Central Role of the Actomyosin Ring in Coordinating Cytokinesis Steps in Budding Yeast [PDF]
Journal of FungiEukaryotic cells must accurately transfer their genetic material and cellular components to their daughter cells. Initially, cells duplicate their chromosomes and subsequently segregate them toward the poles.
Magdalena Foltman, Alberto Sanchez-Diaz
doaj +4 more sources
Spatiotemporal recruitment of RhoGTPase protein GRAF inhibits actomyosin ring constriction in Drosophila cellularization [PDF]
eLife, 2021 Actomyosin contractility is regulated by Rho-GTP in cell migration, cytokinesis and morphogenesis in embryo development. Whereas Rho activation by Rho-GTP exchange factor (GEF), RhoGEF2, is well known in actomyosin contractility during cytokinesis at the
Swati Sharma, Richa Rikhy
doaj +2 more sources
The LDL pathway regulates actomyosin ring dynamics necessary for optimal cell wound repair [PDF]
microPublication BiologyIndividual cells must rapidly repair any cortical damage from environmental or physiological stresses, to survive and to contribute to maintaining the proper function of tissues and organs.
Geethika Burugupally +3 more
doaj +2 more sources
Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels [PDF]
eLife, 2020 Cytokinesis, which enables the physical separation of daughter cells once mitosis has been completed, is executed in fungal and animal cells by a contractile actin- and myosin-based ring (CAR).
Elisa Gómez-Gil +9 more
doaj +2 more sources
Cell Reports, 2020 Summary: Entosis is a cell-in-cell (CIC)-mediated death program. Contractile actomyosin (CA) and the adherens junction (AJ) are two core elements essential for entotic CIC formation, but the molecular structures interfacing them remain poorly understood.
Manna Wang +12 more
doaj +3 more sources
Mechanoregulated inhibition of formin facilitates contractile actomyosin ring assembly [PDF]
Nature Communications, 2017 The fission yeast cytokinetic ring assembles by Search-Capture-Pull-Release from precursor nodes that include formin Cdc12 and myosin Myo2. The authors reconstitute Search-Capture-Pull in vitro and find that Myo2 pulling on Cdc12-associated actin ...
Dennis Zimmermann +7 more
doaj +2 more sources
Hof1 and Rvs167 have redundant roles in actomyosin ring function during cytokinesis in budding yeast. [PDF]
PLoS ONE, 2013 The Hof1 protein (Homologue of Fifteen) regulates formation of the primary septum during cytokinesis in the budding yeast Saccharomyces cerevisiae, whereas the orthologous Cdc15 protein in fission yeast regulates the actomyosin ring by using its F-BAR ...
Pedro Junior Nkosi +3 more
doaj +2 more sources
CHI3L1 promotes cell division through activation of RhoA in lung cancer cells [PDF]
Cell Communication and SignalingBackground Cytokinesis, the final stage of cell division, is crucial for maintaining genomic stability. Dysregulation of cytokinesis can contribute to cancer development. This study aimed to investigate the role of CHI3L1 in cytokinesis and its influence
Ji Eun Yu +9 more
doaj +2 more sources
Distinct actomyosin–septin coordination governs conidiation and septation in Verticillium dahliae [PDF]
mLifeConidiation is the primary mode of reproduction in filamentous fungi and is essential for the dispersal of pathogenic species. However, the fundamental cellular mechanisms regulating conidiation in plant pathogenic fungi remain largely unexplored.
Juan Tian +7 more
doaj +2 more sources
Structure of the Fission Yeast Actomyosin Ring During Constriction [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2018 Mithilesh Mishra +2 more
exaly +2 more sources