Results 161 to 170 of about 55,351 (242)

Defense Systems and Prophage Detection in Streptococcus mutans Strains

Molecular Oral Microbiology, Volume 41, Issue 2, Page 57-68, April 2026.
ABSTRACT Although the species is extensively studied, limited data are available on antiphage defense systems (APDSs) in Streptococcus mutans. The present study aimed to explore the diversity and the occurrence of APDSs and to search for prophages in the genomes of clinical isolates of S. mutans using bioinformatics tools.
Olivier Claisse, Cas Mosterd, Claire Le Marrec, Johan Samot   +3 more
wiley   +1 more source

Aberrant RNA identification reveals triggers of transgene silencing. [PDF]

Plant Cell
Willoughby AC.
europepmc   +1 more source

Efficient Transgene‐Free Multiplexed Germline Editing via Viral Delivery of an Engineered TnpB

Plant Biotechnology Journal, EarlyView.
Trevor Weiss, Maris Kamalu, Honglue Shi, Gabriel Wirnowski, Alice Ingelsson, Jasmine Amerasekera, Kamakshi Vohra, Marena I. Trinidad, Zheng Li, Emily Freitas, Noah Steinmetz, Charlie Ambrose, Kerry Chen, Jennifer A. Doudna, Steven E. Jacobsen   +14 more
wiley   +1 more source

AcrVA3 Is a Double Strand DNA‐Cleaving Anti‐CRISPR That Indirectly Inhibits Cas12

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
This study reports the high‐resolution structure of the anti‐CRISPR protein AcrVA3 and reveals its unexpected inhibitory mechanism against Cas12. AcrVA3 does not directly interact with Cas12 but instead exhibits double‐stranded DNA cleavage activity.
Ju Hee Han, Young Jun Kang, So Yeon Lee, Hyo Been Jin, Chang Sup Lee, Hyun Ho Park   +5 more
wiley   +1 more source

Enzyme- and DNAzyme-Driven Transient Assembly of DNA-Based Phase-Separated Coacervate Microdroplets. [PDF]

J Am Chem Soc
Qin Y, Sohn YS, Nechushtai R, Xia F, Huang F, Willner I.   +5 more
europepmc   +1 more source

Glycosomal Phosphoenolpyruvate Carboxykinase CRISPR/Cas9‐Deletion and Its Role in Trypanosoma cruzi Metacyclogenesis and Infectivity in Mammalian Host

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Effects of PEPCK deficiency in Trypanosoma cruzi bioenergetics and life stages. ABSTRACT Trypanosoma cruzi, the causative agent of Chagas disease, possesses glycosomes—unique organelles that house key metabolic enzymes, several of which are promising therapeutic targets.
Carolina S. D. Vieira, Wei Wang, Fernando Sanchez‐Valdez, Jihyun Lim, Brooke E. White, Camilla G. S. Souza, Rick L. Tarleton, Marcia C. Paes, Natalia P. A. Nogueira   +8 more
wiley   +1 more source

Phage-encoded homing endonucleases attenuate bacterial immunity

Mahata T, Kanarek K, Ragavan RM, Haldar A, Shur G, Yehia R, Burstein D, Haitin Y, Qimron U, Salomon D.   +9 more
europepmc   +1 more source

Device-Free Nucleic Acid Detection Enabled by Body Temperature-Assisted DEMBA. [PDF]

ACS Omega
Yi J, Wan L, Ding J, Ye Q, Mu H, Yang G, Lu L, Zhou C.   +7 more
europepmc   +1 more source

A Modified Methyl Transferase Cofactor to Selectively Silence Gene Expression in Escherichia coli

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
Graphical abstract and table of contents entry A modified methyl transferase cofactor, containing AdoHcy azide, creates a specific single‐site molecular switch near a promoter, on plasmid DNA, preventing the expression of a single gene at the designated site, not observed with other modifications.
Oliver J. Irving, Samuel Stone, Robert K. Neely, Tim Albrecht   +3 more
wiley   +1 more source

Draft genome sequence of the <i>Alicyclobacillus acidocaldarius</i> strain LH1, isolated from a highly acidic solfatara field. [PDF]

Microbiol Resour Announc
Fuentes-Tobar FJ, Torres-Ponce N, Blamey JM, Cuadros-Orellana S.   +3 more
europepmc   +1 more source