Results 201 to 210 of about 155,310 (382)

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

Cancer Science, EarlyView.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki, Keiko Shinjo, Tatsunori Nishimura, Yutaka Kondo   +3 more
wiley   +1 more source

Regulation of Apoptotic Endonucleases by EndoG

DNA and Cell Biology, 2015
D. Zhdanov, T. Fahmi, Xiaoying Wang, E. Apostolov, N. Sokolov, S. Javadov, A. Basnakian   +6 more
semanticscholar   +1 more source

Unusual Disease‐Progression in Two Siblings With Xeroderma Pigmentosum Group G

Clinical Genetics, EarlyView.
Protein truncation mutations in the gene for XPG nuclease cause a very severe clinical phenotype. Two siblings have splicing mutations, which result in in‐frame deletions and a less severe phenotype.
Elena Botta, Heather Fawcett, Donata Orioli, Hiva Fassihi, Alan R. Lehmann   +4 more
wiley   +1 more source

Diversity and functional characterization of HNH endonucleases encoded by lactococcal <i>Skunavirus</i> phages. [PDF]

Microb Genom
Yu JH, Cambillau C, Lugli GA, Ventura M, Nauta A, Mahony J, van Sinderen D.   +6 more
europepmc   +1 more source

Evolution of a phage RuvC endonuclease for resolution of both Holliday and branched DNA junctions [PDF]

, 2005
Fiona A. Curtis, Patricia Reed, Gary J. Sharples   +2 more
openalex   +1 more source

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Endonuclease V of Escherichia coli.

, 1977
F T Gates, Stuart Linn
openalex   +1 more source

Heterologous plastoquinone production using a newly identified O2‐dependent cyanobacterial hydroxylase

The FEBS Journal, EarlyView.
In this study, we confirm that PlqH is the hydroxylase operating in plastoquinone biosynthesis in photosynthetic cyanobacteria (Cyanobacteriia). Our phylogenetic analyses demonstrate that cyanobacterial PlqH homologues originated from hydroxylases involved in ubiquinone biosynthesis in bacteria. Plastoquinone production in Escherichia coli was achieved
Morgane Roger‐Margueritat, Margot Beltran, Juliette Schnoebelen, Laura Flandrin, Wafa Rezali, Eline Michel, Sophie S. Abby, Fabien Pierrel   +7 more
wiley   +1 more source

Structure and function of the nairovirus cap-snatching endonuclease. [PDF]

Nucleic Acids Res
Kuang W, Tian Z, Zhang G, Wu F, Li J, Tang J, Zhang H, Zhuo X, Hu Z, Wang M, Zhao H, Deng Z.   +11 more
europepmc   +1 more source

Conformational Modification of Serpins Transforms Leukocyte Elastase Inhibitor into an Endonuclease Involved in Apoptosis

, 2007
Laura Padrón-Barthe, Chloé Leprêtre, Elisabeth Martin, Marie‐France Counis, Alicia Torriglia   +4 more
openalex   +2 more sources