Results 101 to 110 of about 5,581 (192)
Ribonucleases and their Applications
, 2016 Ribonuclease (RNase) is a type of nuclease that catalyzes degradation of RNA into smaller components. RNase can be classified into two broader categories namely endoribonucleases and exoribonucleases on the basis of their site of action.
Kumar, Rakesh; Department of Biotechnology, Himachal Pradesh University +4 more
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Identification of unknown functions in Lassa virus L protein
, 2010 The central domain of the 200-kDa Lassa virus L protein is a putative RNA-dependent RNA polymerase. N- and C-terminal domains may harbor enzymatic functions important for viral mRNA synthesis, including capping enzymes or cap-snatching endoribonucleases.
Lelke, Michaela
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Metal ions govern coronavirus endoribonuclease activity
Nucleic Acids ResearchAbstract Coronavirus nonstructural protein 15 (nsp15) is an endoribonuclease that restricts viral double-stranded RNA (dsRNA) accumulation in the cytosol to evade host immunity. Given the co-localization of nsp15 and replicating viral RNA, the mechanism controlling nsp15 activity is essential, yet poorly understood.
Xionglue Wang +4 more
openaire +2 more sources
Identifizierung unbekannter Funktionen im Lassa-Virus L-Protein
, 2010 The central domain of the 200-kDa Lassa virus L protein is a putative RNA-dependent RNA polymerase. N- and C-terminal domains may harbor enzymatic functions important for viral mRNA synthesis, including capping enzymes or cap-snatching endoribonucleases.
Lelke, Michaela
core
, 2017 Dicer, a member of the RNase III family of endoribonucleases, has an important role in regulating methylation of CpG islands in mammal cancer cells. However, the underlying mechanism of action remains unclear.
Wenhua Huang +5 more
core +1 more source
, 2017 Pancreatic-type ribonucleases (ptRNases) comprise a class of highly conserved secretory endoribonucleases in vertebrates. The prototype of this enzyme family is ribonuclease 1 (RNase 1).
Chelcie H. Eller +2 more
core +1 more source
VapCs of Mycobacterium tuberculosis Cleave RNAs Essential for Translation:VapCs of M. tuberculosis cleave tRNAs and 23S rRNA [PDF]
, 2016 The major human pathogen Mycobacterium tuberculosis can survive in the host organism for decades without causing symptoms. A large cohort of Toxin-Antitoxin (TA) modules contribute to this persistence.
Gerdes, Kenn +3 more
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Basis for regulated RNA cleavage by functional
, 2001 RNase L and Ire1p are members of a superfamily of regulated endoribonucleases that play essential roles in mediating diverse types of cellular stress responses.
Peter Walter +4 more
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