Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1
Plant, Cell &Environment, Volume 48, Issue 6, Page 4227-4244, June 2025.ABSTRACT Decapping 5′‐3′ exoribonucleases from the DXO/Rai1 family are highly conserved among eukaryotes and exhibit diverse enzymatic activities depending on the organism. The biochemical and structural properties of the plant DXO1 differ from the yeast and animal counterparts, which is reflected in the in vivo functions of this enzyme.
Monika Zakrzewska‐Placzek +5 more
wiley +1 more source
Post-transcriptional control by bacteriophage T4: mRNA decay and inhibition of translation initiation [PDF]
, 2010 Over 50 years of biological research with bacteriophage T4 includes notable discoveries in post-transcriptional control, including the genetic code, mRNA, and tRNA; the very foundations of molecular biology.
Miller, Eric S, Uzan, Marc
core +3 more sources
CRISPRmap: an automated classification of repeat conservation in prokaryotic adaptive immune systems
Nucleic Acids Research, 2013 Central to Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-Cas systems are repeated RNA sequences that serve as Cas-protein–binding templates.
Sita Lange +4 more
semanticscholar +1 more source
Journal of Biological Chemistry, 1983 Endoribonuclease VII, a novel endoribonuclease from calf thymus, was identified and purified by us. The purified enzyme has Mr = 74,000; its homogeneity was checked by analysis in polyacrylamide gels (both in the presence and in the absence of sodium dodecyl sulfate). The nuclease cleaves poly(U) and poly(C) while other single-stranded homopolyribo- as
Michael Bachmann +2 more
openaire +3 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2005 The spindle midzone, a conspicuous network of antiparallel interdigitating nonkinetochore microtubules between separating chromosomes, plays a crucial role in regulating the initiation and completion of cytokinesis.
Changjun Zhu, Wei Jiang
semanticscholar +1 more source
Fragmentation of tRNA in Phytophthora infestans asexual life cycle stages and during host plant infection [PDF]
, 2014 The oomycete Phytophthora infestans possesses active RNA silencing pathways, which presumably enable this plant pathogen to control the large numbers of transposable elements present in its 240 Mb genome.
Avrova, Anna +7 more
core +2 more sources
RNA/aTNA chimeras: RNAi effects and nucleases resistance of single and double stranded RNAs [PDF]
, 2014 The RNA interference pathway (RNAi) is a specific and powerful biological process, triggered by small non-coding RNA molecules and involved in gene expression regulation. In this work, we explored the possibility of increasing the biological stability of
Alagia, Adele +2 more
core +2 more sources
in vitro processing of HeLa cell preribosomes by a nucleolar endoribonuclease [PDF]
, 1972 Marc-Édouard Mirault, Klaus Scherrer
openalex +1 more source
Toxins of Prokaryotic Toxin-Antitoxin Systems with Sequence-Specific Endoribonuclease Activity
Toxins, 2017 Protein translation is the most common target of toxin-antitoxin system (TA) toxins. Sequence-specific endoribonucleases digest RNA in a sequence-specific manner, thereby blocking translation.
H. Masuda, M. Inouye
semanticscholar +1 more source
Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity
Oncotarget, 2015 IRE1α is an endoplasmic reticulum (ER)-resident transmembrane signaling protein and a cellular stress sensor. The protein harbors a cytosolic dual kinase/endoribonuclease activity required for adaptive responses to micro-environmental changes. In an orthotopic xenograft model of human glioma, invalidation of IRE1α RNase or/and kinase activities ...
Jabouille, Arnaud +11 more
openaire +5 more sources