Results 1 to 10 of about 73,794 (208)
Matrix compliance and the regulation of cytokinesis
Biology Open, 2015 Integrin-mediated cell adhesion to the ECM regulates many physiological processes in part by controlling cell proliferation. It is well established that many normal cells require integrin-mediated adhesion to enter S phase of the cell cycle.
Savitha Sambandamoorthy +6 more
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eLife, 2022 The 12 related human ESCRT-III proteins form filaments that constrict membranes and mediate fission, including during cytokinetic abscission. The C-terminal tails of polymerized ESCRT-III subunits also bind proteins that contain Microtubule-Interacting ...
Dawn M Wenzel +6 more
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Septin Remodeling During Mammalian Cytokinesis
Frontiers in Cell and Developmental Biology, 2021 Cytokinesis mediates the final separation of a mother cell into two daughter cells. Septins are recruited to the cleavage furrow at an early stage. During cytokinetic progression the septin cytoskeleton is constantly rearranged, ultimately leading to a ...
Giulia Russo, Michael Krauss
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Frontiers in Genetics, 2020 The human Periodontal Ligament Stem Cells (hPDLSCs) exhibit self-renewal capacity and clonogenicity potential. The Extracellular Vesicles (EVs) secreted by hPDLSCs are particles containing lipids, proteins, mRNAs, and non-coding RNAs, among which ...
Luigi Chiricosta +7 more
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Regulation of the Total Cell Surface Area in Dividing Dictyostelium Cells
Frontiers in Cell and Developmental Biology, 2020 When a cell divides into two daughter cells, the total cell surface area should increase. There are two models for membrane supply to support cell division: (1) unfolding of small surface membrane reservoirs such as microvilli or wrinkles and (2 ...
Masahito Tanaka +2 more
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The MERS-CoV N Protein Regulates Host Cytokinesis and Protein Translation via Interaction With EF1A
Frontiers in Microbiology, 2021 Middle East respiratory syndrome coronavirus (MERS-CoV), a pathogen causing severe respiratory disease in humans that emerged in June 2012, is a novel beta coronavirus similar to severe acute respiratory syndrome coronavirus (SARS-CoV).
Lin Zhu +14 more
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The Role of the Cell Integrity Pathway in Septum Assembly in Yeast
Journal of Fungi, 2021 Cytokinesis divides a mother cell into two daughter cells at the end of each cell cycle and proceeds via the assembly and constriction of a contractile actomyosin ring (CAR).
Cesar Roncero +4 more
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Anillin Phosphorylation Controls Timely Membrane Association and Successful Cytokinesis.
PLoS Genetics, 2017 During cytokinesis, a contractile ring generates the constricting force to divide a cell into two daughters. This ring is composed of filamentous actin and the motor protein myosin, along with additional structural and regulatory proteins, including ...
Hyunjung Kim +4 more
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Yorkie and JNK Control Tumorigenesis in Drosophila Cells with Cytokinesis Failure
Cell Reports, 2018 Summary: Cytokinesis failure may result in the formation of polyploid cells, and subsequent mitosis can lead to aneuploidy and tumor formation. Tumor suppressor mechanisms limiting the oncogenic potential of these cells have been described.
Stephan U. Gerlach +2 more
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A novel mode of cytokinesis without cell-substratum adhesion
Scientific Reports, 2017 Cytokinesis is a final step in cell division. Dictyostelium cells, a model organism for the study of cytokinesis, have multiple modes, denoted cytokinesis A, B, C, and D.
Risa Taira, Shigehiko Yumura
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