Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy [PDF]
Cell Reports, 2023 Summary: Chaperone-mediated autophagy (CMA) and endosomal microautophagy (eMI) are pathways for selective degradation of cytosolic proteins in lysosomes and late endosomes, respectively. These autophagic processes share as a first step the recognition of
Gregory J. Krause +14 more
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Diving into the Evolutionary History of HSC70-Linked Selective Autophagy Pathways: Endosomal Microautophagy and Chaperone-Mediated Autophagy [PDF]
Cells, 2022 Autophagy is a pleiotropic and evolutionarily conserved process in eukaryotes that encompasses different types of mechanisms by which cells deliver cytoplasmic constituents to the lysosome for degradation.
Florian Beaumatin +2 more
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Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila [PDF]
Life Science Alliance, 2021 Drosophila EPS8-family protein Arouser is constitutively degraded by endosomal microautophagy; its stabilisation upon starvation is essential to the animal adaptation and survival. Hunger drives food-seeking behaviour and controls adaptation of organisms
Anne-Claire Jacomin +12 more
doaj +2 more sources
Safeguarding Lysosomal Homeostasis by DNAJC5/CSPα-Mediated Unconventional Protein Secretion and Endosomal Microautophagy [PDF]
Frontiers in Cell and Developmental Biology, 2022 Neuronal ceroid lipofuscinosis (NCL) is a collection of genetically inherited neurological disorders characterized by vision loss, seizure, brain death, and premature lethality.
Juhyung Lee, Yue Xu, Yihong Ye
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Hepatitis C virus NS5A protein promotes the lysosomal degradation of diacylglycerol O-acyltransferase 1 (DGAT1) via endosomal microautophagy [PDF]
Autophagy Reports, 2022 Many viruses often use a protein degradation system (e.g., the ubiquitin-proteasome pathway or lysosome pathway) to modulate viral propagation and viral pathogenesis.
Putu Yuliandari +9 more
doaj +2 more sources
Endosomal microautophagy is activated by specific cellular stresses in trout hepatocytes [PDF]
Scientific ReportsEndosomal microautophagy (eMI) is a recently discovered autophagic process where cytosolic proteins are selectively captured in late endosome/multivesicular bodies (LE/MVB).
Emilio J. Vélez +7 more
doaj +2 more sources
Nuclear Microautophagy Drives Vacuolar Targeting of Yeast Iron-Regulated Proteins During Lipid and Iron Limitation. [PDF]
MicrobiologyopenAft1 and Cth2 are essential for Saccharomyces cerevisiae adaptation to iron deficiency, but in mga2Δ cells, PMN drives their mislocalization to the vacuole. Although PMN inhibition reduces this mislocalization, it does not restore their functional activity. Created in BioRender. Puig, S. (2026) https://BioRender.com/gfhuez3.
Jordá T, Puig S.
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Reduced endosomal microautophagy activity in aging associates with enhanced exocyst-mediated protein secretion [PDF]
Aging Cell, 2022 Myriam Gorospe +2 more
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Selective endosomal microautophagy is starvation-inducible in Drosophila [PDF]
Autophagy, 2016 Andreas Jenny +2 more
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Endosomal microautophagy is an integrated part of the autophagic response to amino acid starvation [PDF]
Autophagy, 2019 Steingrim Svenning +2 more
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