Effects of Testicular Platelet-Rich Plasma (PRP) Injection on Sperm Parameters in Men with Severe Oligoasthenoteratozoospermia (OAT): A Clinical Evaluation [PDF]
Background: Severe oligoasthenoteratozoospermia (OAT), characterized by a reduced sperm count, motility, andaltered morphology, presents a significant challenge in the field of male infertility.
Faezeh Fazli+5 more
doaj +1 more source
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang+13 more
wiley +1 more source
HPV infection and endometrial polyps: insights from a case-control study
Background Endometrial polyps are common benign lesions characterized by localized overgrowths of endometrial tissue within the uterine cavity. The etiology and pathogenesis of these polyps remain unclear.
Leila Nazari+6 more
doaj +1 more source
M1 M2 Macrophage Expression in Menstrual Blood Flakes of Women with Endometriosis [PDF]
Objectives: to measure and prove the increase of panmacrophage, macrophages M1 and M2 expression and decrease of ratio of M1/M2 in menstrual blood flakes of women with endometriosis.
Haslinda, Y. (Yulisa)+2 more
core
Endometriosis is a complex condition to treat because of uncertainties regarding its aetiology, the variety of its clinical presentation, the absence of a non-invasive diagnostic marker, its impact on quality of life and productivity, and the limited number of treatment options available.
Kennedy, S, Koninckx, P
openaire +3 more sources
Endometriosis in Adolescence [PDF]
Endometriosis is a common cause of pelvic pain and infertility. The majority of women report symptoms since adolescence, and there are rare cases of endometriosis in premenarchal age patients. Symptoms in adolescence are similar to those in adulthood. Treatment usually consists of oral contraceptives and nonsteroidal anti-inflammatory drugs.
Dessole M+2 more
openaire +4 more sources
Drug Screening of Primary Human Endometriotic Cells Based on Micro‐Encapsulating Microfluidic Chip
To address the challenges of unclear mechanisms and poor therapeutic efficacy in endometriosis (EMs), this study develops a microfluidic chip platform integrated with primary cell‐laden microcapsules. Gradient drug screening reveals individualized treatment response variations among patients and their correlation with clinical outcomes.
Qiong Chen+5 more
wiley +1 more source
Smooth muscle relaxant activity of Crocus sativus (saffron) and its constituents: possible mechanisms [PDF]
We praise the article by Mokhtari-Zaer et al. (2015) published in the Avicenna Journal of Phytomedicine on the effects of saffron on smooth muscle activity (Mokhtari-Zaer et al., 2015).
Mansoureh Gorginzadeh, Mansoureh Vahdat
doaj +1 more source
Effect of a period of swimming exercise and vitamin E intake on catalase and superoxide dismutase activity, and malondialdehyde levels in ovarian tissue of endometriosis model rats [PDF]
Introduction: Endometriosis is an estrogen-dependent inflammatory disease. Studies show that in women with endometriosis, the activity of macrophages in the peritoneal cavity increases, resulting in inflammatory reactions and stabilization of ...
Fatemeh Shahidian Akbar+2 more
doaj +1 more source
Feasibility of transabdominal electrohysterography for analysis of uterine activity in nonpregnant women [PDF]
Purpose: Uterine activity plays a key role in reproduction, and altered patterns of uterine contractility have been associated with important physiopathological conditions, such as subfertility, dysmenorrhea, and endometriosis.
Kuijsters, Nienke Pertronella Maria+4 more
core +2 more sources