Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Short‑term outcomes of minimally invasive endoscopic onlay repair for diastasis recti and ventral hernia repair: a systematic review and meta‑analysis. [PDF]
Brucchi F +3 more
europepmc +1 more source
Ethical Foreground and Background in Adult Educator Work
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Recent advances in quantifying protein conformational ensembles with dipolar EPR spectroscopy. [PDF]
Dastvan R, Stoll S.
europepmc +1 more source
The Electronic Spin State of Diradicals Obtained from the Nuclear Perspective: The Strange Case of Chichibabin Radicals. [PDF]
Moise G +7 more
europepmc +1 more source
From two to one: resolving CO binding in acetyl-CoA synthase. [PDF]
Poire D +12 more
europepmc +1 more source
In situ learning-based spin engineering of pulsed dynamic nuclear polarization. [PDF]
Jensen FV +8 more
europepmc +1 more source
Radical Anions of Porphyrin Molecular Wires: Delocalization and Dynamics. [PDF]
Hergenhahn J +7 more
europepmc +1 more source

