Results 211 to 220 of about 755,597 (345)

Consecutive Steps of Nucleoside Triphosphate Hydrolysis Are Driving Transport of Precursor Proteins into the Endoplasmic Reticulum [PDF]

, 1992
Klappa, Peter, Lill, Roland, Müller, Günter, Neupert, Walter, Schlenstedt, Gabriel, Wiech, Hans, Zimmermann, Richard   +6 more
core   +1 more source

CD28‐Targeted Enzyme‐Responsive Conformation‐Switching Peptide Self‐Assembly for Selective T‐Cell Acute Lymphoblastic Leukemia (T‐ALL) Therapy

Advanced Science, EarlyView.
We developed the enzyme‐responsive peptide SAp‐CD28 to selectively target CD28‐overexpressing T‐ALL cells. Following phosphatase‐mediated activation, SAp‐CD28 undergoes conformational switching and nanooligomerization, resulting in the disruption of CD28 downstream signaling.
Jun Li, Ziyu Jia, Dekun Li, Zhi‐Wen Hu, Yinghao Ding, Shengyi Zhang, Shengkun Tuo, Zhimou Yang, Huisheng Fu, Ling Wang, Man‐Di Wang   +10 more
wiley   +1 more source

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress. [PDF]

Mol Med Rep
Qiu QQ, Zhang N, Xu YY, Qin JW, Yu GF, Song XR.   +5 more
europepmc   +1 more source

Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations [PDF]

, 2016
et al,, Urano, Fumihiko
core   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Endoplasmic reticulum patterns insect cuticle nanostructure. [PDF]

J Cell Biol
Inagaki S, Wada H, Itabashi T, Itakura Y, Nakagawa R, Chen L, Murata K, Iwane AH, Hayashi S.   +8 more
europepmc   +1 more source

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

Nature Cell Biology, 2019
Amado Carreras-Sureda, Fabián Jaña, H. Urra, S. Durand, S. Durand, D. E. Mortenson, Alfredo I Sagredo, G. Bustos, G. Bustos, Younis Hazari, Eva Ramos-Fernández, M. Sassano, Philippe Pihán, A. V. Vliet, Matías González-Quiroz, Angie K Torres, Cheril Tapia‐Rojas, M. Kerkhofs, R. Vicente, R. Kaufman, N. Inestrosa, Christian González-Billault, Christian González-Billault, R. Wiseman, P. Agostinis, G. Bultynck, F. Court, G. Kroemer, J. C. Cardenas, C. Hetz   +29 more
semanticscholar   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Correction to "Potential Roles of Endoplasmic Reticulum Stress and Cellular Proteins Implicated in Diabesity". [PDF]

Oxid Med Cell Longev
europepmc   +1 more source

The interaction between endoplasmic reticulum stress and ferroptosis in ovarian diseases. [PDF]

J Ovarian Res
Xing M, Li J, Wu X, Zhang R, Li L, Liu H.   +5 more
europepmc   +1 more source