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Annals of the New York Academy of Sciences, 2007
Abstract: Stress is the imbalance of homeostasis, which can be sensed even at the subcellular level. The stress‐sensing capability of various organelles including the endoplasmic reticulum (ER) has been described. It has become evident that acute or prolonged ER stress plays an important role in many human diseases; especially those involving organs ...
BANHEGYI G +15 more
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Abstract: Stress is the imbalance of homeostasis, which can be sensed even at the subcellular level. The stress‐sensing capability of various organelles including the endoplasmic reticulum (ER) has been described. It has become evident that acute or prolonged ER stress plays an important role in many human diseases; especially those involving organs ...
BANHEGYI G +15 more
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Exiting the endoplasmic reticulum
Molecular and Cellular Endocrinology, 2001The movement of nascent proteins from sites of synthesis to final cellular or extracellular destinations involves their transport through a distinct series of vesicular compartments. Vesicle biogenesis is regulated by specific proteins and co-factors that control distinct steps including budding, transport, docking, and fusion with target membranes ...
Fred S. Gorelick, Christine A. Shugrue
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Exiting the Endoplasmic Reticulum
Traffic, 2005Vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex constitutes the initial step in protein secretion. COPII‐coated vesicles mediate the export of newly synthesized proteins from the ER, and this transport step is coupled with COPI‐mediated retrograde traffic to form a transport circuit that supports the compositional asymmetry
Joseph D. Mancias, Jonathan Goldberg
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Subcompartments of the endoplasmic reticulum
Seminars in Cell Biology, 1992The endoplasmic reticulum (ER) is the largest continuous endomembrane structure in the cytoplasm. It may be viewed as a series of unique subcompartments. In this review, we examine the rough ER, nuclear envelope and several smooth ER subcompartments. Consideration is given to the characteristic properties and functions of the ER and its domains, and to
Barbara M. Vertel +2 more
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On the functions of the endoplasmic reticulum
Biochemical Pharmacology, 1961Abstract Ribonucleoprotein (RNP) particles were purified in a highly active state from a number of tissues of the rat. Particle yield varied considerably for different tissues but the composition of particles was fairly similar. From the early blastula stage of Psammechinus eggs active particles were also obtained, and at a higher yield than from ...
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Networking in the endoplasmic reticulum
Biochemical Society Transactions, 2010The network of the ER (endoplasmic reticulum) is set up by cytoskeletal control of the movement and remodelling of polygonal rings of tubules, bundles of tubules and cisternal regions. We have developed a new image analysis tool, persistency mapping, to understand the framework upon which the plant ER remodels.
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Origin of the Endoplasmic Reticulum
Nature, 1962To propose a mechanism of origin of the endoplasmic reticulum based on a study of yeast cytology may seem presumptuous because there is no field in which so many different opinions prevail. The variety of opinions have arisen because yeasts, like all acellular (single-celled) organisms, manifest a maximal diversity of internal organization, and a ...
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Protein degradation in the endoplasmic reticulum
Cell, 1990Etat actuel des connaissances sur le processus de degradation des proteines au sein du reticulum endoplasmique: interet porte aux proteines membranaires et proteines ...
Klausner R. , D., SITIA, ROBERTO
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2010
Publisher Summary Endoplasmic reticulum (ER) is a highly convoluted, netlike meshwork that extends throughout the cytoplasm. It is composed of a single membrane and constitutes more than half of the total membrane of the cell. The architecture of the ER is dynamic as it varies from cell to cell and changes throughout the cell cycle.
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Publisher Summary Endoplasmic reticulum (ER) is a highly convoluted, netlike meshwork that extends throughout the cytoplasm. It is composed of a single membrane and constitutes more than half of the total membrane of the cell. The architecture of the ER is dynamic as it varies from cell to cell and changes throughout the cell cycle.
openaire +2 more sources