Results 121 to 130 of about 5,190 (143)

Endoribonuclease activities of Trypanosoma brucei mitochondria

Molecular and Biochemical Parasitology, 2002
RNA editing in kinetoplastids is a type of post-transcriptional processing that changes mitochondrial mRNA sequences by the addition or deletion of uridines. Multiple enzymatic activities, such as endoribonuclease and RNA ligase, are associated with this process and exist in a multienzyme complex.
Reza, Salavati, Aswini K, Panigrahi, Barbara A, Morach, Setareh S, Palazzo, Robert P, Igo, Kenneth, Stuart   +5 more
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A microsomal endoribonuclease from rat liver

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1980
An endoribonuclease has been purified about 320-fold from the microsomes of rat liver. The enzyme had an apparent molecular weight of 54 000-58 000 and produced oligonucleotides, each consisting of 3-7 nucleotides from poly(A) and poly(U). No mononucleotide was obtained by the enzymatic hydrolysis of poly(A) and poly(U) under standard coditions.
H, Kumagai, K, Igarashi, T, Takayama, K, Watanabe, K, Sugimoto, S, Hirose   +5 more
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Overview of the Leishmaniavirus endoribonuclease and functions of other endoribonucleases affecting viral gene expression

The Journal of Experimental Zoology, 1998
Leishmaniaviruses (LRV) are double-stranded RNA viruses that persistently infect some strains of the protozoan parasite Leishmania. The identification of a short viral RNA transcript led to our discovery of an endoribonuclease activity of the LRV capsid protein.
K J, MacBeth, J L, Patterson
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Nucleotide binding architecture for secreted cytotoxic endoribonucleases

Biochimie, 2013
Vertebrate secreted RNases are small cationic protein endowed with an endoribonuclease activity that belong to the RNase A superfamily and display diverse cytotoxic activities. In an effort to unravel their mechanism of action, we have analysed their nucleotide binding recognition patterns. General shared features with other nucleotide binding proteins
Ester, Boix, Jose A, Blanco, M Victòria, Nogués, Mohammed, Moussaoui   +3 more
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Endoribonuclease activity associated with animal RNA viruses

Journal of Virology, 1978
A specific endoribonucleolytic activity was detected when detergent-lysed vesicular stomatitis of Sendai virus was incubated with the precursor to Escherichia coli tRNA Tyr. The cleavage products produced and the characteristics of the reaction were similar to those previously reported for human KB cell RNase NU.
D, Kolakofsky, S, Altman
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Designing Efficient and Specific Endoribonuclease-Prepared siRNAs

2012
RNA interference (RNAi) has grown to be one of the main techniques for loss-of-function studies, leading to the elucidation of biological function of genes in various cellular systems and model organisms. While for many invertebrates such as Drosophila melanogaster (D. melanogaster) and Caenorhabditis elegans (C.
Surendranath V, Theis M, Habermann BH, Buchholz F.   +3 more
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Endoribonucleases – enzymes gaining spotlight in mRNA metabolism

The FEBS Journal, 2010
The efficient turnover of messenger RNA represents an important mechanism that allows the cell to control gene expression. Until recently, the mechanism of mRNA decay was mainly attributed to exonucleases, comprising enzymes that degrade RNAs from the ends of the molecules.
Wai Ming, Li, Tavish, Barnes, Chow H, Lee   +2 more
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Bacteriophage T4 RegB Endoribonuclease

2001
Publisher Summary The development of bacteriophage T4 is largely determined by a precisely coordinated subversion of the host RNA polymerase to permit initiation from different classes of T4-specific promoters. The synthesis, in cascade, of regulatory elements that modify the transcription apparatus, ensures the temporal ordering of the developmental
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A calcium dependent endoribonuclease from Trypanosoma congolense cytoplasm

Molecular and Biochemical Parasitology, 1984
A major endoribonuclease whose activity depends on the presence of calcium ions was isolated from the cytoplasm of Trypanosoma congolense. Like the Ca2+-dependent endoribonuclease of T. brucei cytoplasm, this enzyme degraded poly(A) preferentially but also degraded to a lesser extent poly(U), tRNA and rRNA to give 5'-phosphoribosyl oligonucleotides ...
G O, Gbenle, E O, Akinrimisi
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Purification and characterization of a novel mammalian endoribonuclease

Journal of Cellular Biochemistry, 2005
AbstractEndonuclease‐mediated mRNA decay appears to be a common mode of mRNA degradation in mammalian cells, but yet only a few mRNA endonucleases have been described. Here, we report the existence of a second mammalian endonuclease that is capable of cleaving c‐myc mRNA within the coding region in vitro.
Kirk, Bergstrom, Joel C, Urquhart, Alaeddin, Tafech, Erin, Doyle, Chow H, Lee   +4 more
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