Results 41 to 50 of about 20,058 (181)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Influence of training and competitive sessions on peripheral β-endorphin levels in training show jumping horses [PDF]

Veterinary World, 2017
Aim: To investigate the effects of training sessions on circulating β-endorphin changes in sport horses before and after competition and to ascertain whether competition would affect this response.
Cristina Cravana, P. Medica, G. Ragonese, E. Fazio   +3 more
doaj   +1 more source

Changes in Plasma Beta-Endorphin Levels in Stage III–IV Nasopharyngeal Carcinoma Patients Post World Health Organization 3-Step Analgesic Ladder Therapy

Asian Journal of Oncology, 2022
Introduction Nasopharyngeal carcinoma (NPC) is the most common malignancy in the field of otorhinolaryngology, and chronic pain is identical with this malignancy.
Diar Mia Ardani, Bakti Surarso, Nyilo Purnami, Rizka Fathoni Perdana   +3 more
doaj   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Effects of daytime variation on pain intensity and analgesic requirement after cesarean section: a retrospective and prospective study

Annals of Medicine
Background This study compared postoperative pain and analgesic requirements in women who underwent cesarean section (CS) in the morning and afternoon.Summary background data It is unclear whether there was difference in postoperative pain intensity and ...
Bin Shu, Ai Yan, Yonggang Liang, Jianrong He, Jie Chen, Xuehan Chen, He Huang, Guangyou Duan   +7 more
doaj   +1 more source

The Role of Beta-Endorphin in Food Deprivation-Mediated Increases in Food Intake and Binge-Eating

Brain Sciences, 2023
Food deprivation and binge eating represent significant public health concerns. Previous studies have implicated that hypothalamic opioids are affected following food deprivation.
Laica Tolentino, Asif Iqbal, Shafiqur Rahman, Kabirullah Lutfy   +3 more
doaj   +1 more source

Beyond Bouncing Back: Exploring Undergraduate Dental Professional Students' Perceptions of Resilience

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The first signs of mental health issues in dentistry manifest as early as undergraduate training, thus it is essential to delve into the concept of resilience to equip those studying and working in dentistry with the resources to cultivate a positive mindset.
Vaida Kaunaite, Marina Harris
wiley   +1 more source

Effects of endorphin massage on B-endorphin level and Edinburgh Postnatal Depression Scale (EPDS) score in women with postpartum blues

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Purpose: This study aimed to investigate the effects of endorphin massage on B-endorphin level and EPDS score in women with postpartum blues. Material and Methods: Twenty postpartum women volunteered for the study.
Hidayati Hidayati, Wisnu Barlianto, Siti Candra Windu Baktiyani   +2 more
doaj  

Use of Platelet‐Rich Fibrin (PRF) on Palatal Wound Healing: A Narrative Review With Clinical Recommendations

Journal of Periodontal Research, EarlyView.
Based on the available evidence, the application of platelet‐rich fibrin (PRF) following free gingival graft (FGG) and subepithelial connective tissue graft (SCTG) harvesting appears to be a promising approach for enhancing wound healing, minimizing postoperative complications, and reducing analgesic consumption. ABSTRACT This clinical narrative review
Nima Farshidfar, Paras Ahmad, Nathan Estrin, Yufeng Zhang, Richard J. Miron   +4 more
wiley   +1 more source

The spinal microglial IL-10/β-endorphin pathway accounts for cinobufagin-induced mechanical antiallodynia in bone cancer pain following activation of α7-nicotinic acetylcholine receptors

Journal of Neuroinflammation, 2020
Background Cinobufagin is the major bufadienolide of Bufonis venenum (Chansu), which has been traditionally used for the treatment of chronic pain especially cancer pain. The current study aimed to evaluate its antinociceptive effects in bone cancer pain
Evhy Apryani, Usman Ali, Zi-Ying Wang, Hai-Yun Wu, Xiao-Fang Mao, Khalil Ali Ahmad, Xin-Yan Li, Yong-Xiang Wang   +7 more
doaj   +1 more source