Results 241 to 250 of about 37,425 (325)
Extracellular vesicles: cargo loading, degradation and secretory pathways, and their intersection with autophagy. [PDF]
Ju J +4 more
europepmc +1 more source
ABSTRACT Antibody‐drug conjugates (ADCs) are innovative drugs composed of cytotoxic molecules (payload) linked to antibodies, that selectively target and kill cancer cells upon internalization. In vivo, ADCs exist as intact molecules, naked antibodies, or released, unconjugated (linker‐)payload.
Pauline L. M. Buitelaar +4 more
wiley +1 more source
The Dynamics of the ESCRT Machinery in Open Mitosis from Physiology to Pathology. [PDF]
La Torre M +3 more
europepmc +1 more source
A newly established 3D correlative cryogenic fluorescence microscopy, focused ion beam scanning electron microscopy, and soft x‐ray tomography workflow allowed for enough contrast and resolution to quantify the intracellular uptake of zirconyl‐containing inorganic–organic hybrid nanoparticles as a novel chemotherapeutic drug delivery system into ...
Pavitra Sokke Rudraiah +7 more
wiley +1 more source
The green ESCRTs: Newly defined roles for ESCRT proteins in plants. [PDF]
Weiner E +4 more
europepmc +1 more source
Dendrogenin A stimulates, via LXRβ, the expression and activity of enzymes responsible for the biosynthesis of the phospholipid BMP. BMP is a key determinant of the antitumour immunogenicity of exosomes secreted by DDA‐treated melanoma and triple‐negative breast cancer cells and enhances mouse survival and anti‐PD‐1 therapy in melanoma.
Julio Buñay +11 more
wiley +1 more source
The interplay between the extracellular matrix and extracellular vesicle-associated microRNAs. [PDF]
Wu Y, Toldo N, Fabbri M.
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for liquid biopsy.
Biancamaria Pierri +5 more
wiley +1 more source
The Biology of Endosomal Escape: Strategies for Enhanced Delivery of Therapeutics. [PDF]
Chahal GS +3 more
europepmc +1 more source

