Results 41 to 50 of about 30,353 (219)
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
ENDORPHIN MASSAGE EFEKTIF MENURUNKAN NYERI PUNGGUNG IBU HAMIL TRIMESTER III
Jurnal Ilmiah Kesehatan, 2019 Setiap ibu hamil trimester III akan mengalami perubahan fisiologis yang meliputi perubahan fisik dan psikologis. Salah satu perubahan fisik yang dialami ibu hamil trimester III adalah nyeri punggung yang menimbulkan ketidaknyamanan selama kehamilan ...
wulan diana
doaj +1 more source
Physiological Reports, 2022 Exercise‐induced hypoalgesia (EIH) is characterized as the pain reduction after an exercise session and it seems to be related to the release of plasma β‐endorphin.
Marta Silva Santos +7 more
doaj +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Effects of ?-Endorphin on Plasma Glucose Levels [PDF]
, 2010 Healthy, and insulin-deficient (streptozotocin-induced diabetic, STZ) Sprague-Dawley rats were used to investigate the effects of different closes of beta-endorphin (25 and 50 mu g/kg) on plasma beta-endorphin, insulin, glucagon, and glucose levels at 15-
Başpınar, Nuri, Akalın, Pınar Peker
core +1 more source
Frontiers in Behavioral Neuroscience, 2021 Endogenous opioids have been implicated in cocaine reward. However, the role of each opioid peptide in this regard is unknown. Notably, the role of each peptide in extinction and reinstatement is not fully characterized. Thus, we assessed whether cocaine-
Prableen K. Singh, Kabirullah Lutfy
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux +26 more
wiley +1 more source
Endogenous opioid signaling in the retina modulates sleep/wake activity in mice
Neurobiology of Sleep and Circadian Rhythms, 2022 Circadian sleep/wake rhythms are synchronized to environmental light/dark cycles in a process known as photoentrainment. We have previously shown that activation of β-endorphin-preferring μ-opioid receptors (MORs) inhibits the light-evoked firing of ...
Casey-Tyler Berezin +5 more
doaj +1 more source
Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source
Annals of MedicineBackground This study compared postoperative pain and analgesic requirements in women who underwent cesarean section (CS) in the morning and afternoon.Summary background data It is unclear whether there was difference in postoperative pain intensity and ...
Bin Shu +7 more
doaj +1 more source