Results 211 to 220 of about 145,931 (267)
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Angewandte Chemie International Edition in English, 1978
AbstractRestriction endonucleases are enzymes commonly found in bacteria which can fragment DNA. Cleavage of the DNA molecule takes place after recognition of a nucleotide sequence which is specific for each restriction endonuclease. Some of the enzymes split the DNA within the recognition sequence. This property allows these enzymes to be used for the
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AbstractRestriction endonucleases are enzymes commonly found in bacteria which can fragment DNA. Cleavage of the DNA molecule takes place after recognition of a nucleotide sequence which is specific for each restriction endonuclease. Some of the enzymes split the DNA within the recognition sequence. This property allows these enzymes to be used for the
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Biochimica et biophysica acta-Molecular basis of disease, 2014
Mouse transgenesis has been instrumental in determining the function of genes in the pathophysiology of human diseases and modification of genes by homologous recombination in mouse embryonic stem cells remains a widely used technology. However, this approach harbors a number of disadvantages, as it is time-consuming and quite laborious.
Wijshake, Tobias +2 more
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Mouse transgenesis has been instrumental in determining the function of genes in the pathophysiology of human diseases and modification of genes by homologous recombination in mouse embryonic stem cells remains a widely used technology. However, this approach harbors a number of disadvantages, as it is time-consuming and quite laborious.
Wijshake, Tobias +2 more
openaire +1 more source
PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease
Cell, 2016Pu Gao, Dinshaw J Patel
exaly
Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae
Nature, 1992Jeremy Thorner
exaly