Results 1 to 10 of about 15,576 (174)

Research in Endorphins and Schizophrenia* [PDF]

Schizophrenia Bulletin, 1979
It has been suggested that the newly discovered endogenous opiate peptides (called endorphins) might play a role in the symptoms of schizophrenia. The administration of narcotic antagonists provides both a test of the hypothesis and a potential treatment.
Glenn C. Davis, Monte S. Buchsbaum, William E. Bunney   +2 more
openalex   +4 more sources

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis [PDF]

Small, Volume 21, Issue 26, July 3, 2025.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun, Nicholas Andrikopoulos, Guofang Zhang, Yuying Liu, Xiufang Liang, Dongjie Li, Xiaoman Suo, Yue Wang, Yuhuan Li, Chuang Wang, Yang Li, Pu Chun Ke, Feng Ding   +12 more
wiley   +2 more sources

Endorphins and exercise [PDF]

Clinical Cardiology, 1984
It is generally accepted that serious exercise training leads to marked menstrual irregularity and frequently complete amenorrhea in females, due to a decrease in the release of hypothalamic gonadotrophin releasing hormone (GmRH). The recent demonstration of a rise in plasma met-enkephalin during this process suggests an etiological role for endogenous
Victoria J. Harber, John R. Sutton
openaire   +6 more sources

Hyperthermia and endorphins

Biomedicine & Pharmacotherapy, 1993
This paper discusses the role of endogenous opioids in response to hyperthermia and the alterations observed in drug or alcohol addicts. Endorphins, rather than enkephalins are involved in adaptation to heat in the central nervous system. The pituitary secretion of beta endorphin together with ACTH in response to thermal stress provided the opportunity
P.P. Vescovi, V. Coiro
openaire   +3 more sources

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Current and novel biomarkers in cardiogenic shock

European Journal of Heart Failure, EarlyView.
A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of cardiogenic shock: progression from cardiac dysfunction/stress, through to inflammation and end‐organ dysfunction.
Victor Galusko, Florian A. Wenzl, Christophe Vandenbriele, Vasileios Panoulas, Thomas F. Lüscher, Diana A. Gorog   +5 more
wiley   +1 more source

A Study on the Addictive Feature of Nonsuicidal Self‐Injury in Adolescents With Depression Disorders and Its Correlation With Serum Beta‐Endorphin Concentration and Neural Reward Responsiveness

iRADIOLOGY, EarlyView.
NSSI is addictive in adolescents with depression disorders. It may be related to the decrease of serum beta‐endorphin concentration and the activation of brain reward system. ABSTRACT Background Nonsuicidal self‐injury (NSSI) in adolescents with depression disorders often exhibits addictive patterns, potentially linked to serum beta‐endorphin levels ...
Jie Li, Xiaogang Zhu, Peiwen Zhang, Yuxing Wang, Jian Zhong, Yiming Wang, Lixia Yang   +6 more
wiley   +1 more source

Sun Exposure Behaviors of Patients With Moderate‐to‐Severe Psoriasis: Results From the French PSOBIOTEQ Cohort

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Tanning addiction is a behavioral addiction characterized by an irrepressible desire for sun or ultraviolet light exposure. It is thought to affect 10% to 25% of the population. Objectives This study aimed to estimate the prevalence of this behavior in patients with moderate‐to‐severe psoriasis and identify associated factors ...
E. Mahé, R. Curmin, C. Paul, H. Bachelez, M. Beylot‐Barry, N. Beneton, A. Dupuy, P. Joly, D. Jullien, M.‐A. Richard, M. Viguier, E. Sbidian, O. Chosidow, F. Tubach, the PsoBioTeq Study group   +14 more
wiley   +1 more source

NEVIGRAV Study: A Case–Control Analysis on Changes in Melanocytic Nevi During Pregnancy

The Journal of Dermatology, EarlyView.
ABSTRACT Pregnancy can influence modifications and appearance of melanocytic nevi, but studies report inconsistent findings, often lacking standardized methods and comparison groups. This study evaluates dermoscopic changes in nevi and the development of new melanocytic lesions in pregnant women using full‐body photography and digital dermoscopy ...
Vincenzo Maione, Anna Venturuzzo, Stefano Bighetti, Carola Romanó, Zeno Fratton, Enzo Errichetti, Marina Venturini, Luca Bettolini   +7 more
wiley   +1 more source

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng, Jasper F. Ooms, Erik H. J. Danen, Laura H. Heitman   +3 more
wiley   +1 more source