Results 91 to 100 of about 104,986 (258)

A comparative analysis of prognostic regression models and machine learning algorithms in surgical decision-making of cardial submucosal tumors

Gastroenterology & Endoscopy
Background and aims: Non-tunneling and submucosal tunneling endoscopic resection (STER) techniques are the most frequent treatments for cardial submucosal tumor (SMT).
Zi-Han Geng, Yan Zhu, Pei-Yao Fu, Yi-Fan Qu, Quan-Lin Li, Ping-Hong Zhou   +5 more
doaj   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Primary intestinal lymphangiectasia diagnosed by capsule endoscopy and double balloon enteroscopu [PDF]

, 2011
Primary intestinal lymphangiectasia (PIL) is a rare disorder characterized by dilated intestinal lymphatics and the development of protein-losing enteropathy. Patients with PIL develop hypoalbuminemia, hypocalcemia, lymphopenia and hypogammaglobulinemia,
정주원, 한석주, 박정엽, 김희만, 송시영, 오탁근   +5 more
core   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Clinicopathological and Genetic Features in Superficial Nonampullary Duodenal Epithelial Tumors

Gastroenterology Research and Practice
Conclusions:GNAS mutations are more common in gastric-type SNADETs than in the intestinal type. As GNAS mutations are continuously present from adenoma to adenocarcinoma, resection at the adenoma stage is desirable.
Atsushi Sawada, Kingo Hirasawa, Makoto Sugimori, Yuichiro Ozeki, Ryosuke Ikeda, Masafumi Nishio, Takehide Fukuchi, Ryosuke Kobayashi, Hiroaki Kaneko, Chiko Sato, Yoshiaki Inayama, Chikara Kunisaki, Shin Maeda   +12 more
doaj   +1 more source

A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases

Advanced Science, EarlyView.
A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Heng Zhang, Yichong Sun, Xiaoting Zhang, Chi‐Kwan Lee, Zheng Li, Yehui Li, Huarong Chen, Paul D. Mitcheson   +7 more
wiley   +1 more source

A hairy endoscopy

Endoscopy, 2022
Katherine E. Maldonado Cardona, José G. Ruiz Rodríguez, José R. Aguirre Ayala, Abel A. Sánchez Orozco, Jefferson A. Jimenez Espinosa, Sahira F. Pereira Molina, Marco A. Villamar Barrera   +6 more
openaire   +2 more sources

Non‐Invasively Quantitative Raman Imaging for Calculation of Lymphatic Transport Kinetics of Micelles in Mice

Advanced Science, EarlyView.
Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Yunlu Li, Hongzheng Lin, Sheng Yu, Yunhui Liao, Teng Huang, Zeyu Xiao, Wei Lu   +6 more
wiley   +1 more source

Appropriateness of gastrointestinal endoscopy: risk of complications.

, 1999
The balance between risks and benefits of gastrointestinal endoscopy for a given patient is essential in defining the appropriate use of endoscopic procedures.
Burnand, B., Vader, J.P., Dubois, R.W., Gonvers, J.J., Froehlich, F., null Gonvers*, null Burnand**, null Dubois***, null Vader**, null Froehlich*   +9 more
core   +1 more source

A Tumor‐Boundary Niche Enriched for PD‐1+CD8+T Cells and BTLA+B Cells Drives Resistance to Immunotherapy in NSCLC

Advanced Science, EarlyView.
A spatial niche composed of BTLA+B cells and CD8+T cells is enriched at the tumor boundary in non‐small cell lung cancer. Within this specialized niche, BTLA+B cells act as a dominant source of IL‐6, upregulating PD‐1 on CD8+T cells via STAT3 signaling.
Jiajuan Wu, Shiying Guo, Leilei Lv, Guiqin Fan, Yu Shen, Qiuxia Qu, Cheng Chen   +6 more
wiley   +1 more source