Results 41 to 50 of about 154,667 (281)
Engineering a novel endopeptidase based on SARS 3CLpro
BioTechniques, 2009 A 3C-like protease (3CLpro) from the severe acute respiratory syndrome–coronavirus (SARS-CoV) is required for viral replication, cleaving the replicase polyproteins at 11 sites with the conserved Gln↓(Ser, Ala, Gly) sequences. In this study, we developed
Chih-Jung Kuo +3 more
doaj +1 more source
Food Technology and Biotechnology, 2016 The hydrolytic and cost efficiencies of five endopeptidases (Alcalase 2.4L, Corolase 7089, Neutrase 0.8L, Promod 671L and Protex 7L) to hydrolyze Atlantic salmon by-products were compared at standardized activity levels based on a casein assay.
Tone Aspevik +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Activity Gel Analysis of Endopeptidases in Rose Petals
Horticultural Plant Journal, 2016 Poor resolution for the identification of endopeptidase (EP) activity in activity gel assays is a critical issue in the analysis of the postharvest physiology of rose petals. In this paper, major factors influencing EP activity gel assays were evaluated.
Xiting Zhao +4 more
doaj +1 more source
Metabolism of renin-angiotensin and enkephalin in human follicular fluid: An experimental study
International Journal of Reproductive BioMedicine, 2022 Background: The relationship between the biochemical characteristics of follicular fluid (FF), oocyte quality and embryonic development has not yet been elucidated.
Maria Victoria Rodríguez Gallego +5 more
doaj +1 more source
The study of a new and specific proline cleaving peptidase from bovine serum [PDF]
, 2003 Prolyl oligopeptidase is a serine peptidase characterised by oligoendopeptidase activity. Definitive evidence for the discrete biological role of prolyl oligopeptidase remains unknown, though its role in the maturation and degradation of peptide hormones
Collins, Patrick
core
Changes in the endopeptidase pattern of wheat leaves during senescence
, 1985 Peptide hydrolase activities present in young and senescing flag leaves of wheat (Triticum aestivum L.) were fractionated on DEAE-cellulose columns. Part of the endopeptidase activity was not bound to DEAE-cellulose at pH 7.5 (peak I) and had a broad pH ...
Keist, Marcel, Feller, Urs
core +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Identification of Fibrinolytic Activity in Iranian Vipera Lebetina Venom
Journal of Mazandaran University of Medical Sciences, 2020 Background and purpose: Vipera lebetina lives in different areas in Iran, and its venom contains a variety of proteins with coagulant and anticoagulant activities. Fibrinolytic enzymes could have a therapeutic role in dissolution of blood clots, so, this
Zohreh Amoozgari +3 more
doaj
Metallopeptidases of Toxoplasma gondii: in silico identification and gene expression
Parasite, 2018 Metallopeptidases are a family of proteins with domains that remain highly conserved throughout evolution. These hydrolases require divalent metal cation(s) to activate the water molecule in order to carry out their catalytic action on peptide bonds by ...
Escotte-Binet Sandie +6 more
doaj +1 more source