Results 51 to 60 of about 82,787 (343)

An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase

open access: yesActa Crystallographica Section D: Biological Crystallography, 2015
The crystal and solution structures of the T. thermophilus NlpC/P60 d,l-endopeptidase as well as the co-crystal structure of its N-terminal LysM domains bound to chitohexaose allow a proposal to be made regarding how the enzyme recognizes peptidoglycan.
Jaslyn E. M. M. Wong   +8 more
semanticscholar   +1 more source

Multiple sclerosis risk variants influence the peripheral B‐cell compartment early in life in the general population

open access: yesEuropean Journal of Neurology, Volume 30, Issue 2, Page 434-442, February 2023., 2023
Polygenic risk for MS associates with changes in the peripheral B‐cell compartment of children in the general population. A MS‐PRS was significantly associated with lower relative, but not absolute, naive B‐cell numbers and higher frequencies and absolute numbers of CD27+ memory B cells.
Casper L. de Mol   +8 more
wiley   +1 more source

A Systematic Approach to the Comparison of Cost Efficiency of Endopeptidases for the Hydrolysis of Atlantic Salmon (Salmo salar) By-Products

open access: yesFood Technology and Biotechnology, 2016
The hydrolytic and cost efficiencies of five endopeptidases (Alcalase 2.4L, Corolase 7089, Neutrase 0.8L, Promod 671L and Protex 7L) to hydrolyze Atlantic salmon by-products were compared at standardized activity levels based on a casein assay.
Tone Aspevik   +2 more
doaj   +1 more source

Sonic Hedgehog Is a Member of the Hh/DD-Peptidase Family That Spans the Eukaryotic and Bacterial Domains of Life. [PDF]

open access: yes, 2018
Sonic Hedgehog (Shh) coordinates Zn2+ in a manner that resembles that of peptidases. The ability of Shh to undergo autoproteolytic processing is impaired in mutants that affect the Zn2+ coordination, while mutating residues essential for catalytic ...
Roelink, Henk
core   +3 more sources

Activity Gel Analysis of Endopeptidases in Rose Petals

open access: yesHorticultural Plant Journal, 2016
Poor resolution for the identification of endopeptidase (EP) activity in activity gel assays is a critical issue in the analysis of the postharvest physiology of rose petals. In this paper, major factors influencing EP activity gel assays were evaluated.
Xiting Zhao   +4 more
doaj   +1 more source

Magnesium rescues the morphology of Bacillus subtilis mreB mutants through its inhibitory effect on peptidoglycan hydrolases

open access: yesScientific Reports, 2022
Cell wall homeostasis in bacteria is tightly regulated by balanced synthesis and degradation of peptidoglycan (PG), allowing cells to expand their sacculus during growth while maintaining physical integrity.
Benoit Tesson   +5 more
doaj   +1 more source

Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process [PDF]

open access: yes, 2017
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition and adsorption to the cell surface. The irreversible adherence followed by genome material ejection into host cell cytoplasm must be preceded by the passage ...
Briers, Yves   +4 more
core   +1 more source

Endopeptidases and prohormone processing

open access: yesBioscience Reports, 1990
Peptide hormones and peptide transmitters are generated from polypeptide precursors by specific cleavage reactions which take place principally at sites formed by single or paired basic residues. Not all the possible cleavage sites are utilised, however, and the degree of processing of many propeptides has been found to vary according to the tissue of ...
Nigel J. Darby, D. G. Smyth
openaire   +3 more sources

Metabolism of renin-angiotensin and enkephalin in human follicular fluid: An experimental study

open access: yesInternational Journal of Reproductive BioMedicine, 2022
Background: The relationship between the biochemical characteristics of follicular fluid (FF), oocyte quality and embryonic development has not yet been elucidated.
Maria Victoria Rodríguez Gallego   +5 more
doaj   +1 more source

Neutral endopeptidase inhibition and the natriuretic peptide system: an evolving strategy in cardiovascular therapeutics.

open access: yesEuropean Heart Journal, 2013
Hypertension and heart failure (HF) are common diseases that, despite advances in medical therapy, continue to be associated with high morbidity and mortality. Therefore, innovative therapeutic strategies are needed.
S. Mangiafico   +4 more
semanticscholar   +1 more source

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