Results 171 to 180 of about 62,083 (343)

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

British Journal of Pharmacology, Volume 183, Issue 10, Page 2236-2255, May 2026.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi, Raimondo Ascione, Shazia Khan, Thomas Johnson, Eva Sammut, Vito Domenico Bruno, Daniel Baz Lopez, Carol‐Anne James, Joanna Simpson, Natalie Z. Homer, Michael Millar, Trisha Singh, Alex von Kreigsheim, Nick L. Mills, Brian R. Walker, Ruth Andrew, Scott P. Webster, Andrew Whittaker, Adrian Freeman, Gillian A. Gray   +19 more
wiley   +1 more source

Immune modulation of buffalo peripheral blood mononuclear cells by two asparaginyl endopeptidases from Fasciola gigantica

Parasites & Vectors
Background Fascioliasis is a zoonotic parasitic disease caused by Fasciola hepatica and Fasciola gigantica, which poses a serious threat to global public health and livestock farming.
Dong-Qi Wu, Yan-Feng Guo, Yu Zou, Xiao-Ting Tang, Wei-Yu Zhang, Wen-Da Di   +5 more
doaj   +1 more source

Synthesis of Prolyl Endopeptidase Inhibitors and Evaluation of Their Structure-Activity Relationships: In Vitro Inhibition of Prolyl Endopeptidase from Canine Brain.

, 1993
Heihachiro ARAI, Hiroyasu NISHIOKA, S Niwa, Takeshi YAMANAKA, Yoshiaki TANAKA, Koji Yoshinaga, Naomi KOBAYASHI, Naoyoshi Miura, Yugo IKEDA   +8 more
openalex   +2 more sources

Arabidopsis acclimation to daily environmental fluctuations converts a defense response regulator into a susceptibility factor toward Sclerotinia

New Phytologist, Volume 250, Issue 4, Page 2516-2534, May 2026.
Summary Acclimation enables plants to adjust to immediate environmental fluctuations and is therefore key to the resilience of plant disease resistance in a time of climate change. Here, we report on the acclimation of Arabidopsis thaliana quantitative immune responses against the fungal pathogen Sclerotinia sclerotiorum to daily environmental ...
Marie Didelon, Justine Sucher, Florent Delplace, Pedro Carvalho‐Silva, Matilda Zaffuto, Adelin Barbacci, Sylvain Raffaele   +6 more
wiley   +1 more source

A Bifunctional Protease Cleaves the Leader Peptide in the Biosynthesis of Class I Microviridins

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Biochemical characterization of the peptidase candidate NosP reveals bifunctional endo‐ and aminopeptidase activity in the leader peptide removal of class I microviridins from Nostoc punctiforme. The discovery of the first leader‐processing peptidase from microviridin biosynthesis may pave the way for the efficient production and bioengineering of ...
Nico Brüssow, Stella Scholz, Antje Stindt, Vincent Wiebach, Tino Damaszek, Roderich D. Süssmuth, Elke Dittmann, Martin Baunach   +7 more
wiley   +1 more source

The RipA and RipB Peptidoglycan Endopeptidases Are Individually Nonessential to Mycobacterium smegmatis

Journal of Bacteriology, 2016
Daniel J. Martinelli, M. Pavelka
semanticscholar   +1 more source

Posttranslational processing of a carboxy‐terminal propeptide containing a KDEL sequence of plant vacuolar cysteine endopeptidase (SH‐EP) [PDF]

, 1994
Takashi Okamoto, Hiroshi Nakayama, Kazuo Seta, Toshiaki Isobe, Takao Minamikawa   +4 more
openalex   +1 more source

Critical Role for Asparagine Endopeptidase in Endocytic Toll-like Receptor Signaling in Dendritic Cells [PDF]

, 2009
Fernando E. Sepulveda, Sophia Maschalidi, Renaud Colisson, Lea Heslop, Cristina Ghirelli, Emna Sakka, Ana‐Maria Lennon‐Duménil, Sebastián Amigorena, Lucien Cabanié, Bénédicte Manoury   +9 more
openalex   +1 more source

The Cytosolic Endopeptidase, Thimet Oligopeptidase, Destroys Antigenic Peptides and Limits the Extent of MHC Class I Antigen Presentation [PDF]

, 2003
Ian A. York, Annie X. Mo, Kristen Lemerise, Wanyong Zeng, Yuelei Shen, Carmela R. Abraham, Tomo Šarić, Alfred L. Goldberg, Kenneth L. Rock   +8 more
openalex   +1 more source

Specific role of two NlpC/P60 endopeptidases in cell division and membrane vesicle formation in <i>Deinococcus radiodurans</i>. [PDF]

Curr Res Microb Sci
Kamara T, Martinez G, Eugénie N, Dutertre M, Confalonieri F, Bentchikou E, Servant P.   +6 more
europepmc   +1 more source