Results 51 to 60 of about 20,058 (181)

Development and validation of the felt safeness in the therapeutic relationship questionnaire

open access: yesPsychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Objective To develop and evaluate the Felt Safeness in the Therapeutic Relationship Questionnaire (FSTRQ), a novel measure of someone's sense of social safeness within the therapeutic relationship. Method 226 participants completed online questionnaires including FSTRQ and measures of overall social safeness, therapeutic alliance, positive ...
Emily Hesselink, Jasmin Langdon‐Daly
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Step into action: how reminders shape engagement in fitness apps

open access: yesEconomica, Volume 93, Issue 372, Page 1225-1259, October 2026.
Abstract Regular exercise offers well‐documented health benefits, and mobile applications are increasingly used to promote physical activity. In this study, we conduct a large‐scale randomized controlled trial with 20,187 users of the WeWard app in France to evaluate the effectiveness of different message framings and intervention durations on app ...
Beatrice Braut   +2 more
wiley   +1 more source

Comorbidity Mechanism and Management of Chronic Low Back Pain and Major Depressive Disorder: From Neural Circuit Remodeling to Precision Medicine

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objective This review systematically elaborates multi‐system interactive mechanisms underlying comorbid chronic low back pain (CLBP) and major depressive disorder (MDD), synthesizes recent advances in diagnosis, treatment, and management, and proposes precision medicine directions to address clinical challenges, including missed diagnosis ...
Lin Faqu   +3 more
wiley   +1 more source

The jeong and haan of Vincent van Gogh: neuropeptides of bondedness and loss

open access: yesFrontiers in Psychology
We introduce two Korean-named yet transcultural feelings, jeong and haan, to fill gaps in neuroscientific understanding of mammalian bondedness, loss, and aggression.
Sung W. Lee   +5 more
doaj   +1 more source

The Effect of Maternal Lullaby Singing, Affectionate Touch, and a Developmental Support Program on Comfort and Development in Premature Infants: A Randomized Controlled Trial

open access: yesNursing Open, Volume 13, Issue 9, September 2026.
ABSTRACT Aim Premature infants require interventions supporting comfort in the NICU and development after discharge. Therefore, this study examined the effects of maternal affectionate touch and lullaby singing on early comfort and of a developmental support programme on subsequent development.
Funda Güler, Hüsniye Çalişir
wiley   +1 more source

Activation of GPR40 produces mechanical antiallodynia via the spinal glial interleukin-10/β-endorphin pathway

open access: yesJournal of Neuroinflammation, 2019
Background The G protein-coupled receptor 40 (GPR40), broadly expressed in various tissues such as the spinal cord, exerts multiple physiological functions including pain regulation.
Xiao-Fang Mao   +5 more
doaj   +1 more source

Effects of Perioperative Music Interventions on Emotional Outcomes in Children and Adolescents: A Systematic Review and Meta‐Analysis Integrating Developmental Psychology and Music Education Perspectives

open access: yesPediatric Anesthesia, Volume 36, Issue 9, Page 1052-1077, September 2026.
ABSTRACT Objective To evaluate the effects of perioperative music interventions on emotional outcomes (preoperative anxiety, postoperative fear, emergence delirium) and related physiological parameters in children and adolescents undergoing surgery, and to examine potential effect modifiers.
Yuchen Wen   +4 more
wiley   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan   +3 more
wiley   +1 more source

ACTH suppression and adverse effects of cabergoline in horses with pituitary pars intermedia dysfunction

open access: yesEquine Veterinary Education, Volume 38, Issue 9, Page e622-e630, September 2026.
Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken   +5 more
wiley   +1 more source

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