Results 151 to 160 of about 62,083 (343)

Deletion of a Pax1 Sex‐Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice

JOR SPINE, Volume 9, Issue 2, June 2026.
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody, Emma M. Wade, Shuji Mizumoto, Jeremy McCallum‐Loudeac, Megan J. Wilson   +4 more
wiley   +1 more source

Characterization of the Active Site and Insight into the Binding Mode of the Anti-angiogenesis Agent Fumagillin to the Manganese(II)-Loaded Methionyl Aminopeptidase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2005
EPR spectra were recorded for methionine aminopeptidase from Escherichia coli (EcMetAP-I) samples (~2.5 mM) to which one and two equivalents of Mn(II) were added (the latter is referred to as [MnMn(EcMetAP-I)]).
Bennett, Brian, Brown, Robert S., D\u27Souza, Ventris M., Holz, Richard C.   +3 more
core   +1 more source

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque, Aymeric Jacquemin, Delphine Girlich, Rémy A. Bonnin, Laurent Dortet   +4 more
wiley   +1 more source

Actin proteolysis during ripening of dry fermented sausages at different pH values [PDF]

, 2017
Berardo, Alberto, De Maere, H, De Smet, Stefaan, Devreese, Bart, Leroy, F, Stavropoulou, DA, Van Royen, G   +6 more
core   +1 more source

Controlling the Precision-Recall Tradeoff in Differential Dependency Network Analysis [PDF]

, 2013
Graphical models have gained a lot of attention recently as a tool for learning and representing dependencies among variables in multivariate data.
Clark, Vincent P., Niculescu-Mizil, Alexandru, Ostroff, Rachel, Oyen, Diane, Stewart, Alex   +4 more
core  

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro, J. Carballo, M. C. Pasten, C. A. Gallo, E. Albertini, V. Echenique   +5 more
wiley   +1 more source

The important role of matrix metalloproteinases in nematode parasites

Helminthologia, 2014
Azami M., Anvarinejad M., Jamshidian Ghalesefidi M.   +2 more
doaj   +1 more source

Plasma EDA2R and Risk of Cardiovascular Diseases and All‐Cause Mortality: Analysis of the UK Biobank Cohort

Clinical Cardiology, Volume 49, Issue 5, May 2026.
In this large‐scale UK Biobank analysis, elevated plasma EDA2R was associated with a 74% higher risk of cardiovascular disease and a 177% higher risk of all‐cause mortality, with a 7.2‐year loss in life expectancy in the highest EDA2R group, suggesting its potential as a prognostic biomarker and therapeutic target.
Ziqing Ruan, Jiabin Tu, Hongli Xu, Yupeng Zhi, Chun Chen, Kaiyang Lin, Yansong Guo   +6 more
wiley   +1 more source

Nitrogen metabolism and remobilization during senescence [PDF]

, 2017
Senescence is a highly organized and well‐regulated process. As much as 75% of total cellular nitrogen may be located in mesophyll chloroplasts of C3‐plants.
Feller, Urs, Hörtensteiner, Stefan
core  

Liver Gene Therapy in Fabry Disease Mice With Low Doses of rAAV2/8 Expressing a Codon‐Optimized hGLA cDNA Results in Long‐Term Disease Correction

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
AAV‐mediated gene therapy targets the liver to produce and secrete into circulation functional α‐Gal A, which is taken up by tissues to reduce glycosphingolipid accumulation and prevent disease progression in juvenile Fabry mice, even at low AAV doses. ABSTRACT Fabry disease (FD) is an X‐linked lysosomal storage disorder caused by mutations in the GLA ...
Himanshi Saxena, Rossana Domenis, Giulia Romano, Jessica Biasizzo, Martina Ferro, Dania Ferino, Antonio Vicidomini, Alessandra Iaconcig, Giulia Bortolussi, Lorena Zentilin, Andrea Dardis, Andrés F. Muro   +11 more
wiley   +1 more source