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Subcompartments of the endoplasmic reticulum
Seminars in Cell Biology, 1992The endoplasmic reticulum (ER) is the largest continuous endomembrane structure in the cytoplasm. It may be viewed as a series of unique subcompartments. In this review, we examine the rough ER, nuclear envelope and several smooth ER subcompartments. Consideration is given to the characteristic properties and functions of the ER and its domains, and to
B M, Vertel, L M, Walters, D, Mills
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Exiting the Endoplasmic Reticulum
Traffic, 2005Vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex constitutes the initial step in protein secretion. COPII‐coated vesicles mediate the export of newly synthesized proteins from the ER, and this transport step is coupled with COPI‐mediated retrograde traffic to form a transport circuit that supports the compositional asymmetry
Joseph D, Mancias, Jonathan, Goldberg
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On the functions of the endoplasmic reticulum
Biochemical Pharmacology, 1961Abstract Ribonucleoprotein (RNP) particles were purified in a highly active state from a number of tissues of the rat. Particle yield varied considerably for different tissues but the composition of particles was fairly similar. From the early blastula stage of Psammechinus eggs active particles were also obtained, and at a higher yield than from ...
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Origin of the Endoplasmic Reticulum
Nature, 1962To propose a mechanism of origin of the endoplasmic reticulum based on a study of yeast cytology may seem presumptuous because there is no field in which so many different opinions prevail. The variety of opinions have arisen because yeasts, like all acellular (single-celled) organisms, manifest a maximal diversity of internal organization, and a ...
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Networking in the endoplasmic reticulum
Biochemical Society Transactions, 2010The network of the ER (endoplasmic reticulum) is set up by cytoskeletal control of the movement and remodelling of polygonal rings of tubules, bundles of tubules and cisternal regions. We have developed a new image analysis tool, persistency mapping, to understand the framework upon which the plant ER remodels.
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Serpinopathy and endoplasmic reticulum stress
Medical Molecular Morphology, 2005We have recently identified a novel human gene, megsin, which is a new serine protease inhibitor (serpin) predominantly expressed in the kidney. Our previous studies suggested a role of megsin in the pathogenesis of human renal diseases, but its exact biopathological significance remained unknown.
Toshio, Miyata +3 more
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2013
This chapter focuses on the endoplasmic reticulum (ER), which forms part of the endomembrane system of eukaryotic cells. It clarifies that the ER membrane is continuous with the outer nuclear membrane and encloses a space called the lumen which is continuous with the perinuclear space. It also describes ER as a dynamic system, the structure of which is
Qiuyu Wang, Chris Smith, Emma Davis
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This chapter focuses on the endoplasmic reticulum (ER), which forms part of the endomembrane system of eukaryotic cells. It clarifies that the ER membrane is continuous with the outer nuclear membrane and encloses a space called the lumen which is continuous with the perinuclear space. It also describes ER as a dynamic system, the structure of which is
Qiuyu Wang, Chris Smith, Emma Davis
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The Lipid Droplet and the Endoplasmic Reticulum
2017Lipid droplets (LDs) are often found adjacent to the endoplasmic reticulum (ER). The ER-LD association may appear morphologically similar to the prototypical membrane contact sites found between the ER and other organelles, but the functional relationship between the ER and LDs is unique in that highly hydrophobic lipid esters are transported between ...
Yuki, Ohsaki +2 more
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1992
Publisher Summary This chapter presents the current understanding of the structural elements that make up endoplasmic reticulum (ER). The primary structural elements of the ER are the molecular components such as the proteins, lipids, and ions. The secondary elements are the local organizational motifs formed by the individual components. In the case
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Publisher Summary This chapter presents the current understanding of the structural elements that make up endoplasmic reticulum (ER). The primary structural elements of the ER are the molecular components such as the proteins, lipids, and ions. The secondary elements are the local organizational motifs formed by the individual components. In the case
openaire +1 more source

