Results 21 to 30 of about 24,168 (116)

MALAT1 affects atherosclerosis by regulating endothelial cell’s microautophagy [PDF]

open access: yes, 2023
Autophagy of vessels endothelial cells is the critical pathological process in atherosclerosis (AS). Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a kind of long non-coding RNA (lncRNA) that regulates the autophagy of vessels ...
Runqi Zhang, Zhang Runqi
core   +2 more sources

The role of motor proteins in endosomal sorting [PDF]

open access: yes, 2011
Microtubule motor proteins play key roles in the spatial organization of intracellular organelles as well as the transfer of material between them.
Hunt, Sylvie   +3 more
core   +1 more source

Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

open access: yesBMC Biology, 2020
Background In fly brains, the Drosophila Adar (adenosine deaminase acting on RNA) enzyme edits hundreds of transcripts to generate edited isoforms of encoded proteins.
Anzer Khan   +8 more
doaj   +1 more source

Microautophagy in Plants: Consideration of Its Molecular Mechanism [PDF]

open access: yes, 2020
Microautophagy is a type of autophagy. It is characterized by direct enclosing with the vacuolar/lysosomal membrane, which completes the isolation and uptake of cell components in the vacuole.
Andisheh Poormassalehgoo   +7 more
core   +1 more source

Eating Locally: Microautophagy and Protein Turnover at the Synapse [PDF]

open access: yes, 2015
Mechanisms of local protein quality control in the presynaptic nerve terminal remain largely unknown. In this issue of Neuron, Uytterhoeven et al. (2015) describe a form of synaptic endosomal microautophagy controlling protein rejuvenation, critical for ...
McPherson, Peter S.
core   +1 more source

Evidence for ESCRT- and clathrin-dependent microautophagy [PDF]

open access: yes, 2017
大隅Atg分子を必要としないミクロオートファジーの新しいメカニズム. 京都大学プレスリリース. 2017-08-25.Microautophagy refers to a mode of autophagy in which the lysosomal or vacuolar membrane invaginates and directly engulfs target components.
Yoko Kagohashi   +13 more
core   +1 more source

Early endosomes and endosomal coatomer are required for autophagy [PDF]

open access: yes, 2009
Autophagy, an intracellular degradative pathway, maintains cell homeostasis under normal and stress conditions. Nascent double-membrane autophagosomes sequester and enclose cytosolic components and organelles, and subsequently fuse with the endosomal ...
Tooze, Sharon A.   +2 more
core   +4 more sources

Endosomal-associated RFFL facilitates mitochondrial clearance by enhancing PRKN/parkin recruitment to mitochondria

open access: yes, 2022
Mutations in the ubiquitin ligase PRKN (parkin RBR E3 ubiquitin protein ligase) are associated with Parkinson disease and defective mitophagy. Conceptually, PRKN-dependent mitophagy is classified into two phases: 1.
Nikhil Dev Narendradev (12338818)   +5 more
core   +1 more source

Selective endosomal microautophagy is starvation-inducible in Drosophila

open access: yes, 2016
Autophagy delivers cytosolic components to lysosomes for degradation and is thus essential for cellular homeostasis and to cope with different stressors.
Bindi Patel (808704)   +4 more
core   +1 more source

The Role of Oxidative Stress in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon   +3 more
wiley   +1 more source

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