Local analgesia of electroacupuncture is mediated by the recruitment of neutrophils and released β-endorphins. [PDF]
Pain, 2023Supplemental Digital Content is Available in the Text. Electroacupuncture recruited β-endorphins (β-END)-containing ICAM-1+/CD11b+ immune cells and increased the β-END content at the site of inflammatory.
Shi JT+9 more
europepmc +2 more sources
Common precursor to corticotropins and endorphins.
Proceedings of the National Academy of Sciences of the United States of America, 1977Double-antibody immunoprecipitation procedures with antisera to endorphins and to corticotropin (ACTH) were used to study the biosynthesis of these peptides in a mouse pituitary tumor cell line. Cultures were incubated with a (3)H-labeled amino acid, and
R. Mains, B. Eipper, N. Ling
semanticscholar +2 more sources
Physical exercise has wide-ranging benefits to cognitive functioning and mental state, effects very closely resembling enhancements to hippocampal functioning.
Timothy J. Schoenfeld, Chance Swanson
doaj +2 more sources
N-methyl-D-aspartate Receptors and Depression: Linking Psychopharmacology, Pathology and Physiology in a Unifying Hypothesis for the Epigenetic Code of Neural Plasticity [PDF]
PharmaceuticalsUncompetitive NMDAR (N-methyl-D-aspartate receptor) antagonists restore impaired neural plasticity, reverse depressive-like behavior in animal models, and relieve major depressive disorder (MDD) in humans.
Stefano Comai+7 more
doaj +2 more sources
Research in Endorphins and Schizophrenia* [PDF]
Schizophrenia Bulletin, 1979It has been suggested that the newly discovered endogenous opiate peptides (called endorphins) might play a role in the symptoms of schizophrenia. The administration of narcotic antagonists provides both a test of the hypothesis and a potential treatment.
William E. Bunney+2 more
openaire +4 more sources
Locomotor activation induced by infusion of endorphins into the ventral tegmental area: evidence for opiate-dopamine interactions. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1980beta-Endorphin in nanomole quantities produced a stimulation of locomotor activity when infused into the region of the dopamine cell bodies of the ventral tegmental area (VTA) in rats. alpha-, gamma-, and des-Tyr-gamma-endorphin produced similar effects,
L. Stinus+4 more
semanticscholar +2 more sources
A Preliminary Study on the Interplay between the Serum Levels of Neurotransmitters and Thyroid Hormones for the Evaluation of the Behavioral Phenotype of Dogs [PDF]
Animals, 2023A total of 112 dogs (49 males and 63 females) belonging to different breeds (i.e., Boxer, Cirneco dell’Etna, Fonni’s Dog, Labrador, Crossbreed, German Shepherd, Pit Bull, Shar-Pei, Yorkshire) were analyzed to compare the serum concentration of serotonin,
Raffaella Cocco+6 more
doaj +2 more sources
Lymphocyte production of endorphins and endorphin-mediated immunoregulatory activity
The Journal of Immunology, 1985The immune and neuroendocrine systems appear able to communicate with each other by virtue of signal molecules (hormones) and receptors common to both systems. This review summarizes our data concerning the production of one type of neuroendocrine hormone, endorphins (END), by stimulated lymphocytes.
E M, Smith+2 more
openaire +3 more sources
It is generally accepted that serious exercise training leads to marked menstrual irregularity and frequently complete amenorrhea in females, due to a decrease in the release of hypothalamic gonadotrophin releasing hormone (GmRH). The recent demonstration of a rise in plasma met-enkephalin during this process suggests an etiological role for endogenous
Victoria J. Harber, John R. Sutton
openaire +6 more sources
Introduction Endorphins have been associated with analgesia and pleasurable activities. However, the so-called “happy chemicals” are far more complex than initially thought. Research shows that their impact on human behavior is modulatory, with the main
M. Conde Moreno, F. Ramalheira
doaj +1 more source