The Genetic Basis of Color Polymorphism in the Orb‐Web Spider Gasteracantha cancriformis
This study investigates the genetic basis of coloration in the polymorphic spider Gasteracantha cancriformis using RNA‐seq data from different female color morphs. We assembled a reference transcriptome and identified differentially expressed genes associated with known pigmentation pathways, including carotenoids, melanin, ommochromes, and pteridines.
Paula Torres‐Quintero +3 more
wiley +1 more source
Structural basis for human mitochondrial tRNA maturation
The human mitochondrial genome is transcribed into two RNAs, containing mRNAs, rRNAs and tRNAs, all dedicated to produce essential proteins of the respiratory chain. The precise excision of tRNAs by the mitochondrial endoribonucleases (mt-RNase), P and Z,
Vincent Meynier +9 more
doaj +1 more source
Type 2 Diabetes From the Perspective of Telomere Biology
This graphical abstract illustrates the bidirectional relationship between the telomere/telomerase system and T2DM: telomere attrition contributes to pancreatic β‐cell dysfunction and insulin resistance through mechanisms such as oxidative stress and apoptosis, while T2DM‐related hyperglycemia and chronic inflammation further exacerbate telomere damage.
Hongye Cao +3 more
wiley +1 more source
The role of ribonucleases in regulating global mRNA levels in the model organism Thermus thermophilus HB8 [PDF]
BACKGROUND: RNA metabolism, including RNA synthesis and RNA degradation, is one of the most conserved biological systems and has been intensively studied; however, the degradation network of ribonucleases (RNases) and RNA substrates is not fully ...
Akeo Shinkai +7 more
core +1 more source
Structure and variation of CRISPR and CRISPR-flanking regions in deleted-direct repeat region Mycobacterium tuberculosis complex strains [PDF]
Sequences S1âS6.
Anna Luria +9 more
core +3 more sources
Coupling immunity and programmed cell suicide in prokaryotes: Life-or-death choices [PDF]
Host-pathogen arms race is a universal, central aspect of the evolution of life. Most organisms evolved several distinct yet interacting strategies of anti-pathogen defense including resistance to parasite invasion, innate and adaptive immunity, and ...
Abudayyeh +94 more
core +1 more source
RNA/aTNA chimeras: RNAi effects and nucleases resistance of single and double stranded RNAs [PDF]
The RNA interference pathway (RNAi) is a specific and powerful biological process, triggered by small non-coding RNA molecules and involved in gene expression regulation. In this work, we explored the possibility of increasing the biological stability of
Alagia, Adele +2 more
core +2 more sources
Base Pairing Interaction between 5′- and 3′-UTRs Controls icaR mRNA Translation in Staphylococcus aureus [PDF]
The presence of regulatory sequences in the 3′ untranslated region (3′-UTR) of eukaryotic mRNAs controlling RNA stability and translation efficiency is widely recognized.
Bitarte, Nerea +7 more
core +2 more sources
YoeB-ribosome structure: a canonical RNase that requires the ribosome for its specific activity [PDF]
As a typical endoribonuclease, YoeB mediates cellular adaptation in diverse bacteria by degrading mRNAs on its activation. Although the catalytic core of YoeB is thought to be identical to well-studied nucleases, this enzyme specifically targets mRNA ...
Chen, Yun +6 more
core
The endoribonuclease YbeY is linked to proper cellular morphology and virulence in 2 Brucella abortus [PDF]
The endoribonuclease YbeY is one of the most well conserved proteins across the kingdoms of life. In the present study, we demonstrate that YbeY in Brucella abortus is linked to a variety of important activities, including proper cellular morphology ...
Budnick, James A. +5 more
core +1 more source

