjun Ballari, Bhavana Rai   +5 more
doaj   +1 more source

Endometrial stromal sarcoma - a rare tumor invading the heart [PDF]

Kardiovask Med, 2007
A 47-year-old female patient presented with progressive dyspnea on exertion, abdominal pain, loss of weight and tachycardia. The diagnosis of a retroperitoneal tumor with invasion of the vena cava inferior up to the right atrium was established by computed tomography.
openaire   +1 more source

Supplementary Figure 8 from Omental Adipose Tissue–Derived Stromal Cells Promote Vascularization and Growth of Endometrial Tumors [PDF]

, 2023
Ann H. Klopp, Yan Zhang, Travis Solley, Felipe Amaya‐Manzanares, Frank C. Marini, Michael Andreeff, Bisrat G. Debeb, Wendy A. Woodward, Rosemarie Schmandt, Russell R. Broaddus, Karen H. Lu, Mikhail G. Kolonin   +11 more
openalex   +1 more source