Results 211 to 220 of about 5,201 (300)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Frequency and time domain ¹⁹F ENDOR spectroscopy: role of nuclear dipolar couplings to determine distance distributions.

Phys Chem Chem Phys
Kehl A, Sielaff L, Remmel L, Rämisch ML, Bennati M, Meyer A.   +5 more
europepmc   +1 more source

Indirect Detection of the Protons in and around Biradicals and their Mechanistic Role in MAS-DNP. [PDF]

J Phys Chem Lett
Chatterjee S, Scott FJ, Sigurdsson ST, Venkatesh A, Mentink-Vigier F.   +4 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Transition metal coordination to degradation products in battery electrolytes revealed by NMR and EPR spectroscopy.

Energy Environ Sci
Allen JP, Szczuka C, Jónsson E, Eichel RA, Granwehr J, Grey CP.   +5 more
europepmc   +1 more source

Context-dependent MAN1A1 protein expression in metastatic breast cancer progression predicts patient survival. [PDF]

BMC Cancer
Jenkinson NM, Hughes S, Baras A, Meeker A, Argani P, Glunde K.   +5 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Pulsed EPR Methods in the Angstrom to Nanometre Scale Shed Light on the Conformational Flexibility of a Fluoride Riboswitch. [PDF]

Angew Chem Int Ed Engl
Remmel L, Meyer A, Ackermann K, Hagelueken G, Bennati M, Bode BE.   +5 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source