Results 101 to 110 of about 104,986 (258)

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

open access: yesAdvanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan   +7 more
wiley   +1 more source

Eye-tracking dataset of endoscopist-AI teaming during colonoscopy: Retrospective and real-time acquisition

open access: yesScientific Data
Recent studies have demonstrated that integrating AI into colonoscopy procedures significantly improves the adenoma detection rate (ADR) and reduces the adenoma miss rate (AMR).
Yan Zhu   +7 more
doaj   +1 more source

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

open access: yesAdvanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu   +17 more
wiley   +1 more source

Upper Endoscopy, Endoscopic Ultrasound or Computer Tomography?

open access: yes, 2016
The majority of foregut subepithelial lesions (SEL) are discovered incidentally during endoscopy or cross-sectional imaging. Consensus guidelines recommend performing EUS to further characterize and sample SELs.
Murad, Faris   +7 more
core   +1 more source

A Robust Bio‐Supportive Hydrogel Patch for Full‐Thickness Repair of Gastroesophageal Defects

open access: yesAdvanced Science, EarlyView.
Gastroesophageal defect repair remains a formidable clinical challenge plagued by high leakage and life‐threatening complications. We develop a double‐disc, highly crystalline PVA‐based RBS hydrogel patch featuring suture‐free sealing, robust acid/enzyme resistance and mechanical durability.
Xingqi Song   +13 more
wiley   +1 more source

RHOJ derived peptide promotes chemosensitivity by inhibiting glutamine metabolism in gastric cancer

open access: yesJournal of Translational Medicine
Background Chemoresistance is a cause of chemotherapy failure in gastric cancer (GC) treatment. Recent studies have shown that the dysregulation of glutamine metabolism plays a pivotal role in promoting chemoresistance.
Jian Li   +8 more
doaj   +1 more source

Comparison between the effectiveness of oral phloroglucin and cimetropium bromide as premedication for diagnostic esophagogastroduodenoscopy: An open-label, randomized, comparative study

open access: yes, 2018
Background/Aims: Suppression of gastrointestinal (GI) peristalsis during GI endoscopy commonly requires antispasmodic agents such as hyoscine butylbromide, atropine, glucagon, and cimetropium bromide. This study examined the efficacy of oral phloroglucin
정성애   +3 more
core   +1 more source

Topological Quantum Biomaterials Enable Pyroptosis‐Senescence Coupling for Enhanced Colorectal Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This work reports conceptually unprecedented topological quantum biomaterials derived from engineered Pd3Sn nanostrips for oncological applications. Their near‐Fermi‐level electronic architecture and superior interfacial charge transport facilitate ultrasound‐amplified redox reactions and efficient ROS generation.
Zilu Chen   +10 more
wiley   +1 more source

Peroral Endoscopic Myotomy for Esophageal Achalasia by HybridKnife: A Case Report

open access: yesCase Reports in Gastrointestinal Medicine, 2012
This paper presented a case of esophageal achalasia treated by peroral endoscopic myotomy with HybridKnife and discuss the feasibility and the possible advantages of using it.
Ping-Hong Zhou   +6 more
doaj   +1 more source

An Expertise Transfer Framework For Autonomous Surgical Assistance

open access: yesAdvanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao   +12 more
wiley   +1 more source

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