Results 131 to 140 of about 46,663 (296)

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Cell‐Type‐Specific and Variety‐Specific Responses to Salt Stress in Wheat Root Revealed by Single‐Cell Transcriptomics

Plant Biotechnology Journal, EarlyView.
ABSTRACT Soil salinization threatens the yield and quality of wheat. Roots are critical for the salt stress response, yet their cell‐type‐specific mechanisms remain unclear. We conducted the first single‐nucleus RNA sequencing analysis of wheat root tips from salt‐sensitive (CS) and ‐tolerant (DK) varieties under salt stress, profiling 188 270 high ...
Lin Du, Wenqiu Pan, Yali Song, Fuyan Liu, Yanzhe Jia, Cai Wei, Xinchun Li, Yong Hou, Xiaojun Nie, Hai‐Xi Sun, Jingmin Kang   +10 more
wiley   +1 more source

Neutral endopeptidase expression in mesangial cells [PDF]

, 2003
Fabiana Ebihara, Giovana Seno Di Marco, María A. Juliano, Dulce Elena Casarini   +3 more
openalex   +1 more source

Genome and Single‐Cell Transcriptome Reveal the Evolution of Holoparasitic Plants: A Case Study of Cistanche deserticola

Plant Biotechnology Journal, EarlyView.
ABSTRACT The Orobanchaceae family, the largest group of parasitic plants, spans a complete spectrum from autotrophic to holoparasitic species. As a typical endangered holoparasitic species within this family, Cistanche deserticola is a parasitic plant that is widely harvested for traditional medicine in desertic regions, and of growing importance as a ...
Xinke Zhang, Yujing Miao, Yuanyuan Xing, Guoshuai Zhang, Meiqiao Zhang, Chris J. Thorogood, Shilin Chen, Linfang Huang   +7 more
wiley   +1 more source

Binding Mode Knowledge of New Possible Anti-Hypertensive Compounds Designed In Silico Using Neutral Endopeptidase (NEP) as a Target

, 2020
Emilio Lamazares, Yudith Cañizares-Carmenate, Juan A. Castillo‐Garit, Karel Mena‐Ulecia   +3 more
openalex   +2 more sources

A stage‐dependent seed defense response to explain efficient seed transmission of Xanthomonas citri pv. fuscans to common bean

Plant, Cell &Environment, EarlyView.
Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse, Łukasz Paweł Tarkowski, Martial Briand, David Lalanne, Nicolas W. G. Chen, Matthieu Barret, Jerome Verdier   +6 more
wiley   +1 more source

Characterization of the Active Site and Insight into the Binding Mode of the Anti-angiogenesis Agent Fumagillin to the Manganese(II)-Loaded Methionyl Aminopeptidase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2005
EPR spectra were recorded for methionine aminopeptidase from Escherichia coli (EcMetAP-I) samples (~2.5 mM) to which one and two equivalents of Mn(II) were added (the latter is referred to as [MnMn(EcMetAP-I)]).
Bennett, Brian, Brown, Robert S., D\u27Souza, Ventris M., Holz, Richard C.   +3 more
core   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Purification and Characterization of Four New Cysteine Endopeptidases From Fruits of Bromelia pinguin L. Grown in Cuba [PDF]

, 2007
Juan Abreu Payrol, Walter David Obregón, Stephen J. Trejo, Néstor O. Caffini   +3 more
openalex   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source