Results 121 to 130 of about 64,056 (293)
Restriction endonucleases for pulsed field mapping of bacterial genomes
, 1987 Fundamental to many bacterial genome mapping strategies currently under development is the need to cleave the genome into a few large DNA fragments that can be resolved by pulsed field gel electrophoresis.
Robert Jones +3 more
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Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics
Interdisciplinary Medicine, EarlyView.This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li +7 more
wiley +1 more source
PROTEOMICS, EarlyView.ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt +11 more
wiley +1 more source
Gene turnover in the common ancestor of all C4 grasses
PLANTS, PEOPLE, PLANET, EarlyView.Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira +6 more
wiley +1 more source
Gene targeting in Silkworm (Bombyx mori) by Engineered Endonucleases
, 2013 This thesis describes the establishment of a precise gene targeting methodology in the silkworm Bombyx mori by technologies based on engineered endonucleases.
SAJWAN, Suresh Chandra Singh
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, 2014 +: restriction endonucleases used to cleave the PCR products.
Chun-Li Chai (515230) +9 more
core +1 more source
From wild to tamed: Reimagining novel crops through omics and local plant diversity
PLANTS, PEOPLE, PLANET, EarlyView.The global food system faces growing pressure from climate change, biodiversity loss, and rising nutritional demands. Agriculture has increased yields but reduced crop diversity, flavor, and nutritional quality, leaving societies vulnerable and dependent on a narrow set of staple species.
Alexandra Sanfeliu Meliá +1 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The tRNA splicing endonuclease (TSEN) removes introns from precursor tRNAs (pre‐tRNAs) in eukaryotes and archaea, but the architecture and subunit organization of plant TSEN remain poorly defined. Here, we integrated in planta bimolecular fluorescence complementation (BiFC) assays with AlphaFold3 (AF3)‐based structural modeling, molecular ...
Mohammad Moniruzzaman +2 more
wiley +1 more source
Improving adenine base editing precision by enlarging the recognition domain of CRISPR-Cas9
Nature CommunicationsDomain expansion contributes to diversification of RNA-guided-endonucleases including Cas9. However, it remains unclear how REC domain expansion could benefit Cas9.
Shuliang Gao +8 more
doaj +1 more source